Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR089W
Length:
936
Number of sequences:
5887
Description:
YGR089W NNF2 SGDID:S000003321, Chr VII from 656960-659770, Genome Release 64-1-1, Verified ORF, "Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P41114    242   TPM1_PODCA Tropomyosin-1 OS=Podocoryne carnea...2010.035     40.8     22     47
32Q01173    284   TPM1_XENLA Tropomyosin alpha-1 chain OS=Xenop...1940.038     40.8     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
33Q5VT25    1732   MRCKA_HUMAN Serine/threonine-protein kinase M...1530.041     41.6     24     52GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
34Q3UU96    1719   MRCKA_MOUSE Serine/threonine-protein kinase M...1530.043     41.6     24     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0000226; P:microtubule cytoskeleton organization; IMP:MGI.::GO:0007097; P:nuclear migration; IMP:MGI.
35P21107    284   TPM3_MOUSE Tropomyosin alpha-3 chain OS=Mus m...1790.052     40.4     25     49GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0002102; C:podosome; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
36P06753    284   TPM3_HUMAN Tropomyosin alpha-3 chain OS=Homo ...1790.052     40.4     25     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005862; C:muscle thin filament tropomyosin; TAS:UniProtKB.::GO:0001725; C:stress fiber; IDA:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0006937; P:regulation of muscle contraction; NAS:UniProtKB.
37Q5KR47    284   TPM3_BOVIN Tropomyosin alpha-3 chain OS=Bos t...1790.052     40.4     25     49
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
38P19352    284   TPM2_CHICK Tropomyosin beta chain OS=Gallus g...2080.064     40     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
39P13105    284   TPM1_RANTE Tropomyosin alpha-1 chain OS=Rana ...2030.095     39.7     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
40P42638    284   TPM2_SCHMA Tropomyosin-2 OS=Schistosoma manso...2060.21     38.5     20     45
41A1XQV4    284   TPM3_PIG Tropomyosin alpha-3 chain OS=Sus scr...1880.35     37.7     25     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
42O95613    3336   PCNT_HUMAN Pericentrin OS=Homo sapiens (Human...1690.43     38.1     24     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0042384; P:cilium assembly; IDA:MGI.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.
43Q8CHD8    1047   RFIP3_MOUSE Rab11 family-interacting protein ...1840.5     38.1     26     51GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
GO:0030306; F:ADP-ribosylation factor binding; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0032456; P:endocytic recycling; ISS:UniProtKB.
44Q1HPU0    284   TPM1_BOMMO Tropomyosin-1 OS=Bombyx mori (Silk...2230.52     37.4     20     46
45O75154    756   RFIP3_HUMAN Rab11 family-interacting protein ...1670.53     37.7     26     52GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
GO:0030306; F:ADP-ribosylation factor binding; IPI:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:UniProtKB.::GO:0032456; P:endocytic recycling; IDA:UniProtKB.
46P48725    2898   PCNT_MOUSE Pericentrin OS=Mus musculus (Mouse...2150.64     37.7     24     47GO:0005814; C:centriole; IDA:MGI.::GO:0045171; C:intercellular bridge; IDA:MGI.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:MGI.::GO:0048854; P:brain morphogenesis; IMP:MGI.::GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035108; P:limb morphogenesis; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0061351; P:neural precursor cell proliferation; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0021772; P:olfactory bulb development; IMP:MGI.::GO:0007051; P:spindle organization; IDA:MGI.
47P19137    3084   LAMA1_MOUSE Laminin subunit alpha-1 OS=Mus mu...2160.75     37.4     20     42GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005606; C:laminin-1 complex; IDA:MGI.
GO:0005201; F:extracellular matrix structural constituent; IDA:MGI.::GO:0043208; F:glycosphingolipid binding; IDA:MGI.::GO:0005102; F:receptor binding; IEA:InterPro.
GO:0060445; P:branching involved in salivary gland morphogenesis; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; IDA:MGI.::GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IMP:MGI.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:MGI.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.::GO:0061304; P:retinal blood vessel morphogenesis; IMP:MGI.
48Q6ZQQ6    2873   WDR87_HUMAN WD repeat-containing protein 87 O...1620.85     37.4     26     52
49P15846    284   TPMM_TRICO Tropomyosin, muscle OS=Trichostron...1620.98     36.2     25     46
50Q22866    284   TPM1_CAEEL Tropomyosin isoforms a/b/d/f OS=Ca...1631     36.2     26     47GO:0005865; C:striated muscle thin filament; IDA:WormBase.
GO:0051015; F:actin filament binding; IDA:UniProtKB.
GO:0007015; P:actin filament organization; IMP:UniProtKB.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:UniProtKB.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0030835; P:negative regulation of actin filament depolymerization; IDA:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0030833; P:regulation of actin filament polymerization; IDA:WormBase.::GO:0043393; P:regulation of protein binding; IDA:WormBase.::GO:0034609; P:spicule insertion; IMP:UniProtKB.
51Q5BH90    202   ATG16_EMENI Autophagy protein 16 OS=194 / M13...1001.1     35.8     25     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
52Q604U6    1169   SMC_METCA Chromosome partition protein Smc OS...1871.1     37     26     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0030261; P:chromosome condensation; IEA:InterPro.::GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
53Q8IT89    284   TPM_HAELO Tropomyosin OS=Haemaphysalis longic...1261.6     35.8     28     55
54A6NL28    223   TPM3L_HUMAN Putative tropomyosin alpha-3 chai...2092     35     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
55Q9NFZ4    284   TPM_LEPDS Tropomyosin OS=Lepidoglyphus destru...2022     35.4     24     42
56Q13137    446   CACO2_HUMAN Calcium-binding and coiled-coil d...2632.1     35.8     25     45GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.
GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.
GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.::GO:0016032; P:viral reproduction; TAS:ProtInc.
57Q7L7X3    1001   TAOK1_HUMAN Serine/threonine-protein kinase T...1752.6     35.4     24     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:HGNC.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IDA:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
58O88664    1001   TAOK1_RAT Serine/threonine-protein kinase TAO...1752.8     35.4     24     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030295; F:protein kinase activator activity; IMP:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.
59Q5F2E8    1001   TAOK1_MOUSE Serine/threonine-protein kinase T...1752.9     35.4     24     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.
60Q60675    3106   LAMA2_MOUSE Laminin subunit alpha-2 OS=Mus mu...1823.1     35.4     23     43GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
61Q11W14    522   RNY_CYTH3 Ribonuclease Y OS=Cytophaga hutchin...773.4     35     31     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008663; F:2',3'-cyclic-nucleotide 2'-phosphodiesterase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
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