Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR083C
Length:
651
Number of sequences:
5887
Description:
YGR083C GCD2 SGDID:S000003315, Chr VII from 646815-644860, Genome Release 64-1-1, reverse complement, Verified ORF, "Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P12754    651   EI2BD_YEAST Translation initiation factor eIF...6510     1324     100     100GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:SGD.::GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD.
GO:0030234; F:enzyme regulator activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IMP:SGD.
GO:0045947; P:negative regulation of translational initiation; IBA:RefGenome.
2Q09924    467   EI2BD_SCHPO Probable translation initiation f...3793e-86     284     39     59GO:0005829; C:cytosol; IDA:PomBase.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:PomBase.
GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0045947; P:negative regulation of translational initiation; ISS:RefGenome.
3Q61749    524   EI2BD_MOUSE Translation initiation factor eIF...3771e-73     252     38     54GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
4Q54FM3    619   EI2BD_DICDI Translation initiation factor eIF...3792e-73     254     37     56GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:dictyBase.
GO:0045947; P:negative regulation of translational initiation; IBA:RefGenome.
5P41111    523   EI2BD_RABIT Translation initiation factor eIF...3773e-71     245     38     53GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
6Q63186    524   EI2BD_RAT Translation initiation factor eIF-2...3774e-70     243     37     53GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:RGD.::GO:0003743; F:translation initiation factor activity; NAS:UniProtKB.::GO:0031369; F:translation initiation factor binding; IDA:RGD.
GO:0042552; P:myelination; ISS:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
7Q9UI10    523   EI2BD_HUMAN Translation initiation factor eIF...3771e-68     239     37     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.::GO:0031369; F:translation initiation factor binding; ISS:UniProtKB.
GO:0042552; P:myelination; IMP:UniProtKB.::GO:0032057; P:negative regulation of translational initiation in response to stress; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.
8Q3T058    524   EI2BD_BOVIN Translation initiation factor eIF...3772e-66     233     37     51GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0045947; P:negative regulation of translational initiation; ISS:RefGenome.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
9Q8U4G6    324   EI2B2_PYRFU Putative translation initiation f...3396e-20     95.1     27     43
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
10Q9V281    324   EI2B2_PYRAB Putative translation initiation f...430.008     42.4     44     65
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
11O57947    324   EI2B2_PYRHO Putative translation initiation f...430.007     42.7     44     65
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
12Q54EY2    388   EI2BB_DICDI Translation initiation factor eIF...1650.00000000000001     79.7     33     53GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:dictyBase.
GO:0005525; F:GTP binding; IC:dictyBase.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0006446; P:regulation of translational initiation; ISS:dictyBase.
13Q57586    308   EI2B2_METJA Putative translation initiation f...3220.00000000000005     77     24     44
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
14D4GV73    323   EI2B2_HALVD Putative translation initiation f...480.001     45.4     35     60
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
15Q5RAR0    305   EI2BA_PONAB Translation initiation factor eIF...1560.0000000000004     73.9     33     53
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
16Q14232    305   EI2BA_HUMAN Translation initiation factor eIF...1560.0000000000004     73.9     33     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.
17Q0IIF2    305   EI2BA_BOVIN Translation initiation factor eIF...1560.000000000001     72.4     32     53GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:RefGenome.
GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
18O28242    313   EI2B2_ARCFU Putative translation initiation f...430.061     39.7     37     60
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
19Q4R4V8    305   EI2BA_MACFA Translation initiation factor eIF...1560.000000000002     72     32     52GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
20Q99LC8    305   EI2BA_MOUSE Translation initiation factor eIF...2290.000000000002     71.6     27     48GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.
21Q54I81    321   EI2BA_DICDI Translation initiation factor eIF...1910.000000000004     71.2     32     50GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
22Q64270    305   EI2BA_RAT Translation initiation factor eIF-2...2190.00000000001     69.7     28     49GO:0005850; C:eukaryotic translation initiation factor 2 complex; IDA:RGD.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IMP:RGD.::GO:0003743; F:translation initiation factor activity; IDA:RGD.
GO:0032057; P:negative regulation of translational initiation in response to stress; IMP:RGD.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
23Q90511    355   EI2BB_TAKRU Translation initiation factor eIF...1720.00000000003     69.3     27     51GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
24Q5E9B4    351   EI2BB_BOVIN Translation initiation factor eIF...2310.0000000004     65.5     24     44GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0003743; F:translation initiation factor activity; ISS:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; ISS:RefGenome.
25Q8U3J1    276   EI2BL_PYRFU Putative translation initiation f...1980.000000001     62.8     27     48
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
26P49770    351   EI2BB_HUMAN Translation initiation factor eIF...2310.000000001     63.9     24     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005851; C:eukaryotic translation initiation factor 2B complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; IDA:UniProtKB.::GO:0042552; P:myelination; IMP:UniProtKB.::GO:0014003; P:oligodendrocyte development; IMP:UniProtKB.::GO:0001541; P:ovarian follicle development; IMP:UniProtKB.::GO:0006446; P:regulation of translational initiation; TAS:UniProtKB.::GO:0009749; P:response to glucose stimulus; ISS:UniProtKB.::GO:0009408; P:response to heat; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; ISS:UniProtKB.
27Q62818    351   EI2BB_RAT Translation initiation factor eIF-2...1700.000000002     63.5     27     48GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0009408; P:response to heat; IDA:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
28Q28690    351   EI2BB_RABIT Translation initiation factor eIF...2310.000000004     62.8     23     44GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.
29Q99LD9    351   EI2BB_MOUSE Translation initiation factor eIF...1700.000000005     62.4     26     48GO:0005851; C:eukaryotic translation initiation factor 2B complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0003743; F:translation initiation factor activity; IBA:RefGenome.
GO:0051716; P:cellular response to stimulus; ISS:UniProtKB.::GO:0042552; P:myelination; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; ISS:UniProtKB.::GO:0001541; P:ovarian follicle development; ISS:UniProtKB.::GO:0006446; P:regulation of translational initiation; IBA:RefGenome.
30Q9UYB6    276   EI2BL_PYRAB Putative translation initiation f...1330.00000001     60.1     29     53
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
31Q57896    329   MTNA_METJA Putative methylthioribose-1-phosph...2170.00000001     60.5     28     47
GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
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