Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR080W
Length:
332
Number of sequences:
5887
Description:
YGR080W TWF1 SGDID:S000003312, Chr VII from 642010-643008, Genome Release 64-1-1, Verified ORF, "Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q570Y6    140   ADF8_ARATH Actin-depolymerizing factor 8 OS=A...1043.8     32     29     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
32Q9ZSK3    139   ADF4_ARATH Actin-depolymerizing factor 4 OS=A...300.15     35.8     50     67GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0009870; P:defense response signaling pathway, resistance gene-dependent; IMP:TAIR.::GO:0042742; P:defense response to bacterium; IMP:TAIR.
33Q39250    139   ADF1_ARATH Actin-depolymerizing factor 1 OS=A...300.25     35.4     50     67GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; TAS:TAIR.
GO:0030042; P:actin filament depolymerization; IDA:TAIR.
34Q9ZSK4    139   ADF3_ARATH Actin-depolymerizing factor 3 OS=A...410.022     38.1     41     68GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
35Q03048    143   COFI_YEAST Cofilin OS=Saccharomyces cerevisia...390.023     38.5     46     72GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0030042; P:actin filament depolymerization; IDA:SGD.::GO:0051014; P:actin filament severing; IDA:SGD.
36Q9FVI2    139   ADF1_PETHY Actin-depolymerizing factor 1 OS=P...250.31     35     52     76GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
37Q0DLA3    139   ADF7_ORYSJ Actin-depolymerizing factor 7 OS=O...310.024     38.1     48     77GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
38Q759P0    143   COFI_ASHGO Cofilin OS=Y-1056) (Yeast) (Eremot...1120.027     38.1     26     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
39P78929    137   COFI_SCHPO Cofilin OS=Schizosaccharomyces pom...340.036     37.7     47     82GO:0030479; C:actin cortical patch; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0071519; P:actin filament bundle assembly involved in actomyosin contractile ring formation; NAS:PomBase.::GO:0030042; P:actin filament depolymerization; TAS:PomBase.
40Q8H2P8    139   ADF9_ORYSJ Actin-depolymerizing factor 9 OS=O...1110.049     37.4     27     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
41Q6CQ22    143   COFI_KLULA Cofilin OS=1267 / NRRL Y-1140 / WM...310.054     37.4     48     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
42P30174    126   ADF_BRANA Actin-depolymerizing factor OS=Bras...310.057     37     45     74GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
43Q9FVI1    143   ADF2_PETHY Actin-depolymerizing factor 2 OS=P...290.083     36.6     45     79GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
44Q67ZM4    137   ADF7_ARATH Actin-depolymerizing factor 7 OS=A...818.6     30.8     28     46GO:0005884; C:actin filament; IDA:TAIR.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
45Q39251    137   ADF2_ARATH Actin-depolymerizing factor 2 OS=A...250.91     33.5     56     76GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
46Q8LFH6    137   ADF12_ARATH Actin-depolymerizing factor 12 OS...310.1     36.2     45     74GO:0005884; C:actin filament; IDA:TAIR.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
47Q43694    139   ADF2_MAIZE Actin-depolymerizing factor 2 OS=Z...310.11     36.2     48     71GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
48Q8SAG3    143   ADF_VITVI Actin-depolymerizing factor OS=Viti...310.11     36.2     42     74GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
49P46251    139   ADF1_MAIZE Actin-depolymerizing factor 1 OS=Z...310.12     36.2     48     71GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
50P86293    143   CADF2_PLAFX Cofilin/actin-depolymerizing fact...580.16     35.8     31     57GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
51Q8ID92    143   CADF2_PLAF7 Cofilin/actin-depolymerizing fact...580.16     35.8     31     57GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0008154; P:actin polymerization or depolymerization; ISS:GeneDB_Pfalciparum.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
52Q6BWX4    143   COFI_DEBHA Cofilin OS=0083 / IGC 2968) (Yeast...310.24     35.4     42     74GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
53Q556H5    138   COF3_DICDI Cofilin-3 OS=Dictyostelium discoid...570.96     33.5     35     54GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
54P37167    138   ACTP_ACACA Actophorin OS=Acanthamoeba castell...320.31     35     34     78GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
55O49606    141   ADF9_ARATH Actin-depolymerizing factor 9 OS=A...310.35     35     39     74GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0030041; P:actin filament polymerization; IDA:TAIR.
56Q07750    212   ADF1_CAEEL Actin-depolymerizing factor 1, iso...381.1     34.3     29     61GO:0005865; C:striated muscle thin filament; IDA:WormBase.
GO:0051015; F:actin filament binding; IDA:WormBase.
GO:0030042; P:actin filament depolymerization; IDA:WormBase.::GO:0051014; P:actin filament severing; IDA:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:WormBase.::GO:0030240; P:skeletal muscle thin filament assembly; IMP:WormBase.
57O60234    142   GMFG_HUMAN Glia maturation factor gamma OS=Ho...1090.47     34.7     27     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.::GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
GO:0006468; P:protein phosphorylation; TAS:ProtInc.
58Q9CQI3    142   GMFB_MOUSE Glia maturation factor beta OS=Mus...1090.48     34.7     28     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
59Q9ZNT3    143   ADF5_ARATH Actin-depolymerizing factor 5 OS=A...290.49     34.7     41     79GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
60Q96VU9    143   COFI_PICAD Cofilin OS=(Hansenula polymorpha)....400.53     34.3     40     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
61P0DJ27    137   COFB_DICDI Cofilin-1B OS=Dictyostelium discoi...850.55     34.3     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
records
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