rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53250 | 332 | TWF1_YEAST Twinfilin-1 OS=Saccharomyces cerev... | 332 | 0 | 676 | 100 | 100 | GO:0030479; C:actin cortical patch; TAS:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:SGD. | | | | | | | | | | GO:0008154; P:actin polymerization or depolymerization; TAS:SGD.::GO:0007121; P:bipolar cellular bud site selection; TAS:SGD.::GO:0042989; P:sequestering of actin monomers; IDA:SGD. | 2 | Q7ZXP0 | 349 | TWF2A_XENLA Twinfilin-2-A OS=Xenopus laevis (... | 301 | 9e-19 | 89 | 30 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 3 | Q9Z0P5 | 349 | TWF2_MOUSE Twinfilin-2 OS=Mus musculus (Mouse... | 296 | 1e-18 | 88.2 | 28 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0032420; C:stereocilium; IDA:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0030837; P:negative regulation of actin filament polymerization; IDA:BHF-UCL.::GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL. | 4 | Q640W2 | 349 | TWF2B_XENLA Twinfilin-2-B OS=Xenopus laevis (... | 300 | 3e-18 | 87.4 | 30 | 46 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q5ZM35 | 349 | TWF2_CHICK Twinfilin-2 OS=Gallus gallus (Chic... | 297 | 1e-17 | 85.5 | 28 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q6IBS0 | 349 | TWF2_HUMAN Twinfilin-2 OS=Homo sapiens (Human... | 296 | 1e-17 | 85.5 | 28 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030426; C:growth cone; IDA:BHF-UCL.::GO:0030027; C:lamellipodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.::GO:0032420; C:stereocilium; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL.::GO:0005080; F:protein kinase C binding; IPI:BHF-UCL. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; ISS:BHF-UCL.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0045773; P:positive regulation of axon extension; IMP:BHF-UCL.::GO:0010592; P:positive regulation of lamellipodium assembly; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0032532; P:regulation of microvillus length; IC:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 7 | Q5RFH1 | 341 | TWF2_PONAB Twinfilin-2 OS=Pongo abelii (Sumat... | 296 | 3e-17 | 84.7 | 28 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030030; P:cell projection organization; IEA:UniProtKB-KW. | 8 | Q7QG28 | 343 | TWF_ANOGA Twinfilin OS=Anopheles gambiae (Afr... | 352 | 2e-16 | 82 | 26 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | Q5I082 | 350 | TWF1_XENTR Twinfilin-1 OS=Xenopus tropicalis ... | 353 | 0.000000000000001 | 79.7 | 26 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | Q9VFM9 | 343 | TWF_DROME Twinfilin OS=Drosophila melanogaste... | 356 | 0.00000000000005 | 75.5 | 28 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IMP:UniProtKB. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IDA:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0008407; P:chaeta morphogenesis; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:UniProtKB.::GO:0010591; P:regulation of lamellipodium assembly; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase. | 11 | Q68F50 | 350 | TWF1_XENLA Twinfilin-1 OS=Xenopus laevis (Afr... | 293 | 0.0000000000001 | 74.7 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | Q91YR1 | 350 | TWF1_MOUSE Twinfilin-1 OS=Mus musculus (Mouse... | 325 | 0.0000000000001 | 74.3 | 26 | 45 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005911; C:cell-cell junction; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:BHF-UCL.::GO:0030016; C:myofibril; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:BHF-UCL.::GO:0004713; F:protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0051016; P:barbed-end actin filament capping; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; IDA:BHF-UCL. | 13 | Q6GMH3 | 347 | TWF2_DANRE Twinfilin-2 OS=Danio rerio (Zebraf... | 284 | 0.0000000000002 | 73.9 | 27 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 14 | Q5R7N2 | 350 | TWF1_PONAB Twinfilin-1 OS=Pongo abelii (Sumat... | 295 | 0.0000000000003 | 73.2 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q17A58 | 343 | TWF_AEDAE Twinfilin OS=Aedes aegypti (Yellowf... | 355 | 0.0000000000003 | 73.2 | 26 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q12792 | 350 | TWF1_HUMAN Twinfilin-1 OS=Homo sapiens (Human... | 295 | 0.0000000000005 | 72.8 | 27 | 46 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:BHF-UCL.::GO:0030175; C:filopodium; ISS:BHF-UCL.::GO:0030016; C:myofibril; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISS:BHF-UCL. | | | | | | | | | | GO:0043538; P:regulation of actin phosphorylation; IDA:BHF-UCL.::GO:0042989; P:sequestering of actin monomers; ISS:BHF-UCL. | 17 | Q5RJR2 | 350 | TWF1_RAT Twinfilin-1 OS=Rattus norvegicus (Ra... | 361 | 0.000000000001 | 71.6 | 25 | 44 | | | | | | | | | | | | | | | | | | | | | | 18 | Q298X4 | 345 | TWF_DROPS Twinfilin OS=Drosophila pseudoobscu... | 351 | 0.000000000002 | 70.5 | 26 | 43 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB. | | | | | | | | | | GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 19 | Q56JV6 | 350 | TWF1_BOVIN Twinfilin-1 OS=Bos taurus (Bovine)... | 295 | 0.00000000002 | 67.8 | 26 | 45 | | | | | | | | | | | | | | | | | | | | | | 20 | Q869T1 | 335 | TWF_DICDI Twinfilin OS=Dictyostelium discoide... | 292 | 0.00000000002 | 67.4 | 27 | 43 | GO:0015629; C:actin cytoskeleton; ISS:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; ISS:dictyBase. | | | | | | | | | | | 21 | O94399 | 328 | TWF1_SCHPO Twinfilin OS=Schizosaccharomyces p... | 229 | 0.000000005 | 60.5 | 25 | 47 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:PomBase. | | | | | | | | | | GO:0042989; P:sequestering of actin monomers; ISS:PomBase. | 22 | Q9HF97 | 143 | COFI_ZYGRO Cofilin OS=Zygosaccharomyces rouxi... | 112 | 0.0003 | 43.5 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 23 | Q07749 | 152 | ADF2_CAEEL Actin-depolymerizing factor 2, iso... | 38 | 0.0006 | 43.1 | 50 | 63 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 24 | P86292 | 122 | CADF1_PLAFX Cofilin/actin-depolymerizing fact... | 88 | 0.001 | 41.6 | 30 | 50 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; IMP:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; IMP:UniProtKB. | 25 | Q8I467 | 122 | CADF1_PLAF7 Cofilin/actin-depolymerizing fact... | 88 | 0.001 | 41.6 | 30 | 50 | GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB. | 26 | P30175 | 139 | ADF_LILLO Actin-depolymerizing factor OS=Lili... | 31 | 0.001 | 42 | 58 | 77 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | Q6C0Y0 | 153 | COFI_YARLI Cofilin OS=lipolytica). GN=COF1 Or... | 119 | 0.002 | 42 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 28 | Q9LQ81 | 140 | ADF10_ARATH Actin-depolymerizing factor 10 OS... | 43 | 0.002 | 41.6 | 47 | 65 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | Q6EUH7 | 139 | ADF1_ORYSJ Actin-depolymerizing factor 1 OS=O... | 86 | 2.8 | 32.3 | 33 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q7XSN9 | 139 | ADF6_ORYSJ Actin-depolymerizing factor 6 OS=O... | 31 | 0.003 | 40.8 | 55 | 77 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 31 | Q570Y6 | 140 | ADF8_ARATH Actin-depolymerizing factor 8 OS=A... | 104 | 3.8 | 32 | 29 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | |