UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR074W

Length:

146

Number of sequences:

5887

Description:

YGR074W SMD1 SGDID:S000003306, Chr VII from 635712-636152, Genome Release 64-1-1, Verified ORF, "Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q02260	146	SMD1_YEAST Small nuclear ribonucleoprotein Sm...	146	5e-100	290	100	100	GO:0000243; C:commitment complex; IPI:SGD.::GO:0005685; C:U1 snRNP; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
									GO:0003729; F:mRNA binding; IPI:SGD.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IMP:UniProtKB.
2	O42661	117	SMD1_SCHPO Small nuclear ribonucleoprotein Sm...	109	2e-17	78.2	45	56	GO:0000243; C:commitment complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005685; C:U1 snRNP; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
									GO:0003729; F:mRNA binding; ISS:PomBase.
									GO:0000395; P:nuclear mRNA 5'-splice site recognition; IC:PomBase.
3	P62315	119	SMD1_MOUSE Small nuclear ribonucleoprotein Sm...	109	2e-16	75.5	45	53	GO:0005737; C:cytoplasm; IDA:MGI.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
4	Q4R5F6	119	SMD1_MACFA Small nuclear ribonucleoprotein Sm...	109	2e-16	75.5	45	53	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
5	P62314	119	SMD1_HUMAN Small nuclear ribonucleoprotein Sm...	109	2e-16	75.5	45	53	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0030532; C:small nuclear ribonucleoprotein complex; TAS:ProtInc.::GO:0005689; C:U12-type spliceosomal complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.
									GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0000245; P:spliceosomal complex assembly; TAS:ProtInc.::GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.
6	Q3ZC10	119	SMD1_BOVIN Small nuclear ribonucleoprotein Sm...	109	2e-16	75.5	45	53
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
7	Q9VU02	124	SMD1_DROME Probable small nuclear ribonucleop...	109	0.00000000000002	70.1	40	52	GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.::GO:0030532; C:small nuclear ribonucleoprotein complex; ISS:UniProtKB.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.
8	Q10013	126	SMD1_CAEEL Probable small nuclear ribonucleop...	111	0.0000000000001	67.8	41	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043186; C:P granule; IDA:WormBase.
									GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
9	O35900	95	LSM2_MOUSE U6 snRNA-associated Sm-like protei...	49	0.00002	43.9	41	59	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0019901; F:protein kinase binding; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
10	Q9Y333	95	LSM2_HUMAN U6 snRNA-associated Sm-like protei...	49	0.00002	43.9	41	59	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0017070; F:U6 snRNA binding; NAS:UniProtKB.
									GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; NAS:UniProtKB.
11	Q54KX4	177	LSM4_DICDI Probable U6 snRNA-associated Sm-li...	138	0.0009	40.8	28	43	GO:0005730; C:nucleolus; ISS:dictyBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:dictyBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:dictyBase.::GO:0005688; C:U6 snRNP; ISS:dictyBase.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006402; P:mRNA catabolic process; ISS:dictyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:dictyBase.
12	Q54F84	137	Y1015_DICDI Putative uncharacterized protein ...	105	0.003	38.9	29	49
13	Q54TF6	117	LSM2_DICDI Probable U6 snRNA-associated Sm-li...	45	0.004	38.1	40	62	GO:0005730; C:nucleolus; ISS:dictyBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:dictyBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:dictyBase.::GO:0005688; C:U6 snRNP; ISS:dictyBase.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006402; P:mRNA catabolic process; ISS:dictyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:dictyBase.
14	P38203	95	LSM2_YEAST U6 snRNA-associated Sm-like protei...	97	0.005	37.7	28	46	GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005732; C:small nucleolar ribonucleoprotein complex; IPI:SGD.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005688; C:U6 snRNP; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.::GO:0000956; P:nuclear-transcribed mRNA catabolic process; TAS:SGD.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
15	Q9UUC6	97	SMD3_SCHPO Small nuclear ribonucleoprotein Sm...	99	0.009	37	25	41	GO:0000243; C:commitment complex; ISS:PomBase.::GO:0005685; C:U1 snRNP; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
									GO:0003729; F:mRNA binding; ISS:PomBase.
									GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
16	O94408	96	LSM2_SCHPO U6 snRNA-associated Sm-like protei...	108	0.029	35.4	27	49	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0005681; C:spliceosomal complex; NAS:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005688; C:U6 snRNP; ISS:PomBase.
									GO:0003723; F:RNA binding; ISS:PomBase.
									GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.
17	Q6BR90	85	LSM6_DEBHA U6 snRNA-associated Sm-like protei...	39	0.072	34.3	38	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
18	Q19952	123	LSM4_CAEEL Probable U6 snRNA-associated Sm-li...	43	0.75	32.3	40	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
19	P57743	89	LSM3_YEAST U6 snRNA-associated Sm-like protei...	95	0.75	31.6	24	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005732; C:small nucleolar ribonucleoprotein complex; IPI:SGD.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005688; C:U6 snRNP; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; TAS:SGD.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.::GO:0000956; P:nuclear-transcribed mRNA catabolic process; TAS:SGD.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
20	Q17348	136	SMD3_CAEEL Small nuclear ribonucleoprotein Sm...	98	1.1	32	27	36	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0043186; C:P granule; IDA:WormBase.
									GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.::GO:0032940; P:secretion by cell; IMP:WormBase.
21	P40070	187	LSM4_YEAST U6 snRNA-associated Sm-like protei...	95	2.1	31.6	27	41	GO:0000932; C:cytoplasmic mRNA processing body; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.::GO:0005732; C:small nucleolar ribonucleoprotein complex; IPI:SGD.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005688; C:U6 snRNP; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0017070; F:U6 snRNA binding; IMP:SGD.
									GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:SGD.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.::GO:0000956; P:nuclear-transcribed mRNA catabolic process; TAS:SGD.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
22	P62323	126	SMD3_XENLA Small nuclear ribonucleoprotein Sm...	111	2.6	30.8	23	35	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
23	P62320	126	SMD3_MOUSE Small nuclear ribonucleoprotein Sm...	111	2.6	30.8	23	35	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005683; C:U7 snRNP; ISS:UniProtKB.
									GO:0071208; F:histone pre-mRNA DCP binding; IDA:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
24	P62318	126	SMD3_HUMAN Small nuclear ribonucleoprotein Sm...	111	2.6	30.8	23	35	GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005689; C:U12-type spliceosomal complex; IDA:UniProtKB.::GO:0005683; C:U7 snRNP; IDA:UniProtKB.
									GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0071208; F:histone pre-mRNA DCP binding; ISS:UniProtKB.
									GO:0008334; P:histone mRNA metabolic process; TAS:Reactome.::GO:0034660; P:ncRNA metabolic process; TAS:Reactome.::GO:0000387; P:spliceosomal snRNP assembly; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
25	P43321	101	SMD3_YEAST Small nuclear ribonucleoprotein Sm...	98	3.3	30	26	37	GO:0000243; C:commitment complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005685; C:U1 snRNP; IDA:SGD.::GO:0071004; C:U2-type prespliceosome; IDA:SGD.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
									GO:0003729; F:mRNA binding; IPI:SGD.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
26	O14352	121	LSM4_SCHPO Probable U6 snRNA-associated Sm-li...	34	3.5	30.4	41	59	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.::GO:0005732; C:small nucleolar ribonucleoprotein complex; ISS:PomBase.::GO:0005681; C:spliceosomal complex; NAS:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005688; C:U6 snRNP; ISS:PomBase.
									GO:0003723; F:RNA binding; ISS:PomBase.
									GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.
27	Q9P5Z8	90	RUXF_NEUCR Probable small nuclear ribonucleop...	40	3.6	29.6	48	58	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
28	Q9QXA5	137	LSM4_MOUSE U6 snRNA-associated Sm-like protei...	98	3.8	30.4	27	41	GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005654; C:nucleoplasm; ISS:MGI.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
29	Q8SQH7	70	LSMH_ENCCU Probable U6 snRNA-associated Sm-li...	36	5.8	28.9	36	56	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30	Q9VXE0	76	RUXG_DROME Probable small nuclear ribonucleop...	56	6.2	28.9	29	55	GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.::GO:0030532; C:small nuclear ribonucleoprotein complex; IDA:FlyBase.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:FlyBase.
31	Q9Y4Z0	139	LSM4_HUMAN U6 snRNA-associated Sm-like protei...	98	6.2	30	27	41	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005688; C:U6 snRNP; TAS:ProtInc.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; TAS:ProtInc.

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