Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR063C
Length:
102
Number of sequences:
5887
Description:
YGR063C SPT4 SGDID:S000003295, Chr VII from 617824-617516, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in the regulating Pol I and Pol II transcription, pre-mRNA processing, kinetochore function, and gene silencing; forms a complex with Spt5p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32914    102   SPT4_YEAST Transcription elongation factor SP...1028e-72     215     100     100GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0032044; C:DSIF complex; IPI:SGD.
GO:0001181; F:core RNA polymerase I binding transcription factor activity; IC:SGD.::GO:0000991; F:core RNA polymerase II binding transcription factor activity; IC:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0000182; F:rDNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006325; P:chromatin organization; IMP:SGD.::GO:0006342; P:chromatin silencing; IMP:SGD.::GO:0007059; P:chromosome segregation; IMP:SGD.::GO:0008298; P:intracellular mRNA localization; IMP:SGD.::GO:0006370; P:mRNA capping; IGI:SGD.::GO:2001208; P:negative regulation of transcription elongation from RNA polymerase I promoter; IGI:SGD.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IMP:SGD.::GO:2001209; P:positive regulation of transcription elongation from RNA polymerase I promoter; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:2000232; P:regulation of rRNA processing; IMP:SGD.::GO:0090262; P:regulation of transcription-coupled nucleotide-excision repair; IGI:SGD.
2Q6FMX1    102   SPT4_CANGA Transcription elongation factor SP...1021e-65     199     93     95GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q752J8    102   SPT4_ASHGO Transcription elongation factor SP...1028e-63     192     86     93GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P81205    102   SPT4_KLULA Transcription elongation factor SP...1023e-59     183     78     92GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q5AK73    112   SPT4_CANAL Transcription elongation factor SP...1051e-27     102     49     63GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P0CR68    113   SPT4_CRYNJ Transcription elongation factor SP...1005e-26     99     42     67GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7P0CR69    113   SPT4_CRYNB Transcription elongation factor SP...1005e-26     99     42     67GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q6BHA5    111   SPT4_DEBHA Transcription elongation factor SP...1041e-24     95.1     45     63GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q7S743    120   SPT4_NEUCR Transcription elongation factor sp...1042e-23     92.4     45     56GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q6DGQ0    117   SPT4H_DANRE Transcription elongation factor S...993e-22     89     44     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q4R941    117   SPT4H_MACFA Transcription elongation factor S...993e-22     89     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12P63272    117   SPT4H_HUMAN Transcription elongation factor S...993e-22     89     43     59GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; TAS:ProtInc.::GO:0032785; P:negative regulation of transcription elongation, DNA-dependent; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0050434; P:positive regulation of viral transcription; TAS:Reactome.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
13Q3SYX6    117   SPT4H_BOVIN Transcription elongation factor S...993e-22     89     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
14P63271    117   SPT41_MOUSE Transcription elongation factor S...993e-22     89     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IMP:MGI.
15Q5HZ97    117   SPT4H_XENLA Transcription elongation factor S...994e-22     89     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q5RFH5    117   SPT4H_PONAB Transcription elongation factor S...995e-22     88.6     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17Q4WU00    156   SPT4_ASPFU Transcription elongation factor sp...888e-22     89     47     65GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q9Z199    117   SPT42_MOUSE Transcription elongation factor S...992e-21     86.7     43     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q4I5W5    99   SPT4_GIBZE Transcription elongation factor SP...959e-20     82     42     59GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q9P7K8    105   SPT4_SCHPO Transcription elongation factor sp...1033e-19     80.9     43     59GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0032044; C:DSIF complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; ISS:PomBase.
GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IGI:PomBase.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q9TVQ5    116   SPT4H_DROME Transcription elongation factor S...1022e-18     79     36     57GO:0005705; C:polytene chromosome interband; IDA:UniProtKB.::GO:0005703; C:polytene chromosome puff; IDA:UniProtKB.::GO:0008023; C:transcription elongation factor complex; IDA:FlyBase.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032785; P:negative regulation of transcription elongation, DNA-dependent; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.
22Q9TZ93    120   SPT4H_CAEEL Transcription elongation factor S...1034e-18     78.2     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23Q628A6    120   SPT4H_CAEBR Transcription elongation factor S...945e-17     75.5     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24Q94C60    116   SPT42_ARATH Transcription elongation factor S...860.00000000000005     67.4     36     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25Q8LCQ3    116   SPT41_ARATH Transcription elongation factor S...830.0000000000002     65.9     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032786; P:positive regulation of transcription elongation, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26P62045    348   NR1I3_PHOSI Nuclear receptor subfamily 1 grou...540.51     32.3     31     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27P62044    348   NR1I3_CALUR Nuclear receptor subfamily 1 grou...540.75     31.6     31     41GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28A2T7D9    348   NR1I3_PANTR Nuclear receptor subfamily 1 grou...541.1     31.2     30     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
29Q14994    352   NR1I3_HUMAN Nuclear receptor subfamily 1 grou...541.2     31.2     30     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.
GO:0004882; F:androgen receptor activity; TAS:ProtInc.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q2RHW0    423   SYH_MOOTA Histidine--tRNA ligase OS=Moorella ...271.6     30.8     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC.
GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro.
31Q8MIM3    352   NR1I3_MACMU Nuclear receptor subfamily 1 grou...532     30.4     30     43GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.::GO:0004887; F:thyroid hormone receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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