Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR060W
Length:
309
Number of sequences:
5887
Description:
YGR060W ERG25 SGDID:S000003292, Chr VII from 610564-611493, Genome Release 64-1-1, Verified ORF, "C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q618G2    300   C25HL_CAEBR Cholesterol 25-hydroxylase-like p...2280.000000000001     70.9     26     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
32Q8VYI1    260   SBH1_ARATH Sphingoid base hydroxylase 1 OS=Ar...1580.000000000009     67.4     32     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0000170; F:sphingosine hydroxylase activity; IGI:TAIR.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0046520; P:sphingoid biosynthetic process; IMP:TAIR.
33Q9AST3    259   SBH2_ARATH Sphingoid base hydroxylase 2 OS=Ar...1860.00000000004     65.5     30     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0000170; F:sphingosine hydroxylase activity; IGI:TAIR.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0046520; P:sphingoid biosynthetic process; IMP:TAIR.
34P38992    349   SUR2_YEAST Sphingolipid C4-hydroxylase SUR2 O...1630.0000000005     63.2     31     46GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0000170; F:sphingosine hydroxylase activity; IMP:SGD.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0006665; P:sphingolipid metabolic process; IMP:SGD.
35Q8J207    356   ERG3_LEPMC C-5 sterol desaturase OS=Leptospha...1660.00000002     58.9     26     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
36O75845    299   SC5D_HUMAN Lathosterol oxidase OS=Homo sapien...2080.00000009     56.2     25     43GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000248; F:C-5 sterol desaturase activity; TAS:ProtInc.::GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050046; F:lathosterol oxidase activity; IEA:EC.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
37O88822    299   SC5D_MOUSE Lathosterol oxidase OS=Mus musculu...1780.000005     50.8     24     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050046; F:lathosterol oxidase activity; IEA:EC.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
38Q7SBB6    344   ERG3_NEUCR Probable C-5 sterol desaturase OS=...1670.00003     48.9     26     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
39O94457    300   ERG31_SCHPO C-5 sterol desaturase erg31 OS=Sc...1690.0002     45.8     28     39GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.
GO:0000248; F:C-5 sterol desaturase activity; ISS:PomBase.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0006696; P:ergosterol biosynthetic process; IGI:PomBase.::GO:0090002; P:establishment of protein localization in plasma membrane; IMP:PomBase.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0071210; P:protein insertion into membrane raft; IMP:PomBase.
40P50860    364   ERG3_CANGA C-5 sterol desaturase OS=NRRL Y-65...1750.0005     45.1     25     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
41O93875    386   ERG3_CANAX C-5 sterol desaturase OS=Candida a...1720.001     44.3     26     40GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
42Q754B9    351   ERG3_ASHGO C-5 sterol desaturase OS=Y-1056) (...1670.003     42.7     26     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
43Q8NJ57    386   ERG3_CANDC C-5 sterol desaturase OS=3949 / NR...1490.004     42     26     39GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
44P32353    365   ERG3_YEAST C-5 sterol desaturase OS=Saccharom...1830.012     40.4     22     36GO:0005788; C:endoplasmic reticulum lumen; IDA:SGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0000248; F:C-5 sterol desaturase activity; IDA:SGD.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
45Q9M883    279   SC5D2_ARATH Putative Delta(7)-sterol-C5(6)-de...1600.088     37.7     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050046; F:lathosterol oxidase activity; IEA:EC.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
46Q39208    281   SC5D1_ARATH Delta(7)-sterol-C5(6)-desaturase ...1610.4     35.4     26     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050046; F:lathosterol oxidase activity; IEA:EC.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
47O13666    329   ERG32_SCHPO C-5 sterol desaturase erg32 OS=Sc...402.7     33.1     38     50GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0030176; C:integral to endoplasmic reticulum membrane; IC:PomBase.
GO:0000248; F:C-5 sterol desaturase activity; ISS:PomBase.::GO:0005506; F:iron ion binding; IEA:InterPro.
GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
48Q9ZT29    271   SC5D_TOBAC Delta(7)-sterol-C5(6)-desaturase O...1523.2     32.7     24     38GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0050046; F:lathosterol oxidase activity; IEA:EC.
GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW.
49P23662    381   CYB_CHLRE Cytochrome b OS=Chlamydomonas reinh...1526     32     26     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0022904; P:respiratory electron transport chain; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
50Q6AXB1    440   CF211_XENLA UPF0364 protein C6orf211 homolog ...896.4     32     26     47
51Q8H1Z0    632   WAX2_ARATH Protein WAX2 OS=Arabidopsis thalia...1838.6     32     22     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005506; F:iron ion binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
GO:0006723; P:cuticle hydrocarbon biosynthetic process; IMP:TAIR.::GO:0048235; P:pollen sperm cell differentiation; IMP:TAIR.::GO:0010025; P:wax biosynthetic process; IMP:TAIR.
records
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