Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR040W
Length:
368
Number of sequences:
5887
Description:
YGR040W KSS1 SGDID:S000003272, Chr VII from 575398-576504, Genome Release 64-1-1, Verified ORF, "Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
931O55173    559   PDPK1_RAT 3-phosphoinositide-dependent protei...2272e-18     90.1     28     51GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.
GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
932Q9UK32    745   KS6A6_HUMAN Ribosomal protein S6 kinase alpha...2520.00000000000001     79     26     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0045992; P:negative regulation of embryonic development; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:2000381; P:negative regulation of mesoderm development; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
933Q8BGW6    398   ST32A_MOUSE Serine/threonine-protein kinase 3...3152e-18     89     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
934Q9Z1J2    792   NEK4_MOUSE Serine/threonine-protein kinase Ne...3062e-18     90.1     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
935P33886    605   WIS1_SCHPO Protein kinase wis1 OS=Schizosacch...3102e-18     90.1     27     42GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; NAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; TAS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0043555; P:regulation of translation in response to stress; IMP:PomBase.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; TAS:PomBase.
936Q60EY8    466   CIPKK_ORYSJ CBL-interacting protein kinase 20...3192e-18     89.7     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
937P10666    629   KS6AB_XENLA Ribosomal protein S6 kinase 2 bet...2520.0000000000008     73.2     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
938Q9Y2U5    619   M3K2_HUMAN Mitogen-activated protein kinase k...2242e-18     89.7     27     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
939Q10SC8    456   CIPK9_ORYSJ CBL-interacting protein kinase 9 ...2162e-18     89.4     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
940A7F0W2    951   ATG1_SCLS1 Serine/threonine-protein kinase AT...3532e-18     90.1     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
941Q2RBF0    434   CIPKF_ORYSJ CBL-interacting protein kinase 15...2213e-18     89.4     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
942Q66I46    466   MKNK2_XENTR MAP kinase-interacting serine/thr...3063e-18     89.4     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
943Q9SJ61    520   CDPKP_ARATH Calcium-dependent protein kinase ...3313e-18     89.4     26     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
944Q9MAM1    447   CIPK9_ARATH CBL-interacting serine/threonine-...2163e-18     89     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051365; P:cellular response to potassium ion starvation; IMP:TAIR.::GO:0043266; P:regulation of potassium ion transport; IMP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0010555; P:response to mannitol stimulus; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
945A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...3043e-18     89.4     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
946Q03497    939   STE20_YEAST Serine/threonine-protein kinase S...2573e-18     89.7     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:SGD.
GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0010629; P:negative regulation of gene expression; IMP:SGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:SGD.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:SGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:SGD.::GO:0007124; P:pseudohyphal growth; IMP:SGD.::GO:0007096; P:regulation of exit from mitosis; IMP:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD.::GO:0035376; P:sterol import; IMP:SGD.::GO:0034063; P:stress granule assembly; IMP:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.
947A6ZU08    560   TOS3_YEAS7 Serine/threonine-protein kinase TO...3283e-18     89.4     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
948Q9ES70    313   NEK6_MOUSE Serine/threonine-protein kinase Ne...2323e-18     87.4     30     50GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.
949P43637    560   TOS3_YEAST Serine/threonine-protein kinase TO...3283e-18     89.4     29     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0006006; P:glucose metabolic process; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
950Q2QYM3    439   CIPKE_ORYSJ CBL-interacting protein kinase 14...2213e-18     89     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
951Q6ZLP5    450   CIPKN_ORYSJ CBL-interacting protein kinase 23...3274e-18     89     30     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
952B4J3F1    762   PLK4_DROGR Serine/threonine-protein kinase PL...3084e-18     89.4     26     45GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
953Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...2204e-18     89     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
954Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...3114e-18     89     27     45GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
955Q55DD4    1678   PAKD_DICDI Serine/threonine-protein kinase pa...3224e-18     89.7     26     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
956Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...3004e-18     89     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
957P0CY23    1230   STE20_CANAX Serine/threonine-protein kinase C...2434e-18     89.7     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
958Q9Z2A0    559   PDPK1_MOUSE 3-phosphoinositide-dependent prot...2274e-18     89     27     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB.
959P59895    313   NEK6_RAT Serine/threonine-protein kinase Nek6...2214e-18     87     31     50GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; ISS:UniProtKB.
960P0CY24    1228   STE20_CANAL Serine/threonine-protein kinase C...2434e-18     89.7     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0001410; P:chlamydospore formation; IMP:CGD.::GO:0000747; P:conjugation with cellular fusion; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0000165; P:MAPK cascade; IGI:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0001558; P:regulation of cell growth; IGI:CGD.
961P52564    334   MP2K6_HUMAN Dual specificity mitogen-activate...3094e-18     87.4     27     44GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0006975; P:DNA damage induced protein phosphorylation; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
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