Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR040W
Length:
368
Number of sequences:
5887
Description:
YGR040W KSS1 SGDID:S000003272, Chr VII from 575398-576504, Genome Release 64-1-1, Verified ORF, "Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511P08181    336   CSK2A_DROME Casein kinase II subunit alpha OS...3221e-30     124     30     49GO:0005829; C:cytosol; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005956; C:protein kinase CK2 complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0022416; P:chaeta development; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0046331; P:lateral inhibition; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; IMP:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:FlyBase.::GO:0007228; P:positive regulation of hh target transcription factor activity; IMP:FlyBase.::GO:0045880; P:positive regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IDA:FlyBase.
512Q4V793    616   HIPK4_RAT Homeodomain-interacting protein kin...3581e-30     126     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
513Q4P9T2    654   SSN3_USTMA Serine/threonine-protein kinase SS...3102e-30     126     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
514Q8TG13    336   CSK2A_NEUCR Casein kinase II subunit alpha OS...3312e-30     123     29     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
515Q3V016    616   HIPK4_MOUSE Homeodomain-interacting protein k...3592e-30     125     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
516O54833    350   CSK22_MOUSE Casein kinase II subunit alpha' O...3202e-30     123     30     52GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
517P20427    350   CSK22_BOVIN Casein kinase II subunit alpha' O...3203e-30     123     30     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
518Q8JH47    464   CDK8_DANRE Cyclin-dependent kinase 8 OS=Danio...3203e-30     124     32     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
519P68400    391   CSK21_HUMAN Casein kinase II subunit alpha OS...3194e-30     123     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0016581; C:NuRD complex; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; TAS:ProtInc.::GO:0016580; C:Sin3 complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051879; F:Hsp90 protein binding; TAS:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0061077; P:chaperone-mediated protein folding; TAS:UniProtKB.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
520P68399    391   CSK21_BOVIN Casein kinase II subunit alpha OS...3194e-30     123     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:AgBase.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
521Q60737    391   CSK21_MOUSE Casein kinase II subunit alpha OS...3194e-30     123     30     50GO:0005956; C:protein kinase CK2 complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0019888; F:protein phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
522P21868    391   CSK21_CHICK Casein kinase II subunit alpha OS...3194e-30     123     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
523P19139    391   CSK21_RAT Casein kinase II subunit alpha OS=R...3194e-30     123     30     50GO:0005956; C:protein kinase CK2 complex; TAS:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:RGD.::GO:0042127; P:regulation of cell proliferation; NAS:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
524O76484    353   CSK2A_SPOFR Casein kinase II subunit alpha OS...3084e-30     122     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
525Q8WP28    616   HIPK4_MACFA Homeodomain-interacting protein k...3595e-30     125     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
526Q55FT4    2247   TSUA_DICDI Probable serine/threonine-protein ...3065e-30     127     32     46GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase.
527P19784    350   CSK22_HUMAN Casein kinase II subunit alpha' O...3205e-30     122     29     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
528Q54V83    460   Y9296_DICDI Probable serine/threonine-protein...3566e-30     123     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
529Q9NR20    520   DYRK4_HUMAN Dual specificity tyrosine-phospho...3446e-30     123     28     49GO:0005794; C:Golgi apparatus; IDA:HPA.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
530P28020    392   CSK21_XENLA Casein kinase II subunit alpha OS...3197e-30     122     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
531P0C661    612   CDK8_CAEBR Cyclin-dependent kinase 8 OS=Caeno...3678e-30     124     29     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
532Q6BM25    472   SSN3_DEBHA Serine/threonine-protein kinase SS...2779e-30     122     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
533Q9BWU1    502   CDK19_HUMAN Cyclin-dependent kinase 19 OS=Hom...3291e-29     122     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
534Q8BWD8    501   CDK19_MOUSE Cyclin-dependent kinase 19 OS=Mus...3291e-29     122     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
535Q8R3L8    464   CDK8_MOUSE Cyclin-dependent kinase 8 OS=Mus m...3201e-29     122     32     48GO:0016592; C:mediator complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
536Q08466    403   CSK22_ARATH Casein kinase II subunit alpha-2 ...2501e-29     121     30     54GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
537Q4FCZ5    450   SSN3_GIBMO Serine/threonine-protein kinase SS...3702e-29     121     26     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
538P18334    360   CSK2A_CAEEL Casein kinase II subunit alpha OS...2612e-29     120     30     53GO:0030424; C:axon; IDA:UniProtKB.::GO:0005929; C:cilium; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0034606; P:response to hermaphrodite contact; IMP:WormBase.::GO:0034608; P:vulval location; IMP:WormBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
539Q8BI55    632   DYRK4_MOUSE Dual specificity tyrosine-phospho...3672e-29     123     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.
540P33674    391   CSK21_RABIT Casein kinase II subunit alpha OS...3192e-29     120     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071174; P:mitotic cell cycle spindle checkpoint; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
541P49336    464   CDK8_HUMAN Cyclin-dependent kinase 8 OS=Homo ...3202e-29     121     32     47GO:0016592; C:mediator complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
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