UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR012W

Length:

393

Number of sequences:

5887

Description:

YGR012W YGR012W SGDID:S000003244, Chr VII from 513159-514340, Genome Release 64-1-1, Verified ORF, "Putative cysteine synthase, localized to the mitochondrial outer membrane"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q79FV4	372	Y848_MYCTU Uncharacterized pyridoxal phosphat...	338	0.00000003	58.9	25	42	GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005829; C:cytosol; TAS:Reactome.
									GO:0004124; F:cysteine synthase activity; TAS:Reactome.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006535; P:cysteine biosynthetic process from serine; TAS:Reactome.
92	A6ZVB1	338	SDHL_YEAS7 L-serine dehydratase OS=Saccharomy...	221	0.00000005	57.8	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
93	C8ZAU6	338	SDHL_YEAS8 L-serine dehydratase OS=(Baker's y...	221	0.00000005	57.8	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
94	B3LU13	338	SDHL_YEAS1 L-serine dehydratase OS=Saccharomy...	221	0.00000005	57.8	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
95	P0CF23	338	SDH1_YEASX L-serine dehydratase OS=Saccharomy...	222	0.0000001	56.6	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
96	P55664	332	Y4TJ_RHISN Putative threonine dehydratase OS=...	119	0.0000008	53.9	35	50
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
97	Q9GZT4	340	SRR_HUMAN Serine racemase OS=Homo sapiens (Hu...	214	0.0001	47	25	43	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0016594; F:glycine binding; ISS:UniProtKB.::GO:0003941; F:L-serine ammonia-lyase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0030378; F:serine racemase activity; IDA:UniProtKB.::GO:0018114; F:threonine racemase activity; ISS:UniProtKB.
									GO:0070179; P:D-serine biosynthetic process; IDA:UniProtKB.::GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0042866; P:pyruvate biosynthetic process; IDA:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IEP:UniProtKB.
98	Q9K7E3	354	THRC_BACHD Threonine synthase OS=9153 / C-125...	109	0.0004	45.8	33	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
99	P09123	352	THRC_BACSL Threonine synthase OS=Bacillus sp....	117	0.0004	45.4	32	48
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
100	Q54HH2	324	SRR_DICDI Probable serine racemase OS=Dictyos...	225	0.0006	45.1	27	42
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
101	Q58860	405	THRC_METJA Threonine synthase OS=JCM 10045 / ...	293	0.0008	44.7	27	39
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
102	Q39469	590	THD1_CICAR Threonine dehydratase biosynthetic...	209	0.002	43.9	30	42	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
103	P0CF21	127	SDH1_YEAST Truncated L-serine dehydratase OS=...	108	0.007	39.7	26	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
104	Q76EQ0	333	SRR_RAT Serine racemase OS=Rattus norvegicus ...	123	0.009	41.2	25	49	GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0030378; F:serine racemase activity; IDA:UniProtKB.
									GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.
105	A0JNI4	334	SRR_BOVIN Serine racemase OS=Bos taurus (Bovi...	203	0.01	41.2	25	42
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0030378; F:serine racemase activity; ISS:UniProtKB.
									GO:0006563; P:L-serine metabolic process; ISS:UniProtKB.
106	P04990	352	THRC_BACSU Threonine synthase OS=Bacillus sub...	48	0.014	40.8	40	60
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
107	Q04513	436	ILVA_CORGL L-threonine dehydratase biosynthet...	112	0.02	40.4	29	46
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006566; P:threonine metabolic process; ISS:UniProtKB.
108	O94634	600	THDH_SCHPO Threonine dehydratase, mitochondri...	109	0.023	40.4	30	49	GO:0005739; C:mitochondrion; ISS:PomBase.
									GO:0004794; F:L-threonine ammonia-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; ISS:PomBase.
109	Q03DF6	432	SDHD_PEDPA Probable D-serine dehydratase OS=P...	250	0.028	40	24	41
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
110	P25306	595	THD1_SOLLC Threonine dehydratase biosynthetic...	265	0.03	40	25	41	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
111	Q8VBT2	327	SDHL_MOUSE L-serine dehydratase/L-threonine d...	157	0.031	39.7	25	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
112	P66902	360	THRC_MYCTU Threonine synthase OS=Mycobacteriu...	40	0.035	39.7	50	63	GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0042803; F:protein homodimerization activity; IPI:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IDA:MTBBASE.::GO:0004795; F:threonine synthase activity; IDA:MTBBASE.
									GO:0040007; P:growth; IMP:MTBBASE.::GO:0009088; P:threonine biosynthetic process; IMP:MTBBASE.
113	P66903	360	THRC_MYCBO Threonine synthase OS=Mycobacteriu...	40	0.035	39.7	50	63
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
114	Q75TC9	441	SDHD_GEOKA Probable D-serine dehydratase OS=G...	167	0.038	39.7	29	44
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
115	Q2T8Q2	444	SDHD_BURTA Probable D-serine dehydratase OS=C...	152	0.043	39.7	26	42
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
116	A0KMD0	397	TRPB_AERHH Tryptophan synthase beta chain OS=...	352	0.071	38.9	20	38
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
117	Q9KC12	442	SDHD_BACHD Probable D-serine dehydratase OS=9...	255	0.083	38.5	19	40
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
118	Q9ZSS6	592	THD1_ARATH Threonine dehydratase biosynthetic...	102	0.088	38.5	32	49	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004794; F:L-threonine ammonia-lyase activity; IMP:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; TAS:TAIR.
119	A4SKT1	397	TRPB_AERS4 Tryptophan synthase beta chain OS=...	347	0.099	38.1	20	39
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
120	Q9QZX7	339	SRR_MOUSE Serine racemase OS=Mus musculus (Mo...	128	0.12	37.7	27	45
									GO:0005524; F:ATP binding; IDA:MGI.::GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0016594; F:glycine binding; IDA:MGI.::GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0030170; F:pyridoxal phosphate binding; IMP:MGI.::GO:0030378; F:serine racemase activity; IDA:MGI.::GO:0018114; F:threonine racemase activity; IDA:MGI.
									GO:0070179; P:D-serine biosynthetic process; IDA:MGI.::GO:0006563; P:L-serine metabolic process; IDA:MGI.::GO:0051289; P:protein homotetramerization; IDA:MGI.
121	P45837	360	THRC_MYCLE Threonine synthase OS=Mycobacteriu...	40	0.15	37.7	48	60
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.

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