Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR003W
Length:
744
Number of sequences:
5887
Description:
YGR003W CUL3 SGDID:S000003235, Chr VII from 500132-502366, Genome Release 64-1-1, Verified ORF, "Ubiquitin-protein ligase, forms a complex with Elc1p that polyubiquitylates monoubiquitylated RNA polymerase II to trigger its proteolysis; cullin family member with similarity to Cdc53p and human CUL3"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q5RCF3    745   CUL2_PONAB Cullin-2 OS=Pongo abelii (Sumatran...3703e-27     121     26     49GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
32Q13617    745   CUL2_HUMAN Cullin-2 OS=Homo sapiens (Human). ...3703e-27     121     26     49GO:0031462; C:Cul2-RING ubiquitin ligase complex; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
33O14122    734   CUL4_SCHPO Cullin-4 OS=Schizosaccharomyces po...7203e-26     118     23     43GO:0043494; C:CLRC ubiquitin ligase complex; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031618; C:nuclear centromeric heterochromatin; TAS:PomBase.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0030702; P:chromatin silencing at centromere; IMP:PomBase.::GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0006348; P:chromatin silencing at telomere; IMP:PomBase.::GO:0031048; P:chromatin silencing by small RNA; IMP:PomBase.::GO:0007535; P:donor selection; TAS:PomBase.::GO:0031507; P:heterochromatin assembly; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0045836; P:positive regulation of meiosis; IGI:PomBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:PomBase.::GO:0051570; P:regulation of histone H3-K9 methylation; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:PomBase.
34P0CH31    721   CLL1_ARATH Putative cullin-like protein 1 OS=...3984e-25     115     26     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
35Q21346    729   CUL6_CAEEL Cullin-6 OS=Caenorhabditis elegans...7613e-24     112     21     43GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
36Q54XF7    750   CUL5_DICDI Cullin-5 OS=Dictyostelium discoide...3792e-23     109     28     48GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
37Q17389    780   CUL1_CAEEL Cullin-1 OS=Caenorhabditis elegans...3701e-22     107     26     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:WormBase.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008361; P:regulation of cell size; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
38Q12018    815   CDC53_YEAST Cell division control protein 53 ...8415e-20     99     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD.
GO:0003688; F:DNA replication origin binding; IPI:SGD.::GO:0030674; F:protein binding, bridging; IMP:SGD.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.
39Q23639    765   CUL5_CAEEL Cullin-5 OS=Caenorhabditis elegans...3910.00000000000002     80.5     23     45GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0006468; P:protein phosphorylation; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006974; P:response to DNA damage stimulus; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
40Q93034    780   CUL5_HUMAN Cullin-5 OS=Homo sapiens (Human). ...3920.00000000000004     79.7     25     46GO:0031466; C:Cul5-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005262; F:calcium channel activity; TAS:ProtInc.::GO:0004872; F:receptor activity; TAS:ProtInc.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0016032; P:viral reproduction; TAS:Reactome.
41Q5RB36    780   CUL5_PONAB Cullin-5 OS=Pongo abelii (Sumatran...3920.00000000000006     79.3     25     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
42Q9JJ31    780   CUL5_RAT Cullin-5 OS=Rattus norvegicus (Rat)....3920.00000000000006     79.3     25     46GO:0031466; C:Cul5-RING ubiquitin ligase complex; TAS:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:RGD.::GO:0005000; F:vasopressin receptor activity; TAS:RGD.
GO:0051480; P:cytosolic calcium ion homeostasis; IMP:RGD.::GO:0000209; P:protein polyubiquitination; TAS:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
43Q9D5V5    780   CUL5_MOUSE Cullin-5 OS=Mus musculus (Mouse). ...3920.0000000000002     77.8     24     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
44Q29425    780   CUL5_RABIT Cullin-5 OS=Oryctolagus cuniculus ...3920.0000000000002     77.4     25     46GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
45Q8H1U5    865   APC2_ARATH Anaphase-promoting complex subunit...1940.00003     51.2     23     45GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0009561; P:megagametogenesis; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
46Q9UJX6    822   ANC2_HUMAN Anaphase-promoting complex subunit...1940.0002     48.5     24     43GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; TAS:ProtInc.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.
47Q8BZQ7    837   ANC2_MOUSE Anaphase-promoting complex subunit...1900.002     45.4     22     43GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
48Q05156    746   GUN1_STRRE Cellulase 1 OS=Streptomyces reticu...511     36.6     29     53
GO:0008810; F:cellulase activity; IEA:EC.
GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
49Q895K2    1427   DPO3_CLOTE DNA polymerase III polC-type OS=Cl...1761.6     35.8     19     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
50Q9XIE8    255   CLL3_ARATH Cullin-like protein 3 OS=Arabidops...2624.3     33.9     21     42GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
51A0Q5P9    906   SECA_FRATN Protein translocase subunit SecA O...1346.5     33.9     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0017038; P:protein import; IEA:InterPro.::GO:0006605; P:protein targeting; IEA:InterPro.
52P29733    254   PYG3_MASLA Phycobilisome rod-core linker poly...1636.6     33.1     25     45GO:0030089; C:phycobilisome; IEA:UniProtKB-KW.
GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
53Q2A2E3    906   SECA_FRATH Protein translocase subunit SecA O...1347.9     33.5     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0017038; P:protein import; IEA:InterPro.::GO:0006605; P:protein targeting; IEA:InterPro.
54A7NDG7    906   SECA_FRATF Protein translocase subunit SecA O...1347.9     33.5     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0017038; P:protein import; IEA:InterPro.::GO:0006605; P:protein targeting; IEA:InterPro.
55A4IZ46    906   SECA_FRATW Protein translocase subunit SecA O...1349.8     33.5     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0017038; P:protein import; IEA:InterPro.::GO:0006605; P:protein targeting; IEA:InterPro.
records
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