| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53057 | 165 | YPS5_YEAST Yapsin-5 OS=Saccharomyces cerevisi... | 165 | 4e-116 | 333 | 100 | 100 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 2 | P40583 | 537 | YPS6_YEAST Aspartic proteinase yapsin-6 OS=Sa... | 116 | 2e-65 | 214 | 93 | 94 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | P32329 | 569 | YPS1_YEAST Aspartic proteinase 3 OS=Saccharom... | 125 | 0.00000002 | 56.6 | 38 | 52 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0016485; P:protein processing; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | D4DFT3 | 495 | OPSB_TRIVH Probable aspartic-type endopeptida... | 101 | 0.0000002 | 52.8 | 30 | 53 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 5 | D4AIS3 | 495 | OPSB_ARTBC Probable aspartic-type endopeptida... | 101 | 0.0000003 | 52.4 | 31 | 53 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 6 | P53379 | 596 | MKC7_YEAST Aspartic proteinase MKC7 OS=Saccha... | 35 | 0.00006 | 45.8 | 54 | 74 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0009277; C:fungal-type cell wall; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0006508; P:proteolysis; IMP:SGD. | 7 | Q12303 | 508 | YPS3_YEAST Aspartic proteinase yapsin-3 OS=Sa... | 103 | 0.0006 | 42.7 | 32 | 48 | GO:0046658; C:anchored to plasma membrane; IPI:SGD. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0044267; P:cellular protein metabolic process; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 8 | Q6IE75 | 514 | BACE2_RAT Beta-secretase 2 OS=Rattus norvegic... | 82 | 0.002 | 41.2 | 34 | 54 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB. | 9 | O13340 | 425 | CARP_PODAS Podosporapepsin OS=Podospora anser... | 28 | 0.004 | 40 | 64 | 75 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q9S9K4 | 475 | ASPL2_ARATH Aspartic proteinase-like protein ... | 41 | 0.008 | 39.3 | 32 | 66 | GO:0046658; C:anchored to plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q29079 | 420 | PAG2_PIG Pregnancy-associated glycoprotein 2 ... | 40 | 0.018 | 38.1 | 50 | 63 | GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 12 | Q9JL18 | 514 | BACE2_MOUSE Beta-secretase 2 OS=Mus musculus ... | 83 | 0.033 | 37.7 | 35 | 55 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB. | 13 | Q8NKB6 | 487 | OPSB_ASPOR Probable aspartic-type endopeptida... | 38 | 0.038 | 37.4 | 45 | 63 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 14 | Q4WDN4 | 485 | OPSB_ASPFU Probable aspartic-type endopeptida... | 51 | 0.04 | 37.4 | 37 | 55 | GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | P56817 | 501 | BACE1_HUMAN Beta-secretase 1 OS=Homo sapiens ... | 30 | 0.066 | 36.6 | 50 | 73 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0008798; F:beta-aspartyl-peptidase activity; TAS:ProtInc.::GO:0019899; F:enzyme binding; IPI:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; TAS:UniProtKB. | 16 | P56819 | 501 | BACE1_RAT Beta-secretase 1 OS=Rattus norvegic... | 30 | 0.072 | 36.6 | 50 | 73 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 17 | P56818 | 501 | BACE1_MOUSE Beta-secretase 1 OS=Mus musculus ... | 30 | 0.072 | 36.6 | 50 | 73 | GO:0030424; C:axon; IDA:MGI.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 18 | P11838 | 419 | CARP_CRYPA Endothiapepsin OS=parasitica). GN=... | 28 | 0.078 | 36.6 | 54 | 71 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 19 | D4DEN7 | 400 | CARP_TRIVH Probable vacuolar protease A OS=Tr... | 39 | 0.084 | 36.2 | 46 | 64 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 20 | D4B385 | 400 | CARP_ARTBC Probable vacuolar protease A OS=(T... | 39 | 0.084 | 36.2 | 46 | 64 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 21 | C5FS55 | 395 | CARP_ARTOC Vacuolar protease A OS=canis). GN=... | 39 | 0.085 | 36.2 | 46 | 64 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 22 | Q2HJ40 | 501 | BACE1_BOVIN Beta-secretase 1 OS=Bos taurus (B... | 30 | 0.091 | 36.2 | 50 | 73 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 23 | Q9LS40 | 500 | ASPG1_ARATH Protein ASPARTIC PROTEASE IN GUAR... | 82 | 0.095 | 36.2 | 30 | 48 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR. | 24 | O42630 | 398 | CARP_ASPFU Vacuolar protease A OS=A1100) (Asp... | 54 | 0.11 | 35.8 | 37 | 59 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005775; C:vacuolar lumen; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | Q9N2D2 | 381 | CHYM_CALJA Chymosin OS=Callithrix jacchus (Wh... | 39 | 0.13 | 35.8 | 46 | 62 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 26 | P27823 | 388 | PEPAF_RABIT Pepsin F OS=Oryctolagus cuniculus... | 56 | 0.14 | 35.8 | 41 | 59 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 27 | P12630 | 587 | BAR1_YEAST Barrierpepsin OS=Saccharomyces cer... | 46 | 0.22 | 35 | 35 | 61 | GO:0030287; C:cell wall-bounded periplasmic space; TAS:SGD.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IDA:SGD. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IDA:SGD.::GO:0043171; P:peptide catabolic process; IDA:SGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | Q1KLR6 | 473 | BACE1_CAVPO Beta-secretase 1 OS=Cavia porcell... | 30 | 0.22 | 35 | 50 | 73 | GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB. | 29 | P18276 | 381 | CHYM_SHEEP Chymosin OS=Ovis aries (Sheep). GN... | 37 | 0.24 | 35 | 49 | 59 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P00794 | 381 | CHYM_BOVIN Chymosin OS=Bos taurus (Bovine). G... | 37 | 0.25 | 35 | 49 | 59 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007586; P:digestion; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | Q9LHE3 | 470 | ASPG2_ARATH Protein ASPARTIC PROTEASE IN GUAR... | 45 | 0.25 | 35 | 33 | 53 | | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
