Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL254W
Length:
299
Number of sequences:
5887
Description:
YGL254W FZF1 SGDID:S000003223, Chr VII from 22304-23203, Genome Release 64-1-1, Verified ORF, "Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32805    299   FZF1_YEAST Zinc finger protein FZF1 OS=Saccha...2990     625     100     100GO:0005634; C:nucleus; IC:SGD.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IMP:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061426; P:positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
2P39933    429   TF3A_YEAST Transcription factor IIIA OS=Sacch...880.00000000000005     75.1     42     60GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001002; F:RNA polymerase III type 1 promoter sequence-specific DNA binding; IDA:SGD.::GO:0001152; F:RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity; IDA:SGD.::GO:0001156; F:TFIIIC-class transcription factor binding; IC:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
3P79958    407   WT1B_XENLA Wilms tumor protein homolog B OS=X...920.000000000001     70.9     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
4Q9Y5W3    355   KLF2_HUMAN Krueppel-like factor 2 OS=Homo sap...890.000000000001     71.2     38     54GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5B5DE03    413   WT1_XENTR Wilms tumor protein homolog OS=Xeno...920.000000000002     70.9     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
6Q60793    483   KLF4_MOUSE Krueppel-like factor 4 OS=Mus musc...890.000000000004     69.7     37     52
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009913; P:epidermal cell differentiation; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
7Q9ET58    351   KLF2_RAT Krueppel-like factor 2 OS=Rattus nor...890.000000000004     69.3     37     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0071347; P:cellular response to interleukin-1; IEP:RGD.::GO:0071356; P:cellular response to tumor necrosis factor; IEP:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IMP:RGD.::GO:0034616; P:response to laminar fluid shear stress; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q60843    354   KLF2_MOUSE Krueppel-like factor 2 OS=Mus musc...890.000000000005     69.3     37     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0043249; P:erythrocyte maturation; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q07243    675   MTF1_MOUSE Metal regulatory transcription fac...950.000000000005     69.7     34     57GO:0005634; C:nucleus; IC:MGI.
GO:0035035; F:histone acetyltransferase binding; IPI:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0046686; P:response to cadmium ion; IMP:MGI.::GO:0006979; P:response to oxidative stress; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10O43474    513   KLF4_HUMAN Krueppel-like factor 4 OS=Homo sap...890.000000000006     69.3     37     52GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.::GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.::GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
11Q14872    753   MTF1_HUMAN Metal regulatory transcription fac...950.000000000008     69.3     34     57GO:0005634; C:nucleus; IDA:HPA.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q90WR8    771   SP3_CHICK Transcription factor Sp3 OS=Gallus ...930.000000000008     68.9     34     56GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q02447    781   SP3_HUMAN Transcription factor Sp3 OS=Homo sa...990.000000000009     68.9     34     57GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
14O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...1960.000000000009     68.9     28     45GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
15Q8TDD2    431   SP7_HUMAN Transcription factor Sp7 OS=Homo sa...1400.00000000002     67.4     31     43GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0017151; F:DEAD/H-box RNA helicase binding; ISS:BHF-UCL.::GO:0003677; F:DNA binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001649; P:osteoblast differentiation; ISS:BHF-UCL.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16O62651    449   WT1_PIG Wilms tumor protein homolog OS=Sus sc...1000.00000000003     67     40     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
17Q8VI67    428   SP7_MOUSE Transcription factor Sp7 OS=Mus mus...1150.00000000003     67.4     33     45GO:0005634; C:nucleus; IDA:MGI.
GO:0017151; F:DEAD/H-box RNA helicase binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18P22561    449   WT1_MOUSE Wilms tumor protein homolog OS=Mus ...950.00000000004     66.6     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; IMP:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:UniProtKB.::GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0060923; P:cardiac muscle cell fate commitment; IMP:BHF-UCL.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060976; P:coronary vasculature development; TAS:DFLAT.::GO:0060539; P:diaphragm development; IMP:UniProtKB.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; IMP:UniProtKB.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0060231; P:mesenchymal to epithelial transition; IMP:UniProtKB.::GO:0001823; P:mesonephros development; IMP:MGI.::GO:0072278; P:metanephric comma-shaped body morphogenesis; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; IMP:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; IMP:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; IMP:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; IMP:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072166; P:posterior mesonephric tubule development; IMP:UniProtKB.::GO:0003156; P:regulation of organ formation; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IDA:UniProtKB.::GO:0007530; P:sex determination; IMP:MGI.::GO:0007356; P:thorax and anterior abdomen determination; IMP:UniProtKB.::GO:0009888; P:tissue development; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI.::GO:0061032; P:visceral serous pericardium development; IMP:UniProtKB.
19P49952    448   WT1_RAT Wilms tumor protein homolog OS=Rattus...950.00000000005     66.6     39     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
20P19544    449   WT1_HUMAN Wilms tumor protein OS=Homo sapiens...950.00000000005     66.6     39     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0060923; P:cardiac muscle cell fate commitment; ISS:BHF-UCL.::GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IGI:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IGI:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; IDA:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; IGI:UniProtKB.
21Q91660    1569   GLI3_XENLA Zinc finger protein GLI3 OS=Xenopu...880.00000000005     67     40     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22B7ZSG3    414   WT1A_XENLA Wilms tumor protein homolog A OS=X...950.00000000007     65.9     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072013; P:glomus development; IMP:UniProtKB.::GO:1900207; P:negative regulation of pronephric nephron tubule development; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:UniProtKB.::GO:0039004; P:specification of pronephric proximal tubule identity; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
23P50902    288   WT1_ALLMI Wilms tumor protein homolog OS=Alli...950.00000000009     64.7     39     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0008406; P:gonad development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
24P49953    239   WT1_SMIMA Wilms tumor protein homolog OS=Smin...950.0000000001     63.9     39     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0008406; P:gonad development; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
25Q9BSK1    485   ZN577_HUMAN Zinc finger protein 577 OS=Homo s...1640.0000000001     65.1     31     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q62521    466   ZIC3_MOUSE Zinc finger protein ZIC 3 OS=Mus m...990.0000000006     63.2     33     52GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035545; P:determination of left/right asymmetry in nervous system; IMP:UniProtKB.::GO:0001947; P:heart looping; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27O60481    467   ZIC3_HUMAN Zinc finger protein ZIC 3 OS=Homo ...990.0000000006     63.2     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q6DJQ6    441   ZIC3_XENTR Zinc finger protein ZIC 3 OS=Xenop...990.000000001     62     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007368; P:determination of left/right symmetry; ISS:UniProtKB.::GO:0000578; P:embryonic axis specification; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014034; P:neural crest cell fate commitment; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29O57311    441   ZIC3_XENLA Zinc finger protein ZIC 3 OS=Xenop...990.000000001     62.4     33     52GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.::GO:0000578; P:embryonic axis specification; IMP:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014034; P:neural crest cell fate commitment; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30Q8N143    479   BCL6B_HUMAN B-cell CLL/lymphoma 6 member B pr...830.000000001     62.4     40     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
31Q6NUN9    644   ZN746_HUMAN Zinc finger protein 746 OS=Homo s...850.000000001     62.4     34     55GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0010941; P:regulation of cell death; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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