Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL253W
Length:
486
Number of sequences:
5887
Description:
YGL253W HXK2 SGDID:S000003222, Chr VII from 23935-25395, Genome Release 64-1-1, Verified ORF, "Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P04807    486   HXKB_YEAST Hexokinase-2 OS=Saccharomyces cere...4860     1003     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:SGD.
GO:0032445; P:fructose import; IGI:SGD.::GO:0006000; P:fructose metabolic process; IMP:SGD.::GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0046015; P:regulation of transcription by glucose; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
2P04806    485   HXKA_YEAST Hexokinase-1 OS=Saccharomyces cere...4860     782     77     89GO:0005829; C:cytosol; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:SGD.
GO:0032445; P:fructose import; IGI:SGD.::GO:0006000; P:fructose metabolic process; IMP:SGD.::GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD.
3P33284    485   HXK_KLULA Hexokinase OS=1267 / NRRL Y-1140 / ...4850     767     73     86
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
4P83776    484   HXKB_CANAL Hexokinase-2 OS=Candida albicans (...4870     707     70     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
5P50506    478   HXK_SCHOC Hexokinase OS=Schwanniomyces occide...4780     685     70     82
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
6P80581    490   HXK_EMENI Hexokinase OS=194 / M139) (Aspergil...4860     550     55     73
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
7Q09756    484   HXK1_SCHPO Hexokinase-1 OS=Schizosaccharomyce...4712e-154     455     49     66GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase.
GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IC:PomBase.::GO:0006013; P:mannose metabolic process; IDA:PomBase.::GO:0009051; P:pentose-phosphate shunt, oxidative branch; TAS:PomBase.
8Q92407    495   HXKG_ASPNG Glucokinase OS=Aspergillus niger. ...4932e-86     281     37     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
9P17709    500   HXKG_YEAST Glucokinase-1 OS=Saccharomyces cer...4928e-86     279     37     52GO:0005829; C:cytosol; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IDA:SGD.
GO:0006096; P:glycolysis; IDA:SGD.::GO:0006013; P:mannose metabolic process; IDA:SGD.
10P50521    455   HXK2_SCHPO Hexokinase-2 OS=Schizosaccharomyce...4584e-84     273     37     53GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:PomBase.::GO:0004340; F:glucokinase activity; IDA:PomBase.::GO:0019158; F:mannokinase activity; IDA:PomBase.
GO:0006002; P:fructose 6-phosphate metabolic process; IDA:PomBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006013; P:mannose metabolic process; IDA:PomBase.
11Q9SEK2    497   HXK1_TOBAC Hexokinase-1 OS=Nicotiana tabacum ...4647e-83     271     36     52GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
12Q04409    500   EMI2_YEAST Putative glucokinase-2 OS=Saccharo...4773e-81     267     37     52GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
13Q9NFT7    486   HXK2_DROME Hexokinase type 2 OS=Drosophila me...4645e-81     266     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; NAS:UniProtKB.
GO:0006096; P:glycolysis; NAS:UniProtKB.
14Q42525    496   HXK1_ARATH Hexokinase-1 OS=Arabidopsis thalia...4603e-80     264     36     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009536; C:plastid; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IDA:TAIR.
GO:0010255; P:glucose mediated signaling pathway; IMP:TAIR.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0012501; P:programmed cell death; IMP:TAIR.
15Q9SEK3    498   HXK1_SPIOL Hexokinase-1 OS=Spinacia oleracea ...4615e-80     264     36     53GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
16Q9SQ76    496   HXK2_SOLTU Hexokinase-2 OS=Solanum tuberosum ...4612e-79     262     36     51GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
17Q2TB90    917   HKDC1_HUMAN Putative hexokinase HKDC1 OS=Homo...4712e-59     214     30     54GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
18P05708    918   HXK1_RAT Hexokinase-1 OS=Rattus norvegicus (R...4673e-60     217     29     54GO:0005901; C:caveola; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0016887; F:ATPase activity; IC:RGD.::GO:0004340; F:glucokinase activity; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004672; F:protein kinase activity; IDA:RGD.
GO:0006096; P:glycolysis; IDA:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0010359; P:regulation of anion channel activity; IDA:RGD.
19P93834    502   HXK2_ARATH Hexokinase-2 OS=Arabidopsis thalia...4642e-78     259     36     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009747; P:hexokinase-dependent signaling; IMP:TAIR.::GO:0012501; P:programmed cell death; IMP:TAIR.
20Q8LQ68    506   HXK6_ORYSJ Hexokinase-6 OS=Oryza sativa subsp...4633e-78     259     35     52GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
21A2PYL6    917   HXK2_HORSE Hexokinase-2 OS=Equus caballus (Ho...4704e-67     237     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
22A2PYL7    917   HXK2_EQUZE Hexokinase-2 OS=Equus zebra (Mount...4704e-67     237     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
23A2PYL8    917   HXK2_EQUGR Hexokinase-2 OS=Equus grevyi (Grev...4704e-67     237     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
24Q2KNB7    502   HXK9_ORYSJ Hexokinase-9 OS=Oryza sativa subsp...4597e-78     258     35     51GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
25P19367    917   HXK1_HUMAN Hexokinase-1 OS=Homo sapiens (Huma...4671e-61     221     30     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc.
GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; TAS:ProtInc.::GO:0055085; P:transmembrane transport; TAS:Reactome.
26P17710    974   HXK1_MOUSE Hexokinase-1 OS=Mus musculus (Mous...4931e-60     218     29     52GO:0005829; C:cytosol; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI.
GO:0006096; P:glycolysis; TAS:MGI.
27Q6CUZ3    481   HXKG_KLULA Glucokinase-1 OS=1267 / NRRL Y-114...4871e-76     254     37     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004340; F:glucokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
28Q1W674    917   HXK2_PIG Hexokinase-2 OS=Sus scrofa (Pig). GN...4704e-68     239     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
29Q91W97    915   HKDC1_MOUSE Putative hexokinase HKDC1 OS=Mus ...4714e-65     231     30     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
30P27595    918   HXK1_BOVIN Hexokinase-1 OS=Bos taurus (Bovine...4674e-52     193     28     52GO:0005829; C:cytosol; ISS:AgBase.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; ISS:AgBase.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
31O08528    917   HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous...4705e-68     239     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI.
records
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