Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL253W
Length:
486
Number of sequences:
5887
Description:
YGL253W HXK2 SGDID:S000003222, Chr VII from 23935-25395, Genome Release 64-1-1, Verified ORF, "Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31O08528    917   HXK2_MOUSE Hexokinase-2 OS=Mus musculus (Mous...4705e-68     239     33     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IDA:MGI.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0046324; P:regulation of glucose import; IMP:MGI.
32P27881    917   HXK2_RAT Hexokinase-2 OS=Rattus norvegicus (R...4641e-69     244     33     54GO:0005741; C:mitochondrial outer membrane; TAS:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005536; F:glucose binding; IDA:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0007595; P:lactation; IEP:RGD.
33Q5RC71    917   HXK1_PONAB Hexokinase-1 OS=Pongo abelii (Suma...4679e-61     218     30     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
34Q5W676    507   HXK5_ORYSJ Hexokinase-5 OS=Oryza sativa subsp...4784e-75     251     35     53GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
35P52789    917   HXK2_HUMAN Hexokinase-2 OS=Homo sapiens (Huma...4707e-69     241     33     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; TAS:ProtInc.
GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0055085; P:transmembrane transport; TAS:Reactome.
36P52790    923   HXK3_HUMAN Hexokinase-3 OS=Homo sapiens (Huma...4785e-42     164     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; NAS:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004396; F:hexokinase activity; NAS:UniProtKB.
GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; NAS:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome.
37Q2KNB9    494   HXK2_ORYSJ Hexokinase-2 OS=Oryza sativa subsp...4512e-73     246     36     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
38Q9LPS1    498   HXK3_ARATH Hexokinase-3 OS=Arabidopsis thalia...4742e-73     246     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0009536; C:plastid; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
39Q1WM16    463   HXK7_ORYSJ Hexokinase-7 OS=Oryza sativa subsp...4366e-73     244     36     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
40Q9FZG4    493   HXKL1_ARATH Hexokinase-like 1 protein OS=Arab...4591e-72     244     33     51GO:0009507; C:chloroplast; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008865; F:fructokinase activity; IDA:TAIR.::GO:0004340; F:glucokinase activity; IDA:TAIR.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
41Q6Z398    509   HXK4_ORYSJ Hexokinase-4, chloroplastic OS=Ory...4453e-72     243     35     52GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
42Q3TRM8    922   HXK3_MOUSE Hexokinase-3 OS=Mus musculus (Mous...4808e-43     166     27     46GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
43P52792    465   HXK4_MOUSE Glucokinase OS=Mus musculus (Mouse...4699e-72     241     31     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.
GO:0070509; P:calcium ion import; IMP:UniProtKB.::GO:0001678; P:cellular glucose homeostasis; IMP:MGI.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006739; P:NADP metabolic process; IMP:MGI.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0043266; P:regulation of potassium ion transport; IMP:MGI.
44P27926    924   HXK3_RAT Hexokinase-3 OS=Rattus norvegicus (R...4835e-51     190     29     48GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:RGD.::GO:0004396; F:hexokinase activity; IDA:RGD.::GO:0042562; F:hormone binding; IPI:RGD.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
45P35557    465   HXK4_HUMAN Glucokinase OS=Homo sapiens (Human...4664e-71     239     31     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004340; F:glucokinase activity; IDA:UniProtKB.::GO:0005536; F:glucose binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; ISS:BHF-UCL.::GO:0051594; P:detection of glucose; IMP:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0015758; P:glucose transport; TAS:Reactome.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0045721; P:negative regulation of gluconeogenesis; IMP:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0010827; P:regulation of glucose transport; TAS:Reactome.::GO:0006110; P:regulation of glycolysis; NAS:BHF-UCL.::GO:0055085; P:transmembrane transport; TAS:Reactome.
46P17712    465   HXK4_RAT Glucokinase OS=Rattus norvegicus (Ra...4665e-71     239     31     54GO:0044448; C:cell cortex part; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004340; F:glucokinase activity; ISS:UniProtKB.::GO:0005536; F:glucose binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0019903; F:protein phosphatase binding; IPI:RGD.
GO:0001678; P:cellular glucose homeostasis; IMP:RGD.::GO:0042149; P:cellular response to glucose starvation; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0044320; P:cellular response to leptin stimulus; IDA:BHF-UCL.::GO:0051594; P:detection of glucose; ISS:UniProtKB.::GO:0007204; P:elevation of cytosolic calcium ion concentration; IDA:RGD.::GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IDA:RGD.::GO:0005978; P:glycogen biosynthetic process; IDA:RGD.::GO:0006096; P:glycolysis; IDA:RGD.::GO:0032811; P:negative regulation of epinephrine secretion; IMP:RGD.::GO:0045721; P:negative regulation of gluconeogenesis; ISS:UniProtKB.::GO:0045725; P:positive regulation of glycogen biosynthetic process; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; IDA:RGD.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IDA:RGD.::GO:0019932; P:second-messenger-mediated signaling; IDA:RGD.
47Q1WM15    458   HXK8_ORYSJ Hexokinase-8 OS=Oryza sativa subsp...4757e-71     238     36     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
48Q6Q8A5    499   HXK2_TOBAC Hexokinase-2, chloroplastic OS=Nic...4545e-69     234     34     52GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
49Q2KNB4    500   HXK3_ORYSJ Hexokinase-3 OS=Oryza sativa subsp...4627e-69     234     34     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
50Q26609    451   HXK_SCHMA Hexokinase OS=Schistosoma mansoni (...4591e-67     230     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
51O64390    498   HXK1_SOLTU Hexokinase-1 OS=Solanum tuberosum ...4681e-66     228     33     49GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
52Q56XE8    502   HXK4_ARATH Hexokinase-4 OS=Arabidopsis thalia...4693e-66     228     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
53Q8LH82    498   HXK1_ORYSJ Hexokinase-1 OS=Oryza sativa subsp...4208e-58     204     34     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
54Q2KNB5    504   HXK10_ORYSJ Hexokinase-10 OS=Oryza sativa sub...4727e-57     202     32     49GO:0009707; C:chloroplast outer membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
55Q02155    493   HXK_PLAFA Hexokinase OS=Plasmodium falciparum...4878e-51     185     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
56Q969A8    468   HXK_TOXGO Hexokinase OS=Toxoplasma gondii. GN...4841e-48     179     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
57Q9NFT9    465   HXK1_DROME Hexokinase type 1 OS=Drosophila me...4641e-46     173     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
58Q4U3Y2    549   HXK1_ASPFU Hexokinase-1 OS=A1100) (Aspergillu...4561e-41     160     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
59Q9T071    493   HXKL2_ARATH Probable hexokinase-like 2 protei...4614e-32     131     26     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006974; P:response to DNA damage stimulus; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0010224; P:response to UV-B; IEP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.
60O33925    629   SYM_THEMA Methionine--tRNA ligase OS=Thermoto...390.29     37.4     44     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004825; F:methionine-tRNA ligase activity; IEA:EC.::GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
GO:0006431; P:methionyl-tRNA aminoacylation; IEA:InterPro.
61Q06204    433   YL446_YEAST Putative hexokinase YLR446W OS=Sa...2260.92     35.8     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004396; F:hexokinase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 70 31 - 60
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::