Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL251C
Length:
1187
Number of sequences:
5887
Description:
YGL251C HFM1 SGDID:S000003220, Chr VII from 31426-27921,31636-31579, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P51979    1187   HFM1_YEAST ATP-dependent DNA helicase MER3 OS...11870     2456     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003678; F:DNA helicase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0007129; P:synapsis; IMP:SGD.
2A2RUV5    1336   HFM1_XENTR Probable ATP-dependent DNA helicas...244.2     35.4     54     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
3A2PYH4    1435   HFM1_HUMAN Probable ATP-dependent DNA helicas...370.41     38.5     54     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
4Q54G57    2195   HELC1_DICDI Activating signal cointegrator 1 ...6974e-79     291     33     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q9VUV9    2142   U520_DROME Putative U5 small nuclear ribonucl...6426e-64     243     28     50GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007067; P:mitosis; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
6Q55CI8    2237   HELCL_DICDI Activating signal cointegrator 1 ...7167e-57     220     26     49GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:dictyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008380; P:RNA splicing; ISS:dictyBase.
7Q9UT24    2176   BRR2_SCHPO Pre-mRNA-splicing factor brr2 OS=S...7427e-44     178     23     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005682; C:U5 snRNP; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IGI:PomBase.
8O60072    1935   MUG81_SCHPO Putative helicase mug81 OS=Schizo...8121e-70     264     30     49GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.
9Q8N3C0    2202   ASCC3_HUMAN Activating signal cointegrator 1 ...7574e-70     262     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10F1NTD6    2211   ASCC3_CHICK Activating signal cointegrator 1 ...7548e-71     264     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11E9PZJ8    2198   ASCC3_MOUSE Activating signal cointegrator 1 ...7566e-70     261     28     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12E1BNG3    2201   ASCC3_BOVIN Activating signal cointegrator 1 ...7541e-68     258     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13P32639    2163   BRR2_YEAST Pre-mRNA-splicing helicase BRR2 OS...6383e-35     150     25     45GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IMP:SGD.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000388; P:spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); IMP:SGD.
14O75643    2136   U520_HUMAN U5 small nuclear ribonucleoprotein...5682e-68     257     31     53GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005682; C:U5 snRNP; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IDA:HGNC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
15E7F8F4    1534   ASCC3_DANRE Activating signal cointegrator 1 ...5801e-66     251     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16P53327    1967   SLH1_YEAST Antiviral helicase SLH1 OS=Sacchar...5976e-60     230     30     51GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IMP:SGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
17Q9U2G0    2145   U520_CAEEL Putative U5 small nuclear ribonucl...7636e-59     227     25     47GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
18F1LPQ2    2197   ASCC3_RAT Activating signal cointegrator 1 co...5665e-70     262     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19O59025    715   HELS_PYRHO Putative ski2-type helicase OS=NBR...4952e-47     186     31     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
20Q9V0A9    715   HELS_PYRAB Putative ski2-type helicase OS=Pyr...4883e-46     182     32     50
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:HAMAP.
GO:0006281; P:DNA repair; IEA:InterPro.
21Q97AI2    674   HELS_THEVO Putative ski2-type helicase OS=154...3938e-43     171     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
22O73946    720   HELS_PYRFU Putative ski2-type helicase OS=Pyr...5199e-43     171     30     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
23Q9HJX7    674   HELS_THEAC Putative ski2-type helicase OS=NBR...3951e-42     171     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
24A6UN73    751   HELS_METVS Putative ski2-type helicase OS=Met...4691e-42     171     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
25Q5UYM9    799   HELS_HALMA Putative ski2-type helicase OS=B-1...5439e-40     162     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
26Q9HMV6    783   HELS_HALSA Putative ski2-type helicase OS=(Ha...4263e-39     161     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
27B0R7Q2    783   HELS_HALS3 Putative ski2-type helicase OS=Hal...4263e-39     161     29     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
28Q8PZR7    730   HELS_METMA Putative ski2-type helicase OS=JCM...5341e-38     159     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
29Q3IU46    747   HELS_NATPD Putative ski2-type helicase OS=Nat...5492e-38     158     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
30Q465R3    729   HELS_METBF Putative ski2-type helicase OS=Met...5866e-38     156     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
31Q12WZ6    760   HELS_METBU Putative ski2-type helicase OS=Met...5337e-38     156     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
records
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