Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL244W
Length:
558
Number of sequences:
5887
Description:
YGL244W RTF1 SGDID:S000003213, Chr VII from 41498-43174, Genome Release 64-1-1, Verified ORF, "Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53064    558   RTF1_YEAST RNA polymerase-associated protein ...5580     1140     100     100GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0035327; C:transcriptionally active chromatin; IDA:SGD.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:SGD.::GO:0001076; F:RNA polymerase II transcription factor binding transcription factor activity; IPI:SGD.
GO:0070911; P:global genome nucleotide-excision repair; IMP:SGD.::GO:0016570; P:histone modification; IEA:InterPro.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001165; P:positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues; IMP:SGD.::GO:2001209; P:positive regulation of transcription elongation from RNA polymerase I promoter; IDA:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0034402; P:recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:2001173; P:regulation of histone H2B conserved C-terminal lysine ubiquitination; IDA:SGD.::GO:0051569; P:regulation of histone H3-K4 methylation; IMP:SGD.::GO:2001160; P:regulation of histone H3-K79 methylation; IMP:SGD.::GO:0031126; P:snoRNA 3'-end processing; IMP:SGD.::GO:0001015; P:snoRNA transcription from an RNA polymerase II promoter; IMP:SGD.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
2O94667    560   RTF1_SCHPO RNA polymerase-associated protein ...4848e-41     159     30     50GO:0016593; C:Cdc73/Paf1 complex; ISS:PomBase.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0016571; P:histone methylation; ISS:PomBase.::GO:0016574; P:histone ubiquitination; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
3Q5RAD5    665   RTF1_PONAB RNA polymerase-associated protein ...2563e-19     95.5     23     49GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.
GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0016570; P:histone modification; IEA:InterPro.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
4Q92541    710   RTF1_HUMAN RNA polymerase-associated protein ...2563e-19     95.1     23     50GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; ISS:UniProtKB.::GO:0016570; P:histone modification; IEA:InterPro.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
5A2AQ19    715   RTF1_MOUSE RNA polymerase-associated protein ...2564e-19     94.7     23     50GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; IDA:MGI.
GO:0003697; F:single-stranded DNA binding; ISS:UniProtKB.
GO:0001711; P:endodermal cell fate commitment; IMP:UniProtKB.::GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0019827; P:stem cell maintenance; IMP:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
6Q9W261    775   RTF1_DROME RNA polymerase-associated protein ...2683e-16     85.9     26     49GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0035327; C:transcriptionally active chromatin; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0042800; F:histone methyltransferase activity (H3-K4 specific); IMP:UniProtKB.
GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IGI:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:FlyBase.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
7Q4G0S7    254   CC152_HUMAN Coiled-coil domain-containing pro...724.7     33.1     29     58
8Q5UQZ8    101   YR900_MIMIV Uncharacterized protein R900 OS=A...595.2     31.6     29     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
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