Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL213C
Length:
397
Number of sequences:
5887
Description:
YGL213C SKI8 SGDID:S000003181, Chr VII from 91247-90054, Genome Release 64-1-1, reverse complement, Verified ORF, "Ski complex component and WD-repeat protein, mediates 3'-5' RNA degradation by the cytoplasmic exosome; also required for meiotic double-strand break recombination; null mutants have superkiller phenotype"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q02793    397   SKI8_YEAST Antiviral protein SKI8 OS=Saccharo...3970     819     100     100GO:0000228; C:nuclear chromosome; IDA:SGD.::GO:0055087; C:Ski complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IMP:SGD.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0065004; P:protein-DNA complex assembly; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
2Q09150    302   REC14_SCHPO Meiotic recombination protein rec...3950.0000000000001     74.3     24     39GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0055087; C:Ski complex; ISS:PomBase.
GO:0006402; P:mRNA catabolic process; ISS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
3Q6P5M2    305   WDR61_DANRE WD repeat-containing protein 61 O...1340.2     37     25     45GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
4Q26544    301   WSL17_SCHMA WD repeat-containing protein SL1-...1430.00000006     57.4     31     43
5Q6PAX7    607   WDR1B_XENLA WD repeat-containing protein 1-B ...1680.0000002     56.6     29     48GO:0005884; C:actin filament; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.
GO:0030043; P:actin filament fragmentation; ISS:UniProtKB.
6Q8W1K8    370   MUT11_CHLRE Protein Mut11 OS=Chlamydomonas re...1617.7     32.3     24     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
7Q9W7F2    607   WDR1A_XENLA WD repeat-containing protein 1-A ...1120.0000008     54.7     32     50GO:0005884; C:actin filament; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.
GO:0030043; P:actin filament fragmentation; IDA:UniProtKB.
8P49695    742   PKWA_THECU Probable serine/threonine-protein ...1380.007     42.4     22     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
9Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1340.11     38.5     25     43
10Q6DIF4    607   WDR1_XENTR WD repeat-containing protein 1 OS=...1090.000008     51.6     30     50GO:0005884; C:actin filament; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.
GO:0030043; P:actin filament fragmentation; ISS:UniProtKB.
11Q4V7A0    305   WDR61_RAT WD repeat-containing protein 61 OS=...1540.000008     50.8     29     47GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
12Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...1540.000008     50.8     29     47GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
13Q32LN7    305   WDR61_BOVIN WD repeat-containing protein 61 O...1540.00001     50.4     29     47GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
14Q9GZS3    305   WDR61_HUMAN WD repeat-containing protein 61 O...1540.00001     50.4     29     47GO:0016593; C:Cdc73/Paf1 complex; IDA:UniProtKB.::GO:0055087; C:Ski complex; IDA:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0080182; P:histone H3-K4 trimethylation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IDA:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; IMP:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; IMP:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
15Q6PBD6    305   WDR61_XENTR WD repeat-containing protein 61 O...1540.00005     48.5     28     45GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
16O54927    421   WSB1_MOUSE WD repeat and SOCS box-containing ...1416     32.7     24     45
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
17Q9Y6I7    421   WSB1_HUMAN WD repeat and SOCS box-containing ...1408     32.3     24     40GO:0005622; C:intracellular; IDA:LIFEdb.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
18Q5ZJH5    305   WDR61_CHICK WD repeat-containing protein 61 O...1540.00007     47.8     28     45GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
19Q7T2F6    423   WSB1_DANRE WD repeat and SOCS box-containing ...909.9     32     28     40
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
20Q9QXE7    527   TBL1X_MOUSE F-box-like/WD repeat-containing p...3380.0001     47.8     23     36GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0045444; P:fat cell differentiation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0043627; P:response to estrogen stimulus; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q6P1V3    422   WSB1_XENTR WD repeat and SOCS box-containing ...919.9     32     30     48
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
22Q9VU65    391   POC1_DROME POC1 centriolar protein homolog OS...2640.0001     47.4     24     39
GO:0051297; P:centrosome organization; IMP:FlyBase.
23Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...1058.2     32.7     26     47
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
24Q0P593    415   WDR69_BOVIN Outer row dynein assembly protein...484.8     33.1     31     46GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
25O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...3380.0004     46.2     22     36GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26Q8N136    415   WDR69_HUMAN Outer row dynein assembly protein...485.8     32.7     31     46GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
27Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...3380.0004     46.2     22     36GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28Q8BHJ5    514   TBL1R_MOUSE F-box-like/WD repeat-containing p...3360.0004     46.2     22     37
GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q39836    325   GBLP_SOYBN Guanine nucleotide-binding protein...2970.0005     45.4     23     40
30Q498M4    334   WDR5_RAT WD repeat-containing protein 5 OS=Ra...1360.072     38.5     24     49GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P61965    334   WDR5_MOUSE WD repeat-containing protein 5 OS=...1360.072     38.5     24     49GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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