Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL190C
Length:
526
Number of sequences:
5887
Description:
YGL190C CDC55 SGDID:S000003158, Chr VII from 147389-145809, Genome Release 64-1-1, reverse complement, Verified ORF, "Non-essential regulatory subunit B of protein phosphatase 2A (PP2A); involved in regulation of mitotic exit; required for correct nuclear division and chromosome segregation in meiosis; maintains sequestration of the phosphatase Cdc14p in nucleolus during early meiosis, which is essential for meiosis I spindle assembly; limits formation of PP2A-Rts1p holocomplexes to ensure timely dissolution of sister chromosome cohesion; found in nucleus, bud neck and bud of most cells"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q00362    526   2ABA_YEAST Protein phosphatase PP2A regulator...5260     1088     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008601; F:protein phosphatase type 2A regulator activity; IPI:SGD.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0001100; P:negative regulation of exit from mitosis; IMP:SGD.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0006470; P:protein dephosphorylation; TAS:SGD.::GO:0007165; P:signal transduction; IEA:InterPro.
2P53031    508   2ABA_CANTR Protein phosphatase PP2A regulator...5280     635     62     74GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
3Q12702    463   2ABA_SCHPO Protein phosphatase PP2A regulator...5409e-180     521     52     65GO:0005829; C:cytosol; IDA:PomBase.::GO:0000159; C:protein phosphatase type 2A complex; IC:PomBase.::GO:0005819; C:spindle; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:PomBase.
GO:0034260; P:negative regulation of GTPase activity; IGI:PomBase.::GO:0031030; P:negative regulation of septation initiation signaling cascade; IGI:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.::GO:2000769; P:regulation of establishment or maintenance of cell polarity regulating cell shape; IMP:PomBase.::GO:0032995; P:regulation of fungal-type cell wall biogenesis; IMP:PomBase.::GO:0034047; P:regulation of protein phosphatase type 2A activity; IC:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
4Q39247    501   2ABB_ARATH Serine/threonine protein phosphata...5583e-151     449     46     60GO:0005829; C:cytosol; IDA:TAIR.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
5P56932    453   2ABD_RAT Serine/threonine-protein phosphatase...320.000009     52     69     81GO:0005829; C:cytosol; TAS:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008195; F:phosphatidate phosphatase activity; TAS:Reactome.::GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
6Q925E7    453   2ABD_MOUSE Serine/threonine-protein phosphata...320.000009     52     69     81GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
7Q66LE6    453   2ABD_HUMAN Serine/threonine-protein phosphata...320.000007     52     69     81GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
8Q6NY64    447   2ABD_DANRE Serine/threonine-protein phosphata...320.0000006     55.5     72     84GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
9Q5ZIY5    451   2ABD_CHICK Serine/threonine-protein phosphata...320.000002     53.5     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
10Q5R4A2    443   2ABB_PONAB Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
11Q6ZWR4    443   2ABB_MOUSE Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
12Q4R8L3    443   2ABB_MACFA Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
13Q00005    443   2ABB_HUMAN Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
14Q5E9Q7    443   2ABB_BOVIN Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
15Q0D2F4    443   2ABB_XENTR Serine/threonine-protein phosphata...320.000002     54.3     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
16Q6DIY3    447   2ABD_XENTR Serine/threonine-protein phosphata...320.000007     52     69     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
17P36877    443   2ABB_RAT Serine/threonine-protein phosphatase...320.000002     53.9     72     81GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007420; P:brain development; IEP:RGD.::GO:0033554; P:cellular response to stress; IEP:RGD.::GO:0043653; P:mitochondrial fragmentation involved in apoptosis; IMP:RGD.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0043525; P:positive regulation of neuron apoptotic process; IDA:RGD.::GO:0006626; P:protein targeting to mitochondrion; IMP:RGD.::GO:0034047; P:regulation of protein phosphatase type 2A activity; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007286; P:spermatid development; IEP:RGD.
18A1L3L9    468   2ABB_XENLA Serine/threonine-protein phosphata...320.000001     54.3     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
19P36872    499   2ABA_DROME Protein phosphatase PP2A 55 kDa re...550.000001     55.1     49     67GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; IMP:FlyBase.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007447; P:imaginal disc pattern formation; IMP:UniProtKB.::GO:0045201; P:maintenance of neuroblast polarity; IMP:FlyBase.::GO:0000090; P:mitotic anaphase; IMP:FlyBase.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:FlyBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:UniProtKB.::GO:0007423; P:sensory organ development; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IMP:FlyBase.
20B6VA23    443   2ABB_CARAU Serine/threonine-protein phosphata...320.000002     54.3     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
21P63150    447   2ABA_RABIT Serine/threonine-protein phosphata...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; ISS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
22Q6P1F6    447   2ABA_MOUSE Serine/threonine-protein phosphata...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0043278; P:response to morphine; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
23Q4R7Z4    447   2ABA_MACFA Serine/threonine-protein phosphata...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
24P63151    447   2ABA_HUMAN Serine/threonine-protein phosphata...320.000003     53.5     69     81GO:0005829; C:cytosol; TAS:Reactome.::GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008601; F:protein phosphatase type 2A regulator activity; TAS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0010467; P:gene expression; TAS:Reactome.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
25P36876    447   2ABA_RAT Serine/threonine-protein phosphatase...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
26Q7ZX64    447   2ABD_XENLA Serine/threonine-protein phosphata...320.000007     52     69     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008601; F:protein phosphatase type 2A regulator activity; IMP:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; IMP:UniProtKB.::GO:0007067; P:mitosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
27Q5Z8Z7    581   2ABA_ORYSJ Serine/threonine protein phosphata...5587e-143     431     43     59GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
28Q29090    426   2ABA_PIG Serine/threonine-protein phosphatase...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
29Q00006    413   2ABB_RABIT Serine/threonine-protein phosphata...320.000002     53.9     72     81GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
30Q38821    513   2ABA_ARATH Serine/threonine protein phosphata...5582e-140     422     43     57GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro.
GO:0008601; F:protein phosphatase type 2A regulator activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
31Q9Y2T4    447   2ABG_HUMAN Serine/threonine-protein phosphata...320.000003     53.5     69     81GO:0000159; C:protein phosphatase type 2A complex; NAS:UniProtKB.
GO:0008601; F:protein phosphatase type 2A regulator activity; NAS:UniProtKB.
GO:0007165; P:signal transduction; NAS:UniProtKB.
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