Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL185C
Length:
379
Number of sequences:
5887
Description:
YGL185C YGL185C SGDID:S000003153, Chr VII from 154306-153167, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein with sequence similarity to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q59516    314   DHGY_METEA Glycerate dehydrogenase OS=Methylo...1750.000000006     60.5     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
152Q91Z53    328   GRHPR_MOUSE Glyoxylate reductase/hydroxypyruv...1730.000000008     60.1     28     46
GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
153A1JRR3    313   GHRA_YERE8 Glyoxylate/hydroxypyruvate reducta...1450.000000009     60.1     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
154P56545    445   CTBP2_HUMAN C-terminal-binding protein 2 OS=H...2810.00000001     60.5     25     39GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
155A9MH27    312   GHRA_SALAR Glyoxylate/hydroxypyruvate reducta...2160.00000001     59.7     25     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
156A8GD46    313   GHRA_SERP5 Glyoxylate/hydroxypyruvate reducta...1450.00000001     59.7     32     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
157Q9EQH5    445   CTBP2_RAT C-terminal-binding protein 2 OS=Rat...2810.00000001     59.7     25     39GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
158P56546    445   CTBP2_MOUSE C-terminal-binding protein 2 OS=M...2810.00000001     59.7     25     39GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB.
159Q13363    440   CTBP1_HUMAN C-terminal-binding protein 1 OS=H...2820.00000003     58.9     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
160Q9Z2F5    430   CTBP1_RAT C-terminal-binding protein 1 OS=Rat...2820.00000003     58.9     26     39GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD.
GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB.
161Q4L8G4    318   Y752_STAHJ Putative 2-hydroxyacid dehydrogena...1090.00000003     58.5     30     52
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
162O88712    441   CTBP1_MOUSE C-terminal-binding protein 1 OS=M...2820.00000003     58.5     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB.
163P40054    469   SERA_YEAST D-3-phosphoglycerate dehydrogenase...3570.00000004     58.5     22     41GO:0005737; C:cytoplasm; IDA:SGD.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
164Q9YHU0    440   CTBP1_XENLA C-terminal-binding protein 1 OS=X...2820.00000004     58.2     26     39GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
165A6VXM3    380   PDXB_MARMS Erythronate-4-phosphate dehydrogen...1520.00000005     58.2     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
166Q9P7Q1    332   DDH2_SCHPO 2-hydroxyacid dehydrogenase homolo...1750.00000006     57.4     26     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
167P40510    469   SER33_YEAST D-3-phosphoglycerate dehydrogenas...1650.00000006     57.8     25     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004617; F:phosphoglycerate dehydrogenase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
168B7LTA2    312   GHRA_ESCF3 Glyoxylate/hydroxypyruvate reducta...2200.00000008     57     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
169Q9P7P8    332   DDH1_SCHPO 2-hydroxyacid dehydrogenase homolo...1380.00000009     57     28     48GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
170Q5WXZ0    350   PDXB_LEGPL Erythronate-4-phosphate dehydrogen...1480.00000009     57     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
171O83080    331   LDHD_TREPA D-lactate dehydrogenase OS=Trepone...2970.0000001     56.6     24     39
GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
172Q49ZM5    318   Y606_STAS1 Putative 2-hydroxyacid dehydrogena...790.0000001     56.6     38     57
GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
173Q1QXV7    383   PDXB_CHRSD Erythronate-4-phosphate dehydrogen...1690.0000001     56.6     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
174P0C1E9    304   YPRB2_CORML Uncharacterized protein in proB 3...1760.0000001     56.2     28     44
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
175Q9SXP2    376   FDH1_ORYSJ Formate dehydrogenase 1, mitochond...1520.0000002     56.2     26     49GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
176Q5ZX15    350   PDXB_LEGPH Erythronate-4-phosphate dehydrogen...1480.0000002     56.2     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
177Q5X6I6    350   PDXB_LEGPA Erythronate-4-phosphate dehydrogen...1480.0000002     56.2     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0033711; F:4-phosphoerythronate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0008615; P:pyridoxine biosynthetic process; IEA:UniProtKB-KW.
178P13443    382   DHGY_CUCSA Glycerate dehydrogenase OS=Cucumis...2110.0000002     56.2     25     42GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0008465; F:glycerate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009854; P:oxidative photosynthetic carbon pathway; IEA:UniProtKB-KW.
179O14075    334   YEAA_SCHPO Putative 2-hydroxyacid dehydrogena...910.0000002     55.8     31     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0047964; F:glyoxylate reductase activity; ISS:PomBase.::GO:0051287; F:NAD binding; IEA:InterPro.
GO:0009436; P:glyoxylate catabolic process; ISS:PomBase.::GO:0006111; P:regulation of gluconeogenesis; IC:PomBase.
180P0C1E8    304   Y2355_CORGL Uncharacterized protein Cgl2355/c...1760.0000003     55.1     27     44
GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
181P33160    401   FDH_PSESR Formate dehydrogenase OS=Pseudomona...1470.0000004     55.1     29     44
GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
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