| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53101 | 465 | STR3_YEAST Cystathionine beta-lyase OS=Saccha... | 465 | 0 | 961 | 100 | 100 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:SGD. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IMP:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0071266; P:'de novo' L-methionine biosynthetic process; IEA:InterPro.::GO:0019346; P:transsulfuration; IMP:SGD. | 2 | O94350 | 390 | CBL_SCHPO Cystathionine beta-lyase OS=Schizos... | 407 | 3e-103 | 320 | 45 | 64 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; ISS:PomBase. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; ISS:PomBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IC:PomBase. | 3 | P53780 | 464 | METC_ARATH Cystathionine beta-lyase, chloropl... | 395 | 6e-79 | 259 | 40 | 58 | GO:0009570; C:chloroplast stroma; IDA:TAIR. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IMP:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; TAS:TAIR. | 4 | A2RM21 | 380 | METC_LACLM Cystathionine beta-lyase OS=Lactoc... | 400 | 1e-65 | 222 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 5 | P0A4K2 | 380 | METC_LACLA Cystathionine beta-lyase OS=lactis... | 400 | 1e-65 | 222 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 6 | O05394 | 379 | MCCB_BACSU Cystathionine gamma-lyase OS=Bacil... | 399 | 3e-65 | 221 | 35 | 56 | | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0047982; F:homocysteine desulfhydrase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 7 | Q55DV9 | 387 | CGL_DICDI Cystathionine gamma-lyase OS=Dictyo... | 402 | 4e-62 | 213 | 37 | 52 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; ISS:dictyBase.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW. | 8 | P0C2T9 | 380 | METC_LACLC Cystathionine beta-lyase OS=Lactoc... | 400 | 6e-61 | 209 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 9 | P55216 | 392 | CGL2_CAEEL Putative cystathionine gamma-lyase... | 388 | 4e-60 | 207 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IEA:EC.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. | 10 | O31632 | 390 | METC_BACSU Cystathionine beta-lyase metC OS=B... | 412 | 2e-58 | 202 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 11 | P56069 | 380 | METB_HELPY Cystathionine gamma-synthase OS=py... | 402 | 4e-58 | 202 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 12 | P00935 | 386 | METB_ECOLI Cystathionine gamma-synthase OS=Es... | 399 | 7e-58 | 201 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IDA:EcoCyc.::GO:0042802; F:identical protein binding; IPI:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IMP:EcoCyc. | 13 | Q1M0P5 | 380 | METB_HELPX Cystathionine gamma-synthase OS=He... | 402 | 3e-57 | 199 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 14 | Q83A83 | 387 | METC_COXBU Cystathionine beta-lyase OS=Coxiel... | 403 | 7e-57 | 199 | 33 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004121; F:cystathionine beta-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 15 | Q8VCN5 | 398 | CGL_MOUSE Cystathionine gamma-lyase OS=Mus mu... | 409 | 5e-54 | 191 | 34 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0044524; P:protein sulfhydration; IDA:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 16 | Q9ZMW7 | 380 | METB_HELPJ Cystathionine gamma-synthase OS=He... | 397 | 7e-54 | 190 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 17 | Q19QT7 | 405 | CGL_PIG Cystathionine gamma-lyase OS=Sus scro... | 409 | 2e-52 | 187 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 18 | Q60HG7 | 405 | CGL_MACFA Cystathionine gamma-lyase OS=Macaca... | 409 | 3e-52 | 187 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 19 | P18757 | 398 | CGL_RAT Cystathionine gamma-lyase OS=Rattus n... | 409 | 4e-52 | 186 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004121; F:cystathionine beta-lyase activity; IDA:RGD.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0006749; P:glutathione metabolic process; IMP:RGD.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB.::GO:0019346; P:transsulfuration; TAS:RGD. | 20 | P31373 | 394 | CYS3_YEAST Cystathionine gamma-lyase OS=Sacch... | 410 | 4e-52 | 186 | 32 | 49 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IDA:SGD.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:SGD.::GO:0019346; P:transsulfuration; IMP:SGD. | 21 | P44502 | 369 | METB_HAEIN Cystathionine gamma-synthase OS=Ha... | 403 | 1e-51 | 184 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 22 | P46807 | 388 | METB_MYCLE Cystathionine gamma-synthase OS=My... | 408 | 4e-51 | 183 | 33 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 23 | Q58DW2 | 405 | CGL_BOVIN Cystathionine gamma-lyase OS=Bos ta... | 391 | 3e-49 | 179 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; ISS:UniProtKB.::GO:0080146; F:L-cysteine desulfhydrase activity; IEA:EC.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB. | | | | | | | | | | GO:0006916; P:anti-apoptosis; ISS:UniProtKB.::GO:0019344; P:cysteine biosynthetic process; ISS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0044524; P:protein sulfhydration; ISS:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; ISS:UniProtKB. | 24 | O31631 | 373 | METI_BACSU Cystathionine gamma-synthase/O-ace... | 404 | 9e-49 | 176 | 32 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 25 | P32929 | 405 | CGL_HUMAN Cystathionine gamma-lyase OS=Homo s... | 394 | 6e-48 | 175 | 34 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004123; F:cystathionine gamma-lyase activity; IDA:UniProtKB.::GO:0047982; F:homocysteine desulfhydrase activity; TAS:Reactome.::GO:0080146; F:L-cysteine desulfhydrase activity; TAS:Reactome.::GO:0044540; F:L-cystine L-cysteine-lyase (deaminating); IMP:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB. | | | | | | | | | | GO:0019344; P:cysteine biosynthetic process; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IPI:UniProtKB.::GO:0044524; P:protein sulfhydration; IMP:UniProtKB.::GO:0018272; P:protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine; IDA:UniProtKB.::GO:0000098; P:sulfur amino acid catabolic process; TAS:Reactome.::GO:0019346; P:transsulfuration; TAS:Reactome. | 26 | P66875 | 388 | METB_MYCTU Cystathionine gamma-synthase OS=My... | 400 | 4e-47 | 172 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0004123; F:cystathionine gamma-lyase activity; IDA:MTBBASE.::GO:0003962; F:cystathionine gamma-synthase activity; IDA:MTBBASE.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:MTBBASE.::GO:0019279; P:L-methionine biosynthetic process from L-homoserine via cystathionine; IMP:MTBBASE. | 27 | P66876 | 388 | METB_MYCBO Cystathionine gamma-synthase OS=My... | 400 | 4e-47 | 172 | 31 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 28 | P13254 | 398 | MEGL_PSEPU Methionine gamma-lyase OS=Pseudomo... | 398 | 1e-46 | 171 | 32 | 49 | | | | | | | | | | | GO:0018826; F:methionine gamma-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro. | 29 | P24601 | 319 | METB_HERAU Probable cystathionine gamma-synth... | 324 | 4e-43 | 159 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 30 | P55217 | 563 | METB_ARATH Cystathionine gamma-synthase, chlo... | 372 | 7e-42 | 160 | 32 | 50 | GO:0009570; C:chloroplast stroma; IDA:TAIR. | | | | | | | | | | GO:0003962; F:cystathionine gamma-synthase activity; IDA:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IMP:TAIR.::GO:0001887; P:selenium compound metabolic process; IDA:TAIR. | 31 | P55218 | 403 | METZ_PSEAE O-succinylhomoserine sulfhydrylase... | 366 | 3e-36 | 142 | 30 | 51 | | | | | | | | | | | GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071268; P:homocysteine biosynthetic process; IEA:InterPro.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. |
