Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL181W
Length:
396
Number of sequences:
5887
Description:
YGL181W GTS1 SGDID:S000003149, Chr VII from 157906-159096, Genome Release 64-1-1, Verified ORF, "Protein involved in Arf3p regulation and in transcription regulation; localizes to the nucleus and to endocytic patches; contains an N-terminal Zn-finger and ArfGAP homology domain, a C-terminal glutamine-rich region, and a UBA (ubiquitin associated) domain; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms, endocytosis; expression oscillates in a pattern similar to metabolic oscillations"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40956    396   GTS1_YEAST Protein GTS1 OS=Saccharomyces cere...3960     821     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0008060; F:ARF GTPase activator activity; IMP:SGD.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007624; P:ultradian rhythm; IMP:SGD.
2O74345    601   UCP3_SCHPO UBA domain-containing protein 3 OS...2279e-27     115     32     48GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; TAS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; ISS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.
3Q5F413    428   SMAP2_CHICK Stromal membrane-associated prote...1480.0000000000002     75.1     34     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
4Q7TN29    428   SMAP2_MOUSE Stromal membrane-associated prote...1240.0000000000002     75.1     38     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
5Q8WU79    429   SMAP2_HUMAN Stromal membrane-associated prote...1240.0000000000002     75.1     38     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
6Q5EA00    429   SMAP2_BOVIN Stromal membrane-associated prote...1240.0000000000004     73.9     38     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
7Q9FL69    483   AGD5_ARATH Probable ADP-ribosylation factor G...1660.0000000000008     73.2     30     49GO:0005829; C:cytosol; IDA:TAIR.::GO:0005768; C:endosome; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032857; P:activation of ARF GTPase activity; IDA:TAIR.::GO:0010227; P:floral organ abscission; IMP:TAIR.
8Q9FVJ3    337   AGD12_ARATH ADP-ribosylation factor GTPase-ac...800.0000000000009     72.4     39     61GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
9Q8LFN9    336   AGD13_ARATH Probable ADP-ribosylation factor ...1290.000000000001     72     33     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009555; P:pollen development; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
10Q8WWN8    1544   ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1250.00000000002     69.3     37     51GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
11Q8IYB5    467   SMAP1_HUMAN Stromal membrane-associated prote...1080.0000000002     65.9     35     50GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
12Q8L7A4    385   AGD11_ARATH Probable ADP-ribosylation factor ...720.0000000002     65.9     43     58
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
13Q91VZ6    440   SMAP1_MOUSE Stromal membrane-associated prote...1080.0000000002     65.9     35     50GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IDA:MGI.::GO:0030276; F:clathrin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045648; P:positive regulation of erythrocyte differentiation; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:MGI.
14O75689    374   ADAP1_HUMAN Arf-GAP with dual PH domain-conta...1250.0000000004     64.7     33     48GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
15Q9UT34    320   YIQ9_SCHPO Uncharacterized protein C824.09c O...1340.0000000004     64.3     36     48GO:0030136; C:clathrin-coated vesicle; ISS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006891; P:intra-Golgi vesicle-mediated transport; ISS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
16Q6ZQK5    770   ACAP2_MOUSE Arf-GAP with coiled-coil, ANK rep...1070.000000002     63.5     36     50
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
17Q5FVC7    770   ACAP2_RAT Arf-GAP with coiled-coil, ANK repea...1070.000000002     63.5     36     50
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
18Q8CGU4    1186   AGAP2_RAT Arf-GAP with GTPase, ANK repeat and...1090.000000002     63.5     32     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030295; F:protein kinase activator activity; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
19Q3UHD9    1186   AGAP2_MOUSE Arf-GAP with GTPase, ANK repeat a...1090.000000002     63.5     32     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0046427; P:positive regulation of JAK-STAT cascade; IMP:MGI.::GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
20Q96P50    834   ACAP3_HUMAN Arf-GAP with coiled-coil, ANK rep...1170.000000002     62.8     32     47
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
21Q5ZK62    781   ACAP2_CHICK Arf-GAP with coiled-coil, ANK rep...1090.000000003     62.8     35     50
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
22Q0WQQ1    232   AGD15_ARATH Probable ADP-ribosylation factor ...1110.000000004     60.1     31     52
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
23Q15057    778   ACAP2_HUMAN Arf-GAP with coiled-coil, ANK rep...1060.000000006     61.6     34     49
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
24Q96P48    1450   ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1230.000000009     61.2     36     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
25Q8R5G7    1538   ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1250.000000009     61.2     34     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
26Q5U464    904   ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe...1370.00000001     60.8     31     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
27Q6IVG4    778   ACAP2_RABIT Arf-GAP with coiled-coil, ANK rep...1060.00000002     60.1     33     49
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
28Q4LDD4    1452   ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1220.00000002     60.1     34     46GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
29Q9NGC3    995   CEG1A_DROME Centaurin-gamma-1A OS=Drosophila ...1070.00000003     59.3     32     48GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
30P38682    493   GLO3_YEAST ADP-ribosylation factor GTPase-act...650.00000005     58.5     43     60GO:0030126; C:COPI vesicle coat; IPI:SGD.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IPI:SGD.
GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048205; P:COPI coating of Golgi vesicle; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD.
31Q8WZ64    1704   ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1250.00000006     58.5     34     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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