Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL179C
Length:
560
Number of sequences:
5887
Description:
YGL179C TOS3 SGDID:S000003147, Chr VII from 165091-163409, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q9WTQ0    707   KPCT_RAT Protein kinase C theta type OS=Rattu...3023e-25     114     29     47GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007568; P:aging; IEP:RGD.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0051491; P:positive regulation of filopodium assembly; IMP:RGD.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0019229; P:regulation of vasoconstriction; IEP:RGD.::GO:0045730; P:respiratory burst; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD.
482O64682    438   PID_ARATH Protein kinase PINOID OS=Arabidopsi...3723e-25     112     27     43GO:0009986; C:cell surface; IDA:TAIR.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0048825; P:cotyledon development; IGI:UniProtKB.::GO:0009958; P:positive gravitropism; IMP:TAIR.::GO:0080167; P:response to karrikin; IEP:TAIR.::GO:0048767; P:root hair elongation; IMP:TAIR.::GO:0048766; P:root hair initiation; IMP:TAIR.
483Q12851    820   M4K2_HUMAN Mitogen-activated protein kinase k...2213e-25     114     35     52GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0006903; P:vesicle targeting; NAS:UniProtKB.
484Q4R8T9    590   CDKL3_MACFA Cyclin-dependent kinase-like 3 OS...3163e-25     113     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
485P41892    1062   CDC7_SCHPO Cell division control protein 7 OS...2904e-25     114     30     49GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IGI:PomBase.
486Q61161    821   M4K2_MOUSE Mitogen-activated protein kinase k...2224e-25     114     35     53GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006903; P:vesicle targeting; IDA:UniProtKB.
487Q9JI10    497   STK3_MOUSE Serine/threonine-protein kinase 3 ...3134e-25     112     31     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI.
488Q6ZI44    365   SAPK6_ORYSJ Serine/threonine-protein kinase S...3574e-25     110     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
489O96013    591   PAK4_HUMAN Serine/threonine-protein kinase PA...3174e-25     113     28     47GO:0005794; C:Golgi apparatus; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; TAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
490Q01314    480   AKT1_BOVIN RAC-alpha serine/threonine-protein...3284e-25     112     27     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
491A2KF29    484   SMKTR_MOUSE Sperm motility kinase Tcr mutant ...2994e-25     112     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
492O55076    298   CDK2_CRIGR Cyclin-dependent kinase 2 OS=Crice...3174e-25     109     28     48GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
493Q8IVW4    592   CDKL3_HUMAN Cyclin-dependent kinase-like 3 OS...3164e-25     113     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
494P53355    1430   DAPK1_HUMAN Death-associated protein kinase 1...2954e-25     114     31     48GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0008624; P:induction of apoptosis by extracellular signals; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000310; P:regulation of N-methyl-D-aspartate selective glutamate receptor activity; ISS:UniProtKB.
495Q04759    706   KPCT_HUMAN Protein kinase C theta type OS=Hom...3024e-25     113     28     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
496Q8BWQ5    790   DCLK3_MOUSE Serine/threonine-protein kinase D...3185e-25     113     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
497Q68UT7    714   HUNK_PANTR Hormonally up-regulated neu tumor-...2785e-25     113     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
498P57058    714   HUNK_HUMAN Hormonally up-regulated neu tumor-...2785e-25     113     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
499Q6PGN3    756   DCLK2_MOUSE Serine/threonine-protein kinase D...3895e-25     113     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
500Q9ST27    907   PHOT2_ORYSJ Phototropin-2 OS=Oryza sativa sub...3255e-25     113     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000155; F:two-component sensor activity; IEA:InterPro.
GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
501P24941    298   CDK2_HUMAN Cyclin-dependent kinase 2 OS=Homo ...3175e-25     109     28     47GO:0015030; C:Cajal body; IDA:UniProtKB.::GO:0005813; C:centrosome; TAS:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071732; P:cellular response to nitric oxide; TAS:UniProtKB.::GO:0051298; P:centrosome duplication; TAS:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0000085; P:G2 phase of mitotic cell cycle; TAS:Reactome.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:ProtInc.::GO:0016572; P:histone phosphorylation; IDA:GOC.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0007126; P:meiosis; TAS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; IEP:BHF-UCL.::GO:0006275; P:regulation of DNA replication; TAS:ProtInc.::GO:0060968; P:regulation of gene silencing; IDA:UniProtKB.::GO:0051439; P:regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0007089; P:traversing start control point of mitotic cell cycle; TAS:ProtInc.
502Q9JI11    487   STK4_MOUSE Serine/threonine-protein kinase 4 ...3325e-25     112     29     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0001569; P:patterning of blood vessels; IGI:MGI.::GO:0060215; P:primitive hemopoiesis; IGI:MGI.
503P31750    480   AKT1_MOUSE RAC-alpha serine/threonine-protein...3285e-25     111     28     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005819; C:spindle; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0042640; P:anagen; IMP:MGI.::GO:0008637; P:apoptotic mitochondrial changes; IDA:MGI.::GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:UniProtKB.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0006006; P:glucose metabolic process; IMP:MGI.::GO:0015758; P:glucose transport; IMP:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0060709; P:glycogen cell development involved in embryonic placenta development; IMP:MGI.::GO:0006954; P:inflammatory response; IDA:MGI.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0060716; P:labyrinthine layer blood vessel development; IMP:MGI.::GO:0001893; P:maternal placenta development; IMP:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0030163; P:protein catabolic process; IDA:MGI.::GO:0016567; P:protein ubiquitination; IDA:MGI.::GO:0010975; P:regulation of neuron projection development; IDA:UniProtKB.::GO:0045884; P:regulation of survival gene product expression; IDA:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0032094; P:response to food; IDA:MGI.::GO:0051146; P:striated muscle cell differentiation; IGI:MGI.
504P87253    1142   KPC1_NEUCR Protein kinase C-like OS=1257 / FG...3436e-25     113     28     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
505Q5E9Y0    298   CDK2_BOVIN Cyclin-dependent kinase 2 OS=Bos t...3176e-25     109     28     48GO:0015030; C:Cajal body; IEA:UniProtKB-SubCell.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:AgBase.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; ISS:AgBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:AgBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:AgBase.::GO:0006813; P:potassium ion transport; ISS:AgBase.
506P47196    480   AKT1_RAT RAC-alpha serine/threonine-protein k...3286e-25     111     28     46GO:0005829; C:cytosol; IDA:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007568; P:aging; IDA:RGD.::GO:0030030; P:cell projection organization; IDA:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:RGD.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045792; P:negative regulation of cell size; IDA:MGI.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:RGD.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0030307; P:positive regulation of cell growth; IDA:RGD.::GO:0045907; P:positive regulation of vasoconstriction; IMP:RGD.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0006412; P:translation; IMP:UniProtKB.
507Q9UBE8    527   NLK_HUMAN Serine/threonine-protein kinase NLK...3126e-25     112     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
508E2QWQ2    527   NLK_CANFA Serine/threonine-protein kinase NLK...3126e-25     112     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
509D3ZSZ3    527   NLK_RAT Serine/threonine-protein kinase NLK O...3126e-25     112     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
510O54949    527   NLK_MOUSE Serine/threonine-protein kinase NLK...3126e-25     112     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
511O54748    491   STK3_RAT Serine/threonine-protein kinase 3 OS...3136e-25     111     31     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
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