Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL179C
Length:
560
Number of sequences:
5887
Description:
YGL179C TOS3 SGDID:S000003147, Chr VII from 165091-163409, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391Q9HBY8    427   SGK2_HUMAN Serine/threonine-protein kinase Sg...3012e-26     115     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015459; F:potassium channel regulator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0017080; F:sodium channel regulator activity; NAS:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032411; P:positive regulation of transporter activity; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:0006979; P:response to oxidative stress; TAS:ProtInc.
392Q12152    901   YP150_YEAST Putative serine/threonine-protein...3142e-26     117     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
393O88764    448   DAPK3_RAT Death-associated protein kinase 3 O...3122e-26     115     28     48GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0030182; P:neuron differentiation; IDA:RGD.::GO:2001241; P:positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
394Q7ZTW4    433   SGK1_DANRE Serine/threonine-protein kinase Sg...3002e-26     115     30     49GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
395P09215    673   KPCD_RAT Protein kinase C delta type OS=Rattu...3302e-26     117     28     45GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0070976; F:TIR domain binding; IPI:BHF-UCL.
GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0015810; P:aspartate transport; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0032963; P:collagen metabolic process; IMP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.
396P49673    337   KAPC_ASCSU cAMP-dependent protein kinase cata...3392e-26     113     26     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC.
397Q9QYZ6    504   SMK2A_MOUSE Sperm motility kinase 2A OS=Mus m...2993e-26     115     29     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
398O61267    476   LOK_DROME Ovarian-specific serine/threonine-p...2903e-26     115     30     48GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0000077; P:DNA damage checkpoint; IDA:FlyBase.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:BHF-UCL.::GO:0007281; P:germ cell development; IEP:UniProtKB.::GO:0035234; P:germ cell programmed cell death; IMP:FlyBase.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IGI:BHF-UCL.
399P08414    469   KCC4_MOUSE Calcium/calmodulin-dependent prote...3043e-26     115     30     47GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:MGI.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0007270; P:neuron-neuron synaptic transmission; IMP:MGI.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:MGI.::GO:0007165; P:signal transduction; IDA:MGI.
400P49071    359   MAPK2_DROME MAP kinase-activated protein kina...3203e-26     114     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IGI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.
401Q9HFF4    1023   PPK1_SCHPO Serine/threonine-protein kinase pp...3533e-26     117     27     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
402P27791    351   KAPCA_RAT cAMP-dependent protein kinase catal...3043e-26     113     28     49GO:0005952; C:cAMP-dependent protein kinase complex; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:RGD.::GO:0034237; F:protein kinase A regulatory subunit binding; IC:RGD.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.
GO:0051447; P:negative regulation of meiotic cell cycle; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043457; P:regulation of cellular respiration; IDA:RGD.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IDA:RGD.
403Q9NJU9    562   CDPK3_PLAF7 Calcium-dependent protein kinase ...2493e-26     116     35     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
404A7MBL8    977   PKN2_DANRE Serine/threonine-protein kinase N2...3063e-26     117     31     49GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
405Q6GLY8    434   SGK1B_XENLA Serine/threonine-protein kinase S...3003e-26     114     29     50GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
406Q6IP06    493   STK3_XENLA Serine/threonine-protein kinase 3 ...3134e-26     115     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
407Q8BWW9    983   PKN2_MOUSE Serine/threonine-protein kinase N2...3324e-26     117     31     46GO:0043296; C:apical junction complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0043297; P:apical junction assembly; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010631; P:epithelial cell migration; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
408Q09136    385   AAPK1_PIG 5'-AMP-activated protein kinase cat...2444e-26     113     31     51GO:0031588; C:AMP-activated protein kinase complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004679; F:AMP-activated protein kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0035174; F:histone serine kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050995; P:negative regulation of lipid catabolic process; ISS:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
409Q55GS4    366   CDK10_DICDI Probable cyclin-dependent kinase ...3164e-26     113     30     47GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051726; P:regulation of cell cycle; ISS:dictyBase.
410P67999    525   KS6B1_RAT Ribosomal protein S6 kinase beta-1 ...3294e-26     115     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0009986; C:cell surface; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004711; F:ribosomal protein S6 kinase activity; IMP:RGD.
GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IEP:RGD.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0032870; P:cellular response to hormone stimulus; IEP:RGD.::GO:0007616; P:long-term memory; IEP:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048633; P:positive regulation of skeletal muscle tissue growth; IMP:RGD.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0046324; P:regulation of glucose import; IMP:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014878; P:response to electrical stimulus involved in regulation of muscle adaptation; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0033762; P:response to glucagon stimulus; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IMP:UniProtKB.::GO:0043201; P:response to leucine; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0034612; P:response to tumor necrosis factor; IMP:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD.::GO:0014732; P:skeletal muscle atrophy; IEP:RGD.::GO:0003009; P:skeletal muscle contraction; IEP:RGD.
411P23443    525   KS6B1_HUMAN Ribosomal protein S6 kinase beta-...3294e-26     115     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; IDA:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0031929; P:TOR signaling cascade; IDA:UniProtKB.
412P67998    525   KS6B1_RABIT Ribosomal protein S6 kinase beta-...3294e-26     115     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.
413O15021    2626   MAST4_HUMAN Microtubule-associated serine/thr...3155e-26     117     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
414O88866    714   HUNK_MOUSE Hormonally up-regulated neu tumor-...2785e-26     116     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
415Q8BSK8    525   KS6B1_MOUSE Ribosomal protein S6 kinase beta-...3295e-26     115     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.
416Q6TJY3    527   KS6B1_BOVIN Ribosomal protein S6 kinase beta-...3295e-26     115     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0071363; P:cellular response to growth factor stimulus; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
417Q6U1I9    432   SGK1_CHICK Serine/threonine-protein kinase Sg...3006e-26     114     29     48GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
418O14299    1401   WIS4_SCHPO MAP kinase kinase kinase wis4 OS=S...2976e-26     116     28     49GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; NAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; NAS:PomBase.
419Q21017    822   KIN29_CAEEL Serine/threonine-protein kinase k...2966e-26     116     29     50GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0043053; P:dauer entry; IMP:WormBase.::GO:0050907; P:detection of chemical stimulus involved in sensory perception; IMP:WormBase.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; TAS:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IGI:WormBase.
420Q10407    1116   MKH1_SCHPO MAP kinase kinase kinase mkh1 OS=S...2296e-26     116     33     52GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033205; P:cell cycle cytokinesis; NAS:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006883; P:cellular sodium ion homeostasis; NAS:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0008360; P:regulation of cell shape; NAS:PomBase.
421Q8BTW9    593   PAK4_MOUSE Serine/threonine-protein kinase PA...3176e-26     115     28     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
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