Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL179C
Length:
560
Number of sequences:
5887
Description:
YGL179C TOS3 SGDID:S000003147, Chr VII from 165091-163409, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q8C0V7    499   SMKW_MOUSE Sperm motility kinase W OS=Mus mus...3047e-32     132     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
152Q8INB9    611   AKT1_DROME RAC serine/threonine-protein kinas...3167e-32     133     32     48GO:0009986; C:cell surface; IDA:FlyBase.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; NAS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; NAS:FlyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IMP:FlyBase.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008362; P:chitin-based embryonic cuticle biosynthetic process; IGI:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0035556; P:intracellular signal transduction; IGI:UniProtKB.::GO:0019915; P:lipid storage; IGI:FlyBase.::GO:0060292; P:long term synaptic depression; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0050773; P:regulation of dendrite development; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.
153Q8LIG4    445   CIPK3_ORYSJ CBL-interacting protein kinase 3 ...2999e-32     130     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
154Q9IA88    798   SIK2_CHICK Serine/threonine-protein kinase SI...2969e-32     134     31     50GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB.
155Q6A1A2    396   PDPK2_HUMAN Putative 3-phosphoinositide-depen...3071e-31     130     34     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
156Q6GPL3    368   AUKBB_XENLA Aurora kinase B-B OS=Xenopus laev...3001e-31     129     29     49GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
157Q54PB4    481   MYLKE_DICDI Probable myosin light chain kinas...3191e-31     130     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
158Q94C40    432   CIPKH_ARATH CBL-interacting serine/threonine-...3011e-31     130     31     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
159Q9Z2A0    559   PDPK1_MOUSE 3-phosphoinositide-dependent prot...3152e-31     131     33     49GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB.
160Q00372    612   SNF1_CANGA Carbon catabolite-derepressing pro...2922e-31     132     30     52GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
161Q5QNM6    511   CIPKD_ORYSJ Putative CBL-interacting protein ...2552e-31     130     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
162O70150    343   KCC1B_RAT Calcium/calmodulin-dependent protei...3012e-31     128     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
163Q9QYK9    343   KCC1B_MOUSE Calcium/calmodulin-dependent prot...3012e-31     128     33     51GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
164Q68Y49    508   CIPKJ_ORYSJ CBL-interacting protein kinase 19...2932e-31     130     28     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
165Q54PK9    908   PDPKB_DICDI 3-phosphoinositide-dependent prot...3682e-31     133     29     45
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
166P52497    620   SNF1_CANAX Carbon catabolite-derepressing pro...2932e-31     132     31     51GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
167B4QK53    769   PLK4_DROSI Serine/threonine-protein kinase PL...3212e-31     132     32     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
168O97143    769   PLK4_DROME Serine/threonine-protein kinase PL...3213e-31     132     32     47GO:0005814; C:centriole; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0046599; P:regulation of centriole replication; IDA:FlyBase.::GO:0007288; P:sperm axoneme assembly; IMP:FlyBase.
169B4IAQ8    769   PLK4_DROSE Serine/threonine-protein kinase PL...3213e-31     132     32     47GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
170P06245    380   KAPB_YEAST cAMP-dependent protein kinase type...3093e-31     128     29     48GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; ISS:SGD.
171O94168    619   SNF1_CANTR Carbon catabolite-derepressing pro...2923e-31     131     30     51GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
172O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...3064e-31     130     34     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
173Q5R7G9    628   NUAK2_PONAB NUAK family SNF1-like kinase 2 OS...3234e-31     131     29     50
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
174Q9H093    628   NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS...3234e-31     131     29     50
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.
175P21137    404   KAPC_CAEEL cAMP-dependent protein kinase cata...3414e-31     128     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:WormBase.
GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.
176Q63450    374   KCC1A_RAT Calcium/calmodulin-dependent protei...3065e-31     127     30     49GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
177Q2LYK3    777   PLK4_DROPS Serine/threonine-protein kinase PL...3005e-31     132     31     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
178B4HBU3    777   PLK4_DROPE Serine/threonine-protein kinase PL...3005e-31     131     31     48GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
179Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...3305e-31     129     30     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
180Q3U214    1321   MAST3_MOUSE Microtubule-associated serine/thr...3545e-31     132     28     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
181Q91YS8    374   KCC1A_MOUSE Calcium/calmodulin-dependent prot...3065e-31     127     30     49GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:MGI.
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