UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL166W

Length:

225

Number of sequences:

5887

Description:

YGL166W CUP2 SGDID:S000003134, Chr VII from 191129-191806, Genome Release 64-1-1, Verified ORF, "Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P15315	225	CUP2_YEAST Transcriptional activator protein ...	225	3e-166	464	100	100	GO:0005634; C:nucleus; IDA:SGD.
									GO:0005507; F:copper ion binding; IDA:SGD.::GO:0001202; F:copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity; IMP:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.
2	P41772	265	AMT1_CANGA Metal-activated transcriptional ac...	251	3e-36	134	34	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3	Q12753	694	HAA1_YEAST Transcriptional activator HAA1 OS=...	115	2e-28	117	48	58	GO:0005634; C:nucleus; IDA:SGD.
									GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.
									GO:0036003; P:positive regulation of transcription from RNA polymerase II promoter in response to stress; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.
4	P45815	411	CRF1_YARLI Copper resistance protein CRF1 OS=...	93	5e-18	85.5	47	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5	Q09728	411	CUF1_SCHPO Metal-binding regulatory protein c...	74	0.0000000002	63.2	47	59	GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005507; F:copper ion binding; IMP:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.
									GO:0006879; P:cellular iron ion homeostasis; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:PomBase.
6	O94588	177	CUF2_SCHPO Copper-binding regulatory protein ...	51	0.0000003	52	39	63	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005507; F:copper ion binding; ISS:PomBase.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:PomBase.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; NAS:PomBase.
									GO:0050801; P:ion homeostasis; ISS:PomBase.
7	P35192	417	MAC1_YEAST Metal-binding activator 1 OS=Sacch...	40	0.0000003	53.5	53	73	GO:0005634; C:nucleus; IDA:SGD.
									GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0001159; F:core promoter proximal region DNA binding; IDA:SGD.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:SGD.
									GO:0006878; P:cellular copper ion homeostasis; IMP:SGD.::GO:0045732; P:positive regulation of protein catabolic process; IMP:SGD.
8	Q92258	597	GRISA_PODAS Protein GRISEA OS=Podospora anser...	86	0.000005	50.1	36	51	GO:0005634; C:nucleus; IC:UniProtKB.
									GO:0005507; F:copper ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0006878; P:cellular copper ion homeostasis; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9	Q6ASC7	695	EFG1_DESPS Elongation factor G 1 OS=Desulfota...	61	3.9	32.3	33	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
10	Q62925	1493	M3K1_RAT Mitogen-activated protein kinase kin...	77	7.2	31.6	30	44	GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008432; F:JUN kinase binding; IPI:RGD.::GO:0004706; F:JUN kinase kinase kinase activity; IDA:RGD.::GO:0004710; F:MAPK/ERK kinase kinase activity; IDA:RGD.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:RGD.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:RGD.::GO:0046625; F:sphingolipid binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0043065; P:positive regulation of apoptotic process; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0050434; P:positive regulation of viral transcription; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0051259; P:protein oligomerization; IDA:RGD.::GO:0000209; P:protein polyubiquitination; IMP:RGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IGI:RGD.::GO:0006970; P:response to osmotic stress; IMP:RGD.

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