UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL154C

Length:

272

Number of sequences:

5887

Description:

YGL154C LYS5 SGDID:S000003122, Chr VII from 216096-215278, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P50113	272	LYS5_YEAST L-aminoadipate-semialdehyde dehydr...	272	0	560	100	100	GO:0005737; C:cytoplasm; TAS:SGD.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IDA:SGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0019878; P:lysine biosynthetic process via aminoadipic acid; TAS:SGD.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.::GO:0018065; P:protein-cofactor linkage; IDA:SGD.]
2	Q6FV34	258	LYS5_CANGA L-aminoadipate-semialdehyde dehydr...	227	1e-39	144	35	56
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
3	Q74Z24	276	LYS5_ASHGO L-aminoadipate-semialdehyde dehydr...	229	6e-20	90.5	31	47
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
4	Q9CQF6	309	ADPPT_MOUSE L-aminoadipate-semialdehyde dehyd...	214	0.0005	44.3	26	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
5	P39144	224	LP14_BACIU 4'-phosphopantetheinyl transferase...	180	0.002	42.4	24	44
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
6	P39135	224	SFP_BACSU 4'-phosphopantetheinyl transferase ...	118	0.002	42	31	51
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
7	Q55185	246	Y495_SYNY3 Putative 4'-phosphopantetheinyl tr...	147	0.005	41.2	27	44
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
8	P40683	237	GSP_ANEMI 4'-phosphopantetheinyl transferase ...	160	0.006	40.8	23	44
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
9	Q6DJH2	302	ADPPT_XENLA L-aminoadipate-semialdehyde dehyd...	115	0.007	40.8	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
10	B2RYJ4	309	ADPPT_RAT L-aminoadipate-semialdehyde dehydro...	214	0.01	40.4	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
11	Q9NRN7	309	ADPPT_HUMAN L-aminoadipate-semialdehyde dehyd...	204	0.019	39.7	25	43	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.]
12	Q5NVE1	309	ADPPT_PONAB L-aminoadipate-semialdehyde dehyd...	204	0.024	39.3	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
13	Q9F4F7	224	FFP_BACIU 4'-phosphopantetheinyl transferase ...	118	0.052	37.7	26	47
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
14	P55810	233	PSF1_BACPU 4'-phosphopantetheinyl transferase...	120	0.063	37.7	28	44
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
15	Q0AF73	125	ACPS_NITEC Holo-[acyl-carrier-protein] syntha...	67	0.17	35	28	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
16	Q28V25	150	ACPS_JANSC Holo-[acyl-carrier-protein] syntha...	47	0.22	35.4	30	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
17	P28021	215	CSK2B_XENLA Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
18	P67874	215	CSK2B_RAT Casein kinase II subunit beta OS=Ra...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:RGD.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; TAS:RGD.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
19	P67873	215	CSK2B_RABIT Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
20	P67872	215	CSK2B_PIG Casein kinase II subunit beta OS=Su...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
21	P67871	215	CSK2B_MOUSE Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
22	P67870	215	CSK2B_HUMAN Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005956; C:protein kinase CK2 complex; NAS:UniProtKB.
									GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0019887; F:protein kinase regulator activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.
									GO:0033211; P:adiponectin-mediated signaling pathway; IDA:BHF-UCL.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0043623; P:cellular protein complex assembly; NAS:BHF-UCL.::GO:0061154; P:endothelial tube morphogenesis; IMP:BHF-UCL.::GO:0043537; P:negative regulation of blood vessel endothelial cell migration; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:BHF-UCL.::GO:0032927; P:positive regulation of activin receptor signaling pathway; IMP:BHF-UCL.::GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL.::GO:0051101; P:regulation of DNA binding; NAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
23	P67869	215	CSK2B_CHICK Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
24	P67868	215	CSK2B_BOVIN Casein kinase II subunit beta OS=...	143	0.89	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
25	Q91398	215	CSK2B_DANRE Casein kinase II subunit beta OS=...	143	0.98	33.9	27	45	GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
									GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
26	P37695	237	HETI_NOSS1 4'-phosphopantetheinyl transferase...	138	1.2	33.9	30	46
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
27	Q4FLS7	128	ACPS_PELUB Holo-[acyl-carrier-protein] syntha...	98	1.7	32.3	21	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]
28	Q66H86	402	OLFL1_RAT Olfactomedin-like protein 1 OS=Ratt...	55	1.9	33.5	35	55	GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
29	Q3A5V3	128	ACPS_PELCD Holo-[acyl-carrier-protein] syntha...	54	4.9	31.2	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0008897; F:holo-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0009059; P:macromolecule biosynthetic process; IEA:InterPro.]

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