Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL141W
Length:
910
Number of sequences:
5887
Description:
YGL141W HUL5 SGDID:S000003109, Chr VII from 238353-241085, Genome Release 64-1-1, Verified ORF, "Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q8CDU6    774   HECD2_MOUSE Probable E3 ubiquitin-protein lig...3635e-30     131     28     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
62P46935    887   NEDD4_MOUSE E3 ubiquitin-protein ligase NEDD4...3786e-30     131     31     48GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI.
GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:MGI.::GO:0019871; F:sodium channel inhibitor activity; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.
GO:0010766; P:negative regulation of sodium ion transport; IDA:MGI.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:UniProtKB.
63Q5U5R9    776   HECD2_HUMAN Probable E3 ubiquitin-protein lig...3639e-30     130     28     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
64Q9VVI3    1007   NEDD4_DROME E3 ubiquitin-protein ligase Nedd-...3649e-30     130     31     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005112; F:Notch binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:FlyBase.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0016199; P:axon midline choice point recognition; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IMP:UniProtKB.::GO:0007528; P:neuromuscular junction development; IMP:FlyBase.::GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.::GO:0002092; P:positive regulation of receptor internalization; IMP:FlyBase.::GO:0051965; P:positive regulation of synapse assembly; IMP:FlyBase.::GO:0031623; P:receptor internalization; IMP:UniProtKB.
65A9JRZ0    765   SMUF2_DANRE E3 ubiquitin-protein ligase SMURF...3611e-29     130     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
66Q9CUN6    731   SMUF1_MOUSE E3 ubiquitin-protein ligase SMURF...3661e-29     129     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0030279; P:negative regulation of ossification; IMP:MGI.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
67Q9HCE7    757   SMUF1_HUMAN E3 ubiquitin-protein ligase SMURF...3663e-29     129     29     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.
GO:0048185; F:activin binding; IPI:BHF-UCL.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:BHF-UCL.::GO:0034394; P:protein localization at cell surface; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0032801; P:receptor catabolic process; IDA:BHF-UCL.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
68P46934    1319   NEDD4_HUMAN E3 ubiquitin-protein ligase NEDD4...3623e-29     129     31     48GO:0016327; C:apicolateral plasma membrane; TAS:BHF-UCL.::GO:0005938; C:cell cortex; IDA:BHF-UCL.::GO:0000785; C:chromatin; IDA:BHF-UCL.::GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0000151; C:ubiquitin ligase complex; ISS:BHF-UCL.
GO:0031698; F:beta-2 adrenergic receptor binding; IDA:UniProtKB.::GO:0050815; F:phosphoserine binding; ISS:BHF-UCL.::GO:0050816; F:phosphothreonine binding; ISS:BHF-UCL.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0070063; F:RNA polymerase binding; IPI:BHF-UCL.::GO:0019871; F:sodium channel inhibitor activity; IDA:BHF-UCL.::GO:0043130; F:ubiquitin binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044111; P:development involved in symbiotic interaction; IMP:UniProtKB.::GO:0042921; P:glucocorticoid receptor signaling pathway; IDA:BHF-UCL.::GO:0010766; P:negative regulation of sodium ion transport; IDA:UniProtKB.::GO:0010768; P:negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; IMP:BHF-UCL.::GO:0030948; P:negative regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IEP:BHF-UCL.::GO:0046824; P:positive regulation of nucleocytoplasmic transport; IDA:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:MGI.::GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006622; P:protein targeting to lysosome; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0032801; P:receptor catabolic process; IDA:UniProtKB.::GO:0031623; P:receptor internalization; IDA:UniProtKB.::GO:0048814; P:regulation of dendrite morphogenesis; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; TAS:BHF-UCL.::GO:0019089; P:transmission of virus; IMP:BHF-UCL.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:BHF-UCL.
69Q2TAS2    751   SMUF2_XENLA E3 ubiquitin-protein ligase SMURF...3616e-29     127     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
70A2A5Z6    748   SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF...3632e-28     126     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
71Q9PUN2    731   SMUF1_XENLA E3 ubiquitin-protein ligase SMURF...3663e-28     125     29     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
72Q9V853    1061   SMUF1_DROME E3 ubiquitin-protein ligase Smurf...3646e-28     125     27     46GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0008101; P:decapentaplegic signaling pathway; IMP:UniProtKB.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:UniProtKB.::GO:0048619; P:embryonic hindgut morphogenesis; IMP:UniProtKB.::GO:0010629; P:negative regulation of gene expression; IDA:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0040008; P:regulation of growth; IMP:FlyBase.
73Q9HAU4    748   SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF...3636e-28     124     30     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046332; F:SMAD binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; NAS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IDA:BHF-UCL.
74Q757T0    839   HUL4_ASHGO Probable E3 ubiquitin-protein liga...3648e-28     124     27     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
75Q9SU29    873   UPL5_ARATH E3 ubiquitin-protein ligase UPL5 O...3561e-25     117     29     46GO:0005737; C:cytoplasm; IDA:TAIR.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0010150; P:leaf senescence; IMP:TAIR.::GO:0042542; P:response to hydrogen peroxide; IEP:UniProtKB.::GO:0009753; P:response to jasmonic acid stimulus; IEP:UniProtKB.
76O15033    823   K0317_HUMAN Protein KIAA0317 OS=Homo sapiens ...3325e-25     115     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
77Q9LYZ7    1502   UPL4_ARATH E3 ubiquitin-protein ligase UPL4 O...4886e-25     115     25     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0006464; P:protein modification process; IEA:InterPro.
78Q8CHG5    823   K0317_MOUSE Protein KIAA0317 OS=Mus musculus ...3311e-24     114     28     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
79O94275    807   MUG30_SCHPO Probable E3 ubiquitin-protein lig...3692e-23     110     27     46GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
80Q10435    1647   YDE1_SCHPO Probable ubiquitin fusion degradat...4414e-23     110     28     45GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:RefGenome.
81Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...3623e-22     106     29     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
82P40985    892   HUL4_YEAST Probable E3 ubiquitin-protein liga...3713e-21     103     27     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
83P33202    1483   UFD4_YEAST Ubiquitin fusion degradation prote...3696e-21     103     28     45GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
84Q14669    1992   TRIPC_HUMAN Probable E3 ubiquitin-protein lig...4788e-21     102     26     40GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0046966; F:thyroid hormone receptor binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
85P51592    2885   HYD_DROME E3 ubiquitin-protein ligase hyd OS=...2738e-21     102     30     50GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048749; P:compound eye development; NAS:FlyBase.::GO:0007455; P:eye-antennal disc morphogenesis; IMP:FlyBase.::GO:0008585; P:female gonad development; IMP:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0007112; P:male meiosis cytokinesis; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; NAS:FlyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0030162; P:regulation of proteolysis; NAS:FlyBase.::GO:0007289; P:spermatid nucleus differentiation; IMP:FlyBase.
86O95071    2799   UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 O...2705e-20     100     29     51GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0034450; F:ubiquitin-ubiquitin ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035413; P:positive regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:BHF-UCL.::GO:0050847; P:progesterone receptor signaling pathway; IDA:HGNC.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; IDA:HGNC.
87Q80TP3    2792   UBR5_MOUSE E3 ubiquitin-protein ligase UBR5 O...2705e-20     100     29     51GO:0005634; C:nucleus; ISS:HGNC.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0050847; P:progesterone receptor signaling pathway; ISS:HGNC.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0006974; P:response to DNA damage stimulus; ISS:HGNC.
88Q62671    2788   UBR5_RAT E3 ubiquitin-protein ligase UBR5 OS=...2708e-20     99.8     28     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
89Q6WWW4    1888   UPL3_ARATH E3 ubiquitin-protein ligase UPL3 O...4917e-19     96.3     23     40GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0006464; P:protein modification process; IEA:InterPro.::GO:0010091; P:trichome branching; IMP:TAIR.
90Q15751    4861   HERC1_HUMAN Probable E3 ubiquitin-protein lig...3323e-18     94.4     25     45GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc.
GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
91Q9UII4    1024   HERC5_HUMAN E3 ISG15--protein ligase HERC5 OS...3623e-17     90.9     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0042296; F:ISG15 ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032020; P:ISG15-protein conjugation; IDA:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0050688; P:regulation of defense response to virus; IDA:UniProtKB.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 109 61 - 90
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::