rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | B3NPW0 | 411 | LIS1_DROER Lissencephaly-1 homolog OS=Drosoph... | 230 | 0.0000000004 | 66.6 | 24 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 62 | B4QHG6 | 411 | LIS1_DROSI Lissencephaly-1 homolog OS=Drosoph... | 45 | 0.001 | 45.8 | 36 | 69 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 63 | B4HSL3 | 411 | LIS1_DROSE Lissencephaly-1 homolog OS=Drosoph... | 45 | 0.001 | 45.8 | 36 | 69 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 64 | Q7KNS3 | 411 | LIS1_DROME Lissencephaly-1 homolog OS=Drosoph... | 45 | 0.001 | 45.8 | 36 | 69 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0005938; C:cell cortex; IDA:FlyBase.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005869; C:dynactin complex; IDA:FlyBase.::GO:0030286; C:dynein complex; IDA:FlyBase.::GO:0005828; C:kinetochore microtubule; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0031616; C:spindle pole centrosome; IDA:FlyBase. | | | | | | | | | | GO:0045502; F:dynein binding; ISS:UniProtKB. | | | | | | | | | | GO:0008088; P:axon cargo transport; IMP:FlyBase.::GO:0051299; P:centrosome separation; IMP:FlyBase.::GO:0030381; P:chorion-containing eggshell pattern formation; IMP:UniProtKB.::GO:0007303; P:cytoplasmic transport, nurse cell to oocyte; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:UniProtKB.::GO:0048142; P:germarium-derived cystoblast division; IMP:UniProtKB.::GO:0007294; P:germarium-derived oocyte fate determination; IMP:UniProtKB.::GO:0008298; P:intracellular mRNA localization; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IMP:FlyBase.::GO:0051383; P:kinetochore organization; IMP:FlyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:UniProtKB.::GO:0007405; P:neuroblast proliferation; IMP:UniProtKB.::GO:0030473; P:nuclear migration along microtubule; IGI:FlyBase.::GO:0007312; P:oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:UniProtKB.::GO:0030510; P:regulation of BMP signaling pathway; IDA:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.::GO:0043143; P:regulation of translation by machinery localization; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:FlyBase.::GO:0019827; P:stem cell maintenance; IDA:FlyBase. | 65 | Q291L9 | 411 | LIS1_DROPS Lissencephaly-1 homolog OS=Drosoph... | 230 | 0.0000000002 | 67.8 | 24 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 66 | B4GAJ1 | 411 | LIS1_DROPE Lissencephaly-1 homolog OS=Drosoph... | 230 | 0.0000000002 | 67.8 | 24 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 67 | Q8I0F4 | 419 | LIS1_DICDI Lissencephaly-1 homolog OS=Dictyos... | 243 | 0.00000006 | 59.7 | 21 | 39 | GO:0031592; C:centrosomal corona; IDA:dictyBase.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0045504; F:dynein heavy chain binding; IPI:dictyBase.::GO:0017048; F:Rho GTPase binding; IPI:dictyBase. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051642; P:centrosome localization; IMP:dictyBase.::GO:0051645; P:Golgi localization; IMP:dictyBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 68 | B5X3Z6 | 410 | LIS1A_SALSA Lissencephaly-1 homolog A OS=Salm... | 197 | 0.0000000002 | 67.8 | 26 | 39 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 69 | Q17N69 | 409 | LIS1_AEDAE Lissencephaly-1 homolog OS=Aedes a... | 44 | 0.0007 | 46.6 | 45 | 64 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 70 | B4KT48 | 411 | LIS1_DROMO Lissencephaly-1 homolog OS=Drosoph... | 230 | 0.0000000005 | 66.2 | 24 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 71 | B4MY65 | 409 | LIS1_DROWI Lissencephaly-1 homolog OS=Drosoph... | 230 | 0.0000000002 | 67.4 | 24 | 42 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 72 | Q8YV57 | 1683 | Y2124_NOSS1 Uncharacterized WD repeat-contain... | 163 | 0.000000004 | 64.7 | 26 | 45 | | | | | | | | | | | GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:InterPro. | 73 | Q2KIG2 | 334 | WDR5_BOVIN WD repeat-containing protein 5 OS=... | 206 | 0.00004 | 50.1 | 26 | 43 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 74 | Q498M4 | 334 | WDR5_RAT WD repeat-containing protein 5 OS=Ra... | 206 | 0.00004 | 50.4 | 26 | 43 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 75 | P61965 | 334 | WDR5_MOUSE WD repeat-containing protein 5 OS=... | 206 | 0.00004 | 50.4 | 26 | 43 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 76 | P61964 | 334 | WDR5_HUMAN WD repeat-containing protein 5 OS=... | 206 | 0.00004 | 50.4 | 26 | 43 | GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 77 | C5FWH1 | 461 | LIS1_ARTOC Nuclear distribution protein PAC1 ... | 282 | 0.000000000000003 | 82.8 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 78 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 149 | 0.0004 | 47.4 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 79 | A8XZJ9 | 390 | LIS1_CAEBR Lissencephaly-1 homolog OS=Caenorh... | 43 | 0.005 | 43.9 | 47 | 65 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 80 | Q0P593 | 415 | WDR69_BOVIN Outer row dynein assembly protein... | 260 | 0.00000000000001 | 80.9 | 25 | 44 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 81 | Q5RE95 | 330 | WDR5B_PONAB WD repeat-containing protein 5B O... | 206 | 0.007 | 43.1 | 28 | 41 | | | | | | | | | | | | | | | | | | | | | | 82 | Q86VZ2 | 330 | WDR5B_HUMAN WD repeat-containing protein 5B O... | 206 | 0.007 | 43.5 | 28 | 41 | | | | | | | | | | | | | | | | | | | | | | 83 | Q7ZVF0 | 416 | POC1A_DANRE POC1 centriolar protein homolog A... | 251 | 0.00000000000006 | 78.6 | 25 | 45 | | | | | | | | | | | | | | | | | | | | | | 84 | Q969H0 | 707 | FBXW7_HUMAN F-box/WD repeat-containing protei... | 134 | 0.00000004 | 60.8 | 31 | 47 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL. | 85 | Q5M786 | 334 | WDR5_XENTR WD repeat-containing protein 5 OS=... | 206 | 0.00001 | 52 | 27 | 43 | GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0035064; F:methylated histone residue binding; ISS:UniProtKB. | | | | | | | | | | GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0034968; P:histone lysine methylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 86 | Q2UGU1 | 455 | LIS1_ASPOR Nuclear distribution protein nudF ... | 137 | 0.000000000002 | 73.6 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 87 | B8N9H4 | 455 | LIS1_ASPFN Nuclear distribution protein nudF ... | 137 | 0.000000000002 | 73.6 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 88 | Q54KL5 | 335 | WDR5_DICDI WD repeat-containing protein 5 hom... | 206 | 0.00000004 | 60.1 | 29 | 46 | GO:0035097; C:histone methyltransferase complex; ISS:dictyBase. | | | | | | | | | | GO:0042393; F:histone binding; ISS:dictyBase. | | | | | | | | | | GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase. | 89 | Q09715 | 614 | TUP11_SCHPO Transcriptional repressor tup11 O... | 134 | 0.0002 | 48.9 | 28 | 44 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IGI:PomBase. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006342; P:chromatin silencing; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 90 | O75529 | 589 | TAF5L_HUMAN TAF5-like RNA polymerase II p300/... | 184 | 0.46 | 37.7 | 23 | 37 | GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. | 91 | D3BUN1 | 417 | LIS1_POLPA Lissencephaly-1 homolog OS=Polysph... | 103 | 0.000000000003 | 73.2 | 30 | 55 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. |