Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL137W
Length:
889
Number of sequences:
5887
Description:
YGL137W SEC27 SGDID:S000003105, Chr VII from 249869-249886,250087-252738, Genome Release 64-1-1, Verified ORF, "Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q9VU65    391   POC1_DROME POC1 centriolar protein homolog OS...1180.27     38.5     19     42
GO:0051297; P:centrosome organization; IMP:FlyBase.
452P52287    340   GBB3_RAT Guanine nucleotide-binding protein G...830.015     42.4     29     49
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
453P79147    340   GBB3_CANFA Guanine nucleotide-binding protein...830.016     42     29     49GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
454B9WHJ2    380   CIAO1_CANDC Probable cytosolic iron-sulfur pr...2070.000000001     64.7     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
455Q10282    305   GBB_SCHPO Guanine nucleotide-binding protein ...2930.0000005     56.2     18     38GO:0005829; C:cytosol; IDA:PomBase.::GO:0005834; C:heterotrimeric G-protein complex; TAS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0010619; P:activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway; TAS:PomBase.::GO:0031138; P:negative regulation of conjugation with cellular fusion; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
456Q9ERF3    305   WDR61_MOUSE WD repeat-containing protein 61 O...2180.0000001     57.8     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
457A5DJX5    507   LIS1_PICGU Nuclear distribution protein PAC1 ...1100.22     38.9     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
458Q75C26    328   CIAO1_ASHGO Probable cytosolic iron-sulfur pr...2220.000000001     64.3     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
459Q9C0J8    1336   WDR33_HUMAN pre-mRNA 3' end processing protei...2090.0000007     57     23     44GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006301; P:postreplication repair; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; NAS:UniProtKB.
460O60907    577   TBL1X_HUMAN F-box-like/WD repeat-containing p...1710.55     37.7     22     35GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
461P38129    798   TAF5_YEAST Transcription initiation factor TF...1640.00001     52.8     23     40GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.::GO:0005669; C:transcription factor TFIID complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0032947; F:protein complex scaffold; IMP:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IC:SGD.
462Q8IZU2    1322   WDR17_HUMAN WD repeat-containing protein 17 O...1220.0005     47.8     25     48
463Q17BB0    427   WDR12_AEDAE Ribosome biogenesis protein WDR12...2210.000000002     64.7     28     43GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.
GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
464Q10051    492   PRP19_CAEEL Pre-mRNA-processing factor 19 hom...1130.007     43.5     24     50GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
465O74319    642   TAF73_SCHPO Transcription initiation factor T...1760.0003     48.1     23     38GO:0005829; C:cytosol; IDA:PomBase.::GO:0005669; C:transcription factor TFIID complex; TAS:PomBase.
GO:0000991; F:core RNA polymerase II binding transcription factor activity; IC:PomBase.
GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IGI:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:PomBase.
466Q8K4P0    1330   WDR33_MOUSE pre-mRNA 3' end processing protei...2090.0000005     57.4     23     44GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
467P07834    779   CDC4_YEAST Cell division control protein 4 OS...2390.00003     51.6     23     41GO:0016363; C:nuclear matrix; IDA:SGD.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
468Q9UT57    608   CFD1_SCHPO Probable cytosolic Fe-S cluster as...2610.00003     51.2     23     38GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; ISS:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0016226; P:iron-sulfur cluster assembly; ISS:PomBase.
469O55106    780   STRN_MOUSE Striatin OS=Mus musculus (Mouse). ...810.002     45.4     31     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
470Q9DC48    579   PRP17_MOUSE Pre-mRNA-processing factor 17 OS=...800.008     43.5     30     51GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
471Q4R8H1    569   TBL1X_MACFA F-box-like/WD repeat-containing p...1710.57     37.4     22     35GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.::GO:0007605; P:sensory perception of sound; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
472A7TLU2    347   CIAO1_VANPO Probable cytosolic iron-sulfur pr...2970.000000002     63.9     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
473Q55DA2    333   CIAO1_DICDI Probable cytosolic iron-sulfur pr...3150.0003     47.4     21     36
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
474Q15269    919   PWP2_HUMAN Periodic tryptophan protein 2 homo...1040.0001     49.7     25     49GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0004871; F:signal transducer activity; TAS:ProtInc.
475B4JW81    331   CIAO1_DROGR Probable cytosolic iron-sulfur pr...1470.2     38.5     27     41
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
476O60508    579   PRP17_HUMAN Pre-mRNA-processing factor 17 OS=...800.008     43.5     30     51GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0031124; P:mRNA 3'-end processing; TAS:Reactome.::GO:0006406; P:mRNA export from nucleus; TAS:Reactome.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:UniProtKB.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
477Q9Y6I7    421   WSB1_HUMAN WD repeat and SOCS box-containing ...2550.54     37.4     22     37GO:0005622; C:intracellular; IDA:LIFEdb.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
478O88342    606   WDR1_MOUSE WD repeat-containing protein 1 OS=...930.005     43.9     28     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
479O43071    558   PRP17_SCHPO Pre-mRNA-processing factor 17 OS=...1761.2     36.6     24     38GO:0005681; C:spliceosomal complex; ISS:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
480B3NQR5    335   CIAO1_DROER Probable cytosolic iron-sulfur pr...1522.8     35     27     45
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
481Q03897    1148   WDR59_YEAST Maintenance of telomere capping p...2000.000000003     64.7     26     44GO:0097042; C:extrinsic to fungal-type vacuolar membrane; IDA:SGD.::GO:0035859; C:Seh1-associated complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
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