Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL137W
Length:
889
Number of sequences:
5887
Description:
YGL137W SEC27 SGDID:S000003105, Chr VII from 249869-249886,250087-252738, Genome Release 64-1-1, Verified ORF, "Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361P63247    317   GBLP_CHICK Guanine nucleotide-binding protein...2390.00000002     60.8     25     42GO:0043025; C:neuronal cell body; ISS:UniProtKB.
GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:UniProtKB.
362P63243    317   GBLP_BOVIN Guanine nucleotide-binding protein...2390.00000002     60.8     25     42GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0001891; C:phagocytic cup; ISS:UniProtKB.
GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0030292; F:protein tyrosine kinase inhibitor activity; ISS:UniProtKB.::GO:0030971; F:receptor tyrosine kinase binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0050765; P:negative regulation of phagocytosis; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0032464; P:positive regulation of protein homooligomerization; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0051302; P:regulation of cell division; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
363Q9NRL3    753   STRN4_HUMAN Striatin-4 OS=Homo sapiens (Human...2310.000002     55.5     24     37GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0070016; F:armadillo repeat domain binding; IPI:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.::GO:0051721; F:protein phosphatase 2A binding; IDA:UniProtKB.
364Q6PH57    340   GBB1_DANRE Guanine nucleotide-binding protein...830.026     41.6     30     48
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
365Q6PE01    358   SNR40_MOUSE U5 small nuclear ribonucleoprotei...2140.00003     50.8     22     40
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
366O42248    317   GBLP_DANRE Guanine nucleotide-binding protein...2000.00000002     60.5     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001525; P:angiogenesis; IMP:ZFIN.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; IMP:UniProtKB.::GO:0051302; P:regulation of cell division; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0032880; P:regulation of protein localization; IMP:UniProtKB.
367O14727    1248   APAF_HUMAN Apoptotic protease-activating fact...2660.001     47     21     41GO:0043293; C:apoptosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; IDA:UniProtKB.::GO:0006952; P:defense response; IEA:InterPro.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0097193; P:intrinsic apoptotic signaling pathway; TAS:UniProtKB.::GO:0007399; P:nervous system development; TAS:ProtInc.
368Q6CMA2    333   CIAO1_KLULA Probable cytosolic iron-sulfur pr...2040.00000000001     70.5     28     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
369B6GZA1    673   SCONB_PENCW Probable E3 ubiquitin ligase comp...1320.0000000003     67.8     33     49
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
370B5X9P2    330   CIO1A_SALSA Probable cytosolic iron-sulfur pr...2260.009     42.7     21     41
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
371P17343    340   GBB1_CAEEL Guanine nucleotide-binding protein...830.83     36.6     28     47
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040013; P:negative regulation of locomotion; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0046662; P:regulation of oviposition; IMP:WormBase.
372Q61ZF6    340   GBB1_CAEBR Guanine nucleotide-binding protein...830.83     36.6     28     47
GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
373Q7ZVA0    513   SMU1_DANRE WD40 repeat-containing protein SMU...3060.000000005     63.5     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
374Q5M7T1    339   CIAO1_RAT Probable cytosolic iron-sulfur prot...2830.000004     53.5     24     42GO:0071817; C:MMXD complex; ISS:UniProtKB.
GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
375P87177    922   YB1C_SCHPO Uncharacterized WD repeat-containi...1600.98     37     21     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0032040; C:small-subunit processome; ISS:PomBase.
GO:0030515; F:snoRNA binding; ISS:PomBase.
GO:0030490; P:maturation of SSU-rRNA; ISS:PomBase.
376Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...2560.00000000002     71.2     24     45GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
377Q9NYS7    404   WSB2_HUMAN WD repeat and SOCS box-containing ...1670.0000002     58.2     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
378Q7T2F6    423   WSB1_DANRE WD repeat and SOCS box-containing ...1133.6     34.7     29     43
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
379O88879    1249   APAF_MOUSE Apoptotic protease-activating fact...2530.000004     54.7     22     42GO:0005634; C:nucleus; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
GO:0043531; F:ADP binding; IEA:InterPro.::GO:0016505; F:apoptotic protease activator activity; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.
GO:0006952; P:defense response; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
380Q6PBD6    305   WDR61_XENTR WD repeat-containing protein 61 O...1840.016     42     23     45GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
381Q9UTC7    462   YIDC_SCHPO Uncharacterized WD repeat-containi...2030.00003     51.2     24     43GO:0005829; C:cytosol; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.
GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
382Q0V8J1    406   WSB2_BOVIN WD repeat and SOCS box-containing ...1670.0000003     57.4     23     46
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
383B6K1G6    616   CFD1_SCHJY Probable cytosolic Fe-S cluster as...753.3     35     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
384Q32LN7    305   WDR61_BOVIN WD repeat-containing protein 61 O...2180.0000003     56.6     27     42GO:0016593; C:Cdc73/Paf1 complex; ISS:UniProtKB.::GO:0055087; C:Ski complex; ISS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; ISS:UniProtKB.
GO:0080182; P:histone H3-K4 trimethylation; ISS:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0051571; P:positive regulation of histone H3-K4 methylation; ISS:UniProtKB.::GO:2001162; P:positive regulation of histone H3-K79 methylation; ISS:UniProtKB.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.
385A8Q2R5    660   WDR48_BRUMA WD repeat-containing protein 48 h...1880.00001     52.8     24     41
386B5X212    333   CIO1B_SALSA Probable cytosolic iron-sulfur pr...2280.012     42.4     21     40
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
387Q9UTN4    509   PFS2_SCHPO Polyadenylation factor subunit 2 O...1560.0001     49.3     28     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:PomBase.
388P42527    1146   MHCKA_DICDI Myosin heavy chain kinase A OS=Di...2410.00001     52.8     23     42GO:0005938; C:cell cortex; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016887; F:ATPase activity; IDA:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase.
GO:0051764; P:actin crosslink formation; IDA:dictyBase.::GO:0051017; P:actin filament bundle assembly; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IDA:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0051260; P:protein homooligomerization; IDA:dictyBase.
389Q05048    431   CSTF1_HUMAN Cleavage stimulation factor subun...1740.0003     48.1     22     47GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.
GO:0006379; P:mRNA cleavage; TAS:ProtInc.::GO:0006378; P:mRNA polyadenylation; TAS:ProtInc.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; TAS:Reactome.::GO:0006369; P:termination of RNA polymerase II transcription; TAS:Reactome.
390Q9P7I3    651   MDV1_SCHPO Mitochondrial division protein 1 O...2900.00000000006     69.7     28     43GO:0030015; C:CCR4-NOT core complex; NAS:PomBase.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase.
GO:0051020; F:GTPase binding; NAS:PomBase.
GO:0000266; P:mitochondrial fission; ISS:PomBase.::GO:0000002; P:mitochondrial genome maintenance; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:PomBase.::GO:0006354; P:transcription elongation, DNA-dependent; IC:PomBase.
391B4LJT7    331   CIAO1_DROVI Probable cytosolic iron-sulfur pr...1470.095     39.7     27     41
GO:0016226; P:iron-sulfur cluster assembly; ISS:UniProtKB.
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