Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL125W
Length:
600
Number of sequences:
5887
Description:
YGL125W MET13 SGDID:S000003093, Chr VII from 272520-274322, Genome Release 64-1-1, Verified ORF, "Major isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53128    600   MTHR2_YEAST Methylenetetrahydrofolate reducta...6000     1249     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009086; P:methionine biosynthetic process; IMP:SGD.
2Q10258    603   MTHR1_SCHPO Methylenetetrahydrofolate reducta...5910     560     49     66GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IDA:PomBase.
GO:0009086; P:methionine biosynthetic process; IDA:PomBase.
3Q75HE6    594   MTHR_ORYSJ Probable methylenetetrahydrofolate...6002e-169     502     45     62
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
4Q9SE94    593   MTHR1_MAIZE Methylenetetrahydrofolate reducta...6006e-168     498     44     62
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
5Q9SE60    592   MTHR1_ARATH Methylenetetrahydrofolate reducta...5996e-162     483     43     62GO:0005829; C:cytosol; IDA:TAIR.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
6O80585    594   MTHR2_ARATH Methylenetetrahydrofolate reducta...5998e-162     483     44     60GO:0005829; C:cytosol; IDA:TAIR.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
7P42898    656   MTHR_HUMAN Methylenetetrahydrofolate reductas...5999e-153     461     42     60GO:0005829; C:cytosol; TAS:Reactome.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; TAS:Reactome.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
GO:0008015; P:blood circulation; TAS:ProtInc.::GO:0046655; P:folic acid metabolic process; TAS:Reactome.::GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.
8Q60HE5    656   MTHR_MACFA Methylenetetrahydrofolate reductas...5924e-151     457     42     60
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
9Q5I598    655   MTHR_BOVIN Methylenetetrahydrofolate reductas...5992e-150     455     41     61
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
10Q9WU20    654   MTHR_MOUSE Methylenetetrahydrofolate reductas...5992e-149     453     41     60
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IMP:MGI.
GO:0009086; P:methionine biosynthetic process; IMP:MGI.
11Q17693    663   MTHR_CAEEL Probable methylenetetrahydrofolate...5939e-125     389     38     56
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0006555; P:methionine metabolic process; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
12O74927    641   MTHR2_SCHPO Methylenetetrahydrofolate reducta...6389e-116     365     36     55GO:0005737; C:cytoplasm; ISS:PomBase.
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IDA:PomBase.
GO:0009086; P:methionine biosynthetic process; IDA:PomBase.
13P46151    657   MTHR1_YEAST Methylenetetrahydrofolate reducta...2605e-49     185     39     58
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006555; P:methionine metabolic process; IEA:InterPro.
14O67422    296   METF_AQUAE 5,10-methylenetetrahydrofolate red...2981e-59     207     38     57
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
15O54235    307   METF_STRLI 5,10-methylenetetrahydrofolate red...2893e-47     173     36     52
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
16P71319    298   METF_PECCC 5,10-methylenetetrahydrofolate red...2933e-43     161     33     54
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
17P0AEZ2    296   METF_SHIFL 5,10-methylenetetrahydrofolate red...2912e-41     156     32     53
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
18P0AEZ1    296   METF_ECOLI 5,10-methylenetetrahydrofolate red...2912e-41     156     32     53
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IDA:EcoCyc.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
19P11003    296   METF_SALTY 5,10-methylenetetrahydrofolate red...2912e-40     153     32     53
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
20Q9JZQ3    292   METF_NEIMB 5,10-methylenetetrahydrofolate red...2878e-38     145     32     50
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
21P45208    292   METF_HAEIN 5,10-methylenetetrahydrofolate red...3019e-36     140     31     49
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
22Q89B13    295   METF_BUCBP 5,10-methylenetetrahydrofolate red...2944e-35     138     31     49
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
23P57154    292   METF_BUCAI 5,10-methylenetetrahydrofolate red...2666e-31     126     32     53
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
24Q8KA62    292   METF_BUCAP 5,10-methylenetetrahydrofolate red...2832e-26     113     30     51
GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
25O06745    612   YITJ_BACSU Bifunctional homocysteine S-methyl...1920.001     45.4     24     45
GO:0008898; F:homocysteine S-methyltransferase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004489; F:methylenetetrahydrofolate reductase (NADPH) activity; IEA:EC.
GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
26Q8EU99    220   KITH_MYCPE Thymidine kinase OS=Mycoplasma pen...353.8     33.5     34     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004797; F:thymidine kinase activity; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
records
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