Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL116W
Length:
610
Number of sequences:
5887
Description:
YGL116W CDC20 SGDID:S000003084, Chr VII from 289809-291641, Genome Release 64-1-1, Verified ORF, "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P26309    610   CDC20_YEAST APC/C activator protein CDC20 OS=...6100     1267     100     100GO:0005680; C:anaphase-promoting complex; IPI:SGD.::GO:0033597; C:mitotic checkpoint complex; IDA:SGD.
GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IMP:SGD.::GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0007133; P:meiotic anaphase I; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031577; P:spindle checkpoint; IPI:SGD.
2P78972    488   SLP1_SCHPO WD repeat-containing protein slp1 ...4233e-113     354     44     64GO:0032153; C:cell division site; IDA:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0033597; C:mitotic checkpoint complex; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033314; P:mitotic cell cycle DNA replication checkpoint; IGI:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IGI:PomBase.
3Q54MZ3    499   CDC20_DICDI Anaphase-promoting complex subuni...3417e-82     272     40     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
4Q62623    499   CDC20_RAT Cell division cycle protein 20 homo...4272e-77     261     37     55GO:0005813; C:centrosome; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:RGD.
5Q12834    499   CDC20_HUMAN Cell division cycle protein 20 ho...4532e-77     260     35     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
6Q5H7C0    499   CDC20_PIG Cell division cycle protein 20 homo...4343e-77     260     36     55GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; ISS:UniProtKB.
7Q9JJ66    499   CDC20_MOUSE Cell division cycle protein 20 ho...3201e-76     258     40     61GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090129; P:positive regulation of synapse maturation; IDA:UniProtKB.::GO:0031915; P:positive regulation of synaptic plasticity; IDA:UniProtKB.::GO:0040020; P:regulation of meiosis; IGI:MGI.
8Q8L3Z8    483   FZR2_ARATH Protein FIZZY-RELATED 2 OS=Arabido...3141e-75     255     41     60
GO:0005515; F:protein binding; IPI:TAIR.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016049; P:cell growth; IMP:TAIR.::GO:0042023; P:DNA endoreduplication; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010091; P:trichome branching; IMP:TAIR.
9Q8LPL5    481   FZR3_ARATH Protein FIZZY-RELATED 3 OS=Arabido...3076e-74     250     41     60
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
10Q8VZS9    475   FZR1_ARATH Protein FIZZY-RELATED 1 OS=Arabido...3291e-73     250     40     59GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032877; P:positive regulation of DNA endoreduplication; IMP:TAIR.
11O13286    556   SRW1_SCHPO WD repeat-containing protein srw1 ...3693e-73     251     38     56GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; TAS:PomBase.::GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IC:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.
12O94423    421   MFR1_SCHPO Meiotic fizzy-related protein 1 OS...4303e-67     231     33     52GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IGI:PomBase.::GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0007138; P:meiotic anaphase II; IMP:PomBase.
13Q54KM3    754   CDH1_DICDI Anaphase-promoting complex subunit...3475e-65     232     38     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
14Q9R1K5    493   FZR_MOUSE Fizzy-related protein homolog OS=Mu...3162e-64     225     39     58
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0070306; P:lens fiber cell differentiation; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0090344; P:negative regulation of cell aging; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; ISS:UniProtKB.::GO:0040020; P:regulation of meiosis; IDA:MGI.
15Q9UM11    496   FZR_HUMAN Fizzy-related protein homolog OS=Ho...3162e-64     225     39     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0045732; P:positive regulation of protein catabolic process; IGI:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070979; P:protein K11-linked ubiquitination; TAS:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.
16P53197    566   CDH1_YEAST APC/C activator protein CDH1 OS=Sa...3164e-59     213     36     57GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0030332; F:cyclin binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010697; P:negative regulation of spindle pole body separation; IMP:SGD.::GO:2000600; P:positive regulation of cyclin catabolic process; IDA:SGD.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0008361; P:regulation of cell size; IMP:SGD.
17Q86Y33    519   CD20B_HUMAN Cell division cycle protein 20 ho...3174e-43     166     33     50
18O94411    509   MFR2_SCHPO Meiotic fizzy-related protein 2 OS...3302e-37     149     30     50GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
19Q09786    535   YA98_SCHPO Uncharacterized WD repeat-containi...2482e-37     149     38     55GO:0043234; C:protein complex; NAS:PomBase.
20P50082    593   AMA1_YEAST Meiosis-specific APC/C activator p...3592e-34     141     28     47GO:0005680; C:anaphase-promoting complex; IPI:SGD.
GO:0008047; F:enzyme activator activity; IMP:SGD.
GO:0030476; P:ascospore wall assembly; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007127; P:meiosis I; IMP:SGD.::GO:0045732; P:positive regulation of protein catabolic process; IMP:SGD.
21Q09373    507   FZY1_CAEEL WD repeat-containing protein fzy-1...3301e-31     132     29     44GO:0000793; C:condensed chromosome; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007091; P:mitotic metaphase/anaphase transition; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
22Q8YRI1    1526   YY46_NOSS1 Uncharacterized WD repeat-containi...1830.15     38.9     19     43
23Q54KL5    335   WDR5_DICDI WD repeat-containing protein 5 hom...2770.0000000000002     75.1     25     42GO:0035097; C:histone methyltransferase complex; ISS:dictyBase.
GO:0042393; F:histone binding; ISS:dictyBase.
GO:0051568; P:histone H3-K4 methylation; ISS:dictyBase.
24Q8H0T9    837   KTNB1_ARATH Katanin p80 WD40 repeat-containin...2500.000000000002     74.3     26     44GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.
25Q8YV57    1683   Y2124_NOSS1 Uncharacterized WD repeat-contain...1570.13     39.3     24     41
GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
26Q00808    1356   HETE1_PODAS Vegetative incompatibility protei...2910.000000005     63.2     21     41
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
27Q5ZIU8    657   KTNB1_CHICK Katanin p80 WD40-containing subun...1830.64     36.6     23     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
28P0CS48    473   PRP46_CRYNJ Pre-mRNA-splicing factor PRP46 OS...2860.00000000004     69.3     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
29P0CS49    473   PRP46_CRYNB Pre-mRNA-splicing factor PRP46 OS...2860.00000000004     68.9     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
30Q4V7Y7    655   KTNB1_XENLA Katanin p80 WD40-containing subun...1802.3     35     23     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
31Q8YTC2    1258   Y2800_NOSS1 Uncharacterized WD repeat-contain...3050.000008     52.8     20     40
GO:0043531; F:ADP binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.
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