UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL116W

Length:

610

Number of sequences:

5887

Description:

YGL116W CDC20 SGDID:S000003084, Chr VII from 289809-291641, Genome Release 64-1-1, Verified ORF, "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	Q9V3J8	361	WDS_DROME Protein will die slowly OS=Drosophi...	193	0.061	39.7	23	40	GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
									GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
62	B7PS00	411	LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes ...	312	0.005	43.1	21	39	GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
63	Q9NVX2	485	NLE1_HUMAN Notchless protein homolog 1 OS=Hom...	147	3.5	34.3	20	32	GO:0005730; C:nucleolus; IDA:HPA.
64	C4YFX2	511	TUP1_CANAW Transcriptional repressor TUP1 OS=...	76	5.5	33.5	26	54
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65	P0CY34	512	TUP1_CANAL Transcriptional repressor TUP1 OS=...	76	5.5	33.5	26	54	GO:0005625; C:soluble fraction; IDA:CGD.
									GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
66	Q68FJ6	363	PK1IP_XENLA p21-activated protein kinase-inte...	206	0.0000003	56.6	27	40	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
67	C5FP68	674	SCONB_ARTOC Probable E3 ubiquitin ligase comp...	99	0.78	36.6	30	47
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68	D4AM37	663	SCONB_ARTBC Probable E3 ubiquitin ligase comp...	99	4	34.3	29	44
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
69	Q7ZVF0	416	POC1A_DANRE POC1 centriolar protein homolog A...	300	2.5	34.7	19	36
70	O88879	1249	APAF_MOUSE Apoptotic protease-activating fact...	224	2.5	35	22	42	GO:0005634; C:nucleus; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0016505; F:apoptotic protease activator activity; IPI:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.
									GO:0006952; P:defense response; IEA:InterPro.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
71	D4D8P3	663	SCONB_TRIVH Probable E3 ubiquitin ligase comp...	99	4	34.3	29	44
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72	Q9EPV5	1249	APAF_RAT Apoptotic protease-activating factor...	217	0.43	37.4	24	41	GO:0043293; C:apoptosome; IDA:RGD.
									GO:0043531; F:ADP binding; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.
									GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0010659; P:cardiac muscle cell apoptotic process; IMP:RGD.::GO:0030154; P:cell differentiation; IEP:RGD.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0006952; P:defense response; IEA:InterPro.::GO:0034349; P:glial cell apoptotic process; IEP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.
73	Q9FLX9	473	NLE1_ARATH Notchless protein homolog OS=Arabi...	287	3.3	34.3	19	37	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
74	Q7T394	410	LIS1A_DANRE Lissencephaly-1 homolog A OS=Dani...	299	0.0000006	55.8	21	41	GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
									GO:0048854; P:brain morphogenesis; IMP:ZFIN.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
75	O13637	1224	SEC31_SCHPO Protein transport protein sec31 O...	172	0.0000006	56.6	26	48	GO:0030127; C:COPII vesicle coat; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:PomBase.::GO:0006886; P:intracellular protein transport; IMP:PomBase.::GO:0006998; P:nuclear envelope organization; IMP:PomBase.
76	Q5JTN6	314	WDR38_HUMAN WD repeat-containing protein 38 O...	177	0.043	40	23	41
77	Q9C0J8	1336	WDR33_HUMAN pre-mRNA 3' end processing protei...	134	6.4	33.5	19	38	GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006301; P:postreplication repair; NAS:UniProtKB.::GO:0007283; P:spermatogenesis; NAS:UniProtKB.
78	Q9XGN1	341	TTG1_ARATH Protein TRANSPARENT TESTA GLABRA 1...	221	0.0000007	55.5	24	45	GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0003677; F:DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0009957; P:epidermal cell fate specification; IMP:TAIR.::GO:0032880; P:regulation of protein localization; IMP:TAIR.::GO:0009733; P:response to auxin stimulus; IEP:TAIR.::GO:0009723; P:response to ethylene stimulus; IEP:TAIR.::GO:0010026; P:trichome differentiation; IMP:TAIR.
79	Q5XI13	445	GRWD1_RAT Glutamate-rich WD repeat-containing...	140	0.0000007	55.5	30	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
80	Q5BJ90	423	WDR12_XENTR Ribosome biogenesis protein wdr12...	96	4	33.9	30	46	GO:0005654; C:nucleoplasm; ISS:UniProtKB.::GO:0070545; C:PeBoW complex; ISS:UniProtKB.::GO:0030687; C:preribosome, large subunit precursor; ISS:UniProtKB.
									GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.::GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:UniProtKB.
81	Q3Y8L7	446	WDR69_CHLRE Outer row dynein assembly protein...	228	3.1	34.3	19	37	GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
82	Q8K4P0	1330	WDR33_MOUSE pre-mRNA 3' end processing protei...	170	7.6	33.5	19	36	GO:0005581; C:collagen; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
83	Q5FVN8	476	WSDU1_RAT WD repeat, SAM and U-box domain-con...	238	0.34	37.4	23	39	GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
84	P20053	465	PRP4_YEAST U4/U6 small nuclear ribonucleoprot...	136	2.9	34.7	21	38	GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0000398; P:nuclear mRNA splicing, via spliceosome; IPI:SGD.
85	Q5BE22	452	PRP46_EMENI Pre-mRNA-splicing factor prp46 OS...	155	0.15	38.5	23	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
86	Q5ZKU8	369	PK1IP_CHICK p21-activated protein kinase-inte...	217	0.000002	53.9	27	40	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
87	Q00659	678	SCONB_EMENI Probable E3 ubiquitin ligase comp...	99	5.8	33.5	30	45
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
88	Q4WT34	453	PRP46_ASPFU Pre-mRNA-splicing factor prp46 OS...	166	0.054	40	23	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
89	Q39190	479	PRL2_ARATH Protein pleiotropic regulator PRL2...	175	0.45	37	21	40	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.
									GO:0005515; F:protein binding; IPI:TAIR.
90	Q9D0I6	474	WSDU1_MOUSE WD repeat, SAM and U-box domain-c...	217	4	33.9	23	37	GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
									GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
91	Q8BX17	1502	GEMI5_MOUSE Gem-associated protein 5 OS=Mus m...	73	2.5	35	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0017069; F:snRNA binding; ISS:UniProtKB.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.

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