Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL116W
Length:
610
Number of sequences:
5887
Description:
YGL116W CDC20 SGDID:S000003084, Chr VII from 289809-291641, Genome Release 64-1-1, Verified ORF, "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181B8NGT5    706   SCONB_ASPFN Probable E3 ubiquitin ligase comp...1031.7     35.4     30     45
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
182B4N0L0    322   EIF3I_DROWI Eukaryotic translation initiation...2120.00004     49.7     23     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
183P0CS47    713   PFS2_CRYNB Polyadenylation factor subunit 2 O...1500.3     37.7     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
184Q54PE0    922   PWP2_DICDI Periodic tryptophan protein 2 homo...1990.00004     50.4     23     45GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005730; C:nucleolus; ISS:dictyBase.
GO:0030515; F:snoRNA binding; ISS:dictyBase.
GO:0006364; P:rRNA processing; ISS:dictyBase.
185Q05B17    678   WDR48_XENTR WD repeat-containing protein 48 O...1780.011     42.4     24     42GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
186Q9BQ67    446   GRWD1_HUMAN Glutamate-rich WD repeat-containi...1400.00004     50.1     29     45GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
187Q29RH4    351   THOC3_BOVIN THO complex subunit 3 OS=Bos taur...2100.00004     49.7     21     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
188Q9BZK7    514   TBL1R_HUMAN F-box-like/WD repeat-containing p...1110.034     40.8     32     44GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
189P0CS46    712   PFS2_CRYNJ Polyadenylation factor subunit 2 O...1720.36     37.7     23     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
190Q8BHJ5    514   TBL1R_MOUSE F-box-like/WD repeat-containing p...1110.037     40.8     32     44
GO:0003714; F:transcription corepressor activity; IMP:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
191Q96J01    351   THOC3_HUMAN THO complex subunit 3 OS=Homo sap...2100.00005     49.7     21     40GO:0000346; C:transcription export complex; IDA:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
192P78706    604   RCO1_NEUCR Transcriptional repressor rco-1 OS...2180.0004     47     22     42
GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
193Q7ZW33    517   UTP15_DANRE U3 small nucleolar RNA-associated...1730.51     37     23     41GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
194Q8VE80    351   THOC3_MOUSE THO complex subunit 3 OS=Mus musc...2100.00005     49.7     21     40
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
195Q9BQ87    522   TBL1Y_HUMAN F-box-like/WD repeat-containing p...2250.00005     50.1     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
196Q5F3K4    678   WDR48_CHICK WD repeat-containing protein 48 O...1780.064     40     23     42GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.
197Q3ULA2    605   FBW1A_MOUSE F-box/WD repeat-containing protei...2041.8     35.4     20     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB.
GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.
GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
198Q6PAX7    607   WDR1B_XENLA WD repeat-containing protein 1-B ...1630.29     37.7     27     42GO:0005884; C:actin filament; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.
GO:0030043; P:actin filament fragmentation; ISS:UniProtKB.
199P16649    713   TUP1_YEAST General transcriptional corepresso...2460.008     43.1     22     41GO:0017053; C:transcriptional repressor complex; IDA:SGD.
GO:0042393; F:histone binding; IDA:SGD.::GO:0042826; F:histone deacetylase binding; IDA:SGD.::GO:0036033; F:mediator complex binding; IDA:SGD.::GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:SGD.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0043486; P:histone exchange; IMP:SGD.::GO:0035955; P:negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0001198; P:negative regulation of mating-type specific transcription from RNA polymerase II promoter; IMP:SGD.::GO:0000433; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:SGD.::GO:0007070; P:negative regulation of transcription from RNA polymerase II promoter during mitosis; IMP:SGD.::GO:0016584; P:nucleosome positioning; IDA:SGD.::GO:2000531; P:regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:2001020; P:regulation of response to DNA damage stimulus; IMP:SGD.::GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IMP:SGD.::GO:0061392; P:regulation of transcription from RNA polymerase II promoter in response to osmotic stress; IMP:SGD.
200Q90ZL4    410   LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus...1660.79     36.2     20     42GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
201Q5RD06    451   POC1B_PONAB POC1 centriolar protein homolog B...1310.24     38.1     23     42GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.
GO:0042384; P:cilium assembly; ISS:UniProtKB.
202Q9DAW6    521   PRP4_MOUSE U4/U6 small nuclear ribonucleoprot...1430.018     41.6     24     41GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
203Q2UF60    1273   SEC31_ASPOR Protein transport protein sec31 O...870.18     38.9     29     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
204A1C7E4    700   SCONB_ASPCL Probable E3 ubiquitin ligase comp...976.1     33.5     28     43
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
205Q4RJN5    410   LIS1_TETNG Lissencephaly-1 homolog OS=nigrovi...1662.2     34.7     19     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
206A7MB12    519   UTP15_BOVIN U3 small nucleolar RNA-associated...1883.4     34.3     20     39GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
207Q7SYD5    1254   SC31A_DANRE Protein transport protein Sec31A ...1700.00006     50.1     25     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0012507; C:ER to Golgi transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
208Q13216    396   ERCC8_HUMAN DNA excision repair protein ERCC-...1570.00007     49.3     25     46GO:0031464; C:Cul4A-RING ubiquitin ligase complex; IDA:UniProtKB.::GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000109; C:nucleotide-excision repair complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0032403; F:protein complex binding; IDA:UniProtKB.
GO:0045739; P:positive regulation of DNA repair; IMP:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0006979; P:response to oxidative stress; IDA:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:UniProtKB.
209Q4V8C4    328   WDR5B_RAT WD repeat-containing protein 5B OS=...1910.009     42.4     25     42
210Q9W5Z5    427   WSB1_TAKRU WD repeat and SOCS box-containing ...1960.00007     49.3     23     38
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
211Q9Y297    605   FBW1A_HUMAN F-box/WD repeat-containing protei...2040.84     36.2     20     40GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB.
GO:0046983; F:protein dimerization activity; IEA:InterPro.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
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