Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL097W
Length:
482
Number of sequences:
5887
Description:
YGL097W SRM1 SGDID:S000003065, Chr VII from 321782-323230, Genome Release 64-1-1, Verified ORF, "Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P21827    482   RCC1_YEAST Guanine nucleotide exchange factor...4820     1006     100     100GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; IMP:SGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.::GO:0000054; P:ribosomal subunit export from nucleus; IMP:SGD.::GO:0006407; P:rRNA export from nucleus; IMP:SGD.
2P52499    464   RCC1_CANAX Protein RCC1 OS=Candida albicans (...4496e-151     446     53     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
3P28745    539   RCC1_SCHPO Protein pim1 OS=Schizosaccharomyce...4354e-100     317     39     59GO:0000790; C:nuclear chromatin; NAS:PomBase.
GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IGI:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:PomBase.::GO:0006406; P:mRNA export from nucleus; IMP:PomBase.::GO:0031291; P:Ran protein signal transduction; IGI:PomBase.::GO:0060623; P:regulation of chromosome condensation; IGI:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.::GO:0006407; P:rRNA export from nucleus; ISS:PomBase.::GO:0090307; P:spindle assembly involved in mitosis; TAS:PomBase.
4P25183    424   RCC1_XENLA Regulator of chromosome condensati...4832e-42     161     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
5P23800    421   RCC1_MESAU Regulator of chromosome condensati...4639e-41     156     27     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB.
6Q8VE37    421   RCC1_MOUSE Regulator of chromosome condensati...4642e-40     155     27     45GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031492; F:nucleosomal DNA binding; ISS:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; ISS:UniProtKB.
7P18754    421   RCC1_HUMAN Regulator of chromosome condensati...4633e-40     154     27     46GO:0000794; C:condensed nuclear chromosome; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IMP:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007052; P:mitotic spindle organization; IDA:UniProtKB.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:UniProtKB.::GO:0051225; P:spindle assembly; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
8P25171    547   RCC1_DROME Regulator of chromosome condensati...4741e-36     145     28     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007346; P:regulation of mitotic cell cycle; IDA:UniProtKB.::GO:0050767; P:regulation of neurogenesis; IMP:FlyBase.::GO:0046822; P:regulation of nucleocytoplasmic transport; IMP:FlyBase.
9Q6PAV2    1057   HERC4_MOUSE Probable E3 ubiquitin-protein lig...2280.0001     48.1     23     38GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; TAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.
10Q5GLZ8    1057   HERC4_HUMAN Probable E3 ubiquitin-protein lig...2280.00009     48.9     23     38GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
11Q5PQN1    1057   HERC4_RAT Probable E3 ubiquitin-protein ligas...2280.00008     48.9     23     38GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.
12Q18211    569   RCC1_CAEEL Regulator of chromosome condensati...4192e-22     104     25     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016246; P:RNA interference; IMP:WormBase.
13Q15034    1050   HERC3_HUMAN Probable E3 ubiquitin-protein lig...1660.0000000004     65.9     28     46GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
14Q9N1T2    1003   RPGR_CANFA X-linked retinitis pigmentosa GTPa...4110.0000001     58.2     22     41GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB.
15Q15751    4861   HERC1_HUMAN Probable E3 ubiquitin-protein lig...2170.0000000006     65.9     27     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; TAS:ProtInc.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; TAS:ProtInc.
GO:0006464; P:protein modification process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
16Q9VR91    4912   HERC2_DROME Probable E3 ubiquitin-protein lig...2610.0001     48.5     23     40GO:0005622; C:intracellular; IEA:InterPro.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
17Q9R0X5    1001   RPGR_MOUSE X-linked retinitis pigmentosa GTPa...3670.000000002     63.9     25     44GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005929; C:cilium; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB.
18Q4U2R1    4836   HERC2_MOUSE E3 ubiquitin-protein ligase HERC2...1040.012     42.4     30     42GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0020037; F:heme binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI.
19Q8IVU3    1022   HERC6_HUMAN Probable E3 ubiquitin-protein lig...2360.42     37     23     36GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
20O95714    4834   HERC2_HUMAN E3 ubiquitin-protein ligase HERC2...2920.00000003     60.5     24     42GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; NAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; NAS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
21Q8K1R7    984   NEK9_MOUSE Serine/threonine-protein kinase Ne...2960.00000008     58.5     22     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
22Q8TD19    979   NEK9_HUMAN Serine/threonine-protein kinase Ne...2550.00000004     59.7     23     41GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
23Q7ZZC8    944   NEK9_XENLA Serine/threonine-protein kinase Ne...2400.000000001     64.7     26     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
24Q8SSY6    1887   SPKUL_DICDI Bifunctional serine/threonine-pro...777.1     33.1     29     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
25Q5RCZ7    551   RCBT2_PONAB RCC1 and BTB domain-containing pr...1880.003     43.9     23     45
26O95199    551   RCBT2_HUMAN RCC1 and BTB domain-containing pr...1880.003     43.9     23     45
GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:ProtInc.
27Q92834    1020   RPGR_HUMAN X-linked retinitis pigmentosa GTPa...1510.00002     51.2     23     49GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; IEA:UniProtKB-SubCell.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; TAS:ProtInc.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IMP:UniProtKB.
28Q9UGK8    458   SRGEF_HUMAN Secretion-regulating guanine nucl...2800.00000004     59.3     24     38GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005087; F:Ran guanyl-nucleotide exchange factor activity; TAS:UniProtKB.
GO:0050709; P:negative regulation of protein secretion; IDA:HGNC.::GO:0007165; P:signal transduction; TAS:UniProtKB.
29Q6P798    551   RCBT2_RAT RCC1 and BTB domain-containing prot...1940.0006     45.8     24     45
30Q80YD6    464   SRGEF_MOUSE Secretion-regulating guanine nucl...1830.00000006     58.5     27     41GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
31Q54Q89    487   RCCDC_DICDI RCC1 repeat-containing protein DD...2210.23     37.7     24     40
records
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