Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL086W
Length:
749
Number of sequences:
5887
Description:
YGL086W MAD1 SGDID:S000003054, Chr VII from 347119-349368, Genome Release 64-1-1, Verified ORF, "Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40957    749   MAD1_YEAST Spindle assembly checkpoint compon...7490     1485     100     100GO:0000776; C:kinetochore; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070683; P:mitotic cell cycle G2/M transition decatenation checkpoint; IGI:SGD.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:SGD.::GO:0006913; P:nucleocytoplasmic transport; IGI:SGD.
2Q6CMM2    648   MAD1_KLULA Spindle assembly checkpoint compon...7115e-168     506     44     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
3Q874L7    674   MAD1_KLUDE Spindle assembly checkpoint compon...7232e-156     477     40     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
4Q754Z1    659   MAD1_ASHGO Spindle assembly checkpoint compon...840.0000000006     66.2     40     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
5Q6FS63    657   MAD1_CANGA Spindle assembly checkpoint compon...7162e-123     390     39     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
6Q6C452    704   MAD1_YARLI Spindle assembly checkpoint compon...7662e-27     122     22     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
7Q6BSY1    669   MAD1_DEBHA Spindle assembly checkpoint compon...7594e-27     121     24     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
8P87169    689   MAD1_SCHPO Spindle assembly checkpoint compon...3341e-18     94.7     28     49GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:PomBase.
9Q15149    4684   PLEC_HUMAN Plectin OS=Homo sapiens (Human). G...2510.058     40.8     20     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.
10Q10165    923   CNT6_SCHPO Probable ribosylation factor GTPas...1080.078     40     29     56GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:PomBase.
11P78559    2803   MAP1A_HUMAN Microtubule-associated protein 1A...2290.095     40     21     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005875; C:microtubule associated complex; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; NAS:ProtInc.
12P30427    4687   PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ...2540.21     38.9     20     44GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD.
GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD.
13Q03427    621   LAMC_DROME Lamin-C OS=Drosophila melanogaster...920.32     38.1     32     54GO:0005638; C:lamin filament; NAS:FlyBase.::GO:0070732; C:spindle envelope; IDA:FlyBase.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0031081; P:nuclear pore distribution; IMP:FlyBase.
14Q9Y6D9    718   MD1L1_HUMAN Mitotic spindle assembly checkpoi...7520.4     37.7     20     40GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005813; C:centrosome; NAS:UniProtKB.::GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; NAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000090; P:mitotic anaphase; NAS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000089; P:mitotic metaphase; NAS:UniProtKB.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0000093; P:mitotic telophase; NAS:UniProtKB.
15Q99323    2057   MYSN_DROME Myosin heavy chain, non-muscle OS=...1590.86     37     28     49GO:0045179; C:apical cortex; TAS:FlyBase.::GO:0032154; C:cleavage furrow; IDA:FlyBase.::GO:0016460; C:myosin II complex; IDA:FlyBase.::GO:0016461; C:unconventional myosin complex; NAS:FlyBase.::GO:0030018; C:Z disc; IDA:FlyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; ISS:FlyBase.::GO:0032027; F:myosin light chain binding; IPI:FlyBase.
GO:0007496; P:anterior midgut development; IMP:FlyBase.::GO:0035017; P:cuticle pattern formation; IMP:FlyBase.::GO:0000910; P:cytokinesis; IMP:FlyBase.::GO:0046664; P:dorsal closure, amnioserosa morphology change; IMP:FlyBase.::GO:0046663; P:dorsal closure, leading edge cell differentiation; IMP:FlyBase.::GO:0007395; P:dorsal closure, spreading of leading edge cells; IMP:FlyBase.::GO:0045200; P:establishment of neuroblast polarity; TAS:FlyBase.::GO:0001736; P:establishment of planar polarity; NAS:FlyBase.::GO:0045184; P:establishment of protein localization; IMP:FlyBase.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0035317; P:imaginal disc-derived wing hair organization; IGI:FlyBase.::GO:0070986; P:left/right axis specification; IMP:FlyBase.::GO:0007443; P:Malpighian tubule morphogenesis; IMP:FlyBase.::GO:0006936; P:muscle contraction; IMP:FlyBase.::GO:0031036; P:myosin II filament assembly; IDA:FlyBase.::GO:0007297; P:ovarian follicle cell migration; TAS:FlyBase.::GO:0051259; P:protein oligomerization; IDA:FlyBase.::GO:0035159; P:regulation of tube length, open tracheal system; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0045214; P:sarcomere organization; IMP:FlyBase.
16Q21313    3672   EPI1_CAEEL Laminin-like protein epi-1 OS=Caen...2120.94     37     18     48GO:0005604; C:basement membrane; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:InterPro.
17Q9JMH9    2050   MY18A_MOUSE Unconventional myosin-XVIIIa OS=M...1370.95     36.6     26     50GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
18B0K0J1    423   AROA_THEPX 3-phosphoshikimate 1-carboxyvinylt...1401.4     35.8     24     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:EC.
GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
19B0K928    423   AROA_THEP3 3-phosphoshikimate 1-carboxyvinylt...1401.4     35.8     24     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:EC.
GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
20C8ZH37    300   RRP36_YEAS8 rRNA biogenesis protein RRP36 OS=...982.6     34.7     32     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
21B5VSG4    300   RRP36_YEAS6 rRNA biogenesis protein RRP36 OS=...982.6     34.7     32     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
22B3LJV1    300   RRP36_YEAS1 rRNA biogenesis protein RRP36 OS=...982.6     34.7     32     53GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
23P24043    3122   LAMA2_HUMAN Laminin subunit alpha-2 OS=Homo s...1902.8     35.4     22     45GO:0005606; C:laminin-1 complex; IEA:InterPro.
GO:0005102; F:receptor binding; IEA:InterPro.::GO:0005198; F:structural molecule activity; TAS:ProtInc.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030155; P:regulation of cell adhesion; IEA:InterPro.::GO:0030334; P:regulation of cell migration; IEA:InterPro.::GO:0045995; P:regulation of embryonic development; IEA:InterPro.
24P08799    2116   MYS2_DICDI Myosin-2 heavy chain OS=Dictyostel...1194.1     34.7     27     53GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005826; C:actomyosin contractile ring; IDA:dictyBase.::GO:0032009; C:early phagosome; IDA:dictyBase.::GO:0032982; C:myosin filament; IDA:dictyBase.::GO:0016460; C:myosin II complex; IDA:dictyBase.::GO:0001931; C:uropod; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0042803; F:protein homodimerization activity; IDA:dictyBase.
GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0032060; P:bleb assembly; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0030038; P:contractile actin filament bundle assembly; IMP:dictyBase.::GO:0030866; P:cortical actin cytoskeleton organization; IDA:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0060328; P:cytoplasmic actin-based contraction involved in forward cell motility; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0031034; P:myosin filament assembly; IDA:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0008104; P:protein localization; IMP:dictyBase.::GO:0031270; P:pseudopodium retraction; IMP:dictyBase.::GO:0034461; P:uropod retraction; IMP:dictyBase.
25Q92614    2054   MY18A_HUMAN Unconventional myosin-XVIIIa OS=H...844.4     34.7     29     57GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008094; F:DNA-dependent ATPase activity; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:ProtInc.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0006259; P:DNA metabolic process; IEA:InterPro.
26Q8K389    1822   CK5P2_MOUSE CDK5 regulatory subunit-associate...844.8     34.3     30     57GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0042808; F:neuronal Cdc2-like kinase binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0007420; P:brain development; IMP:UniProtKB.::GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007059; P:chromosome segregation; ISS:UniProtKB.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:UniProtKB.::GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0046600; P:negative regulation of centriole replication; IMP:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0090231; P:regulation of spindle checkpoint; ISS:UniProtKB.
27Q85WU2    2046   YCF1_PINKO Putative protein ycf1 OS=Pinus kor...645     34.3     38     56GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
28Q80YF0    717   MD1L1_CRIGR Mitotic spindle assembly checkpoi...1385     34.3     20     49GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
29Q9WTX8    717   MD1L1_MOUSE Mitotic spindle assembly checkpoi...5716     33.9     21     41GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
30Q74ZC9    294   MED4_ASHGO Mediator of RNA polymerase II tran...1366.7     33.5     26     43GO:0016592; C:mediator complex; IEA:InterPro.
GO:0001104; F:RNA polymerase II transcription cofactor activity; IEA:InterPro.
31O26640    837   RAD50_METTH DNA double-strand break repair Ra...1657.4     33.9     25     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
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