Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL083W
Length:
804
Number of sequences:
5887
Description:
YGL083W SCY1 SGDID:S000003051, Chr VII from 353058-355472, Genome Release 64-1-1, Verified ORF, "Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q1L5Z8    427   HOG1_TORDE Mitogen-activated protein kinase H...1860.000009     52.8     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
152Q8SWM6    488   CDC5_ENCCU Probable cell cycle serine/threoni...1960.000009     52.8     24     45GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
153A3LN91    385   HOG1_PICST Mitogen-activated protein kinase H...1900.000009     52.4     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
154Q8GUH1    834   PUB33_ARATH U-box domain-containing protein 3...2220.00001     52.8     27     42GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
GO:0006950; P:response to stress; IEA:InterPro.
155Q0D4B2    525   CIPKL_ORYSJ CBL-interacting protein kinase 21...2110.00001     52.8     22     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
156P43293    389   NAK_ARATH Probable serine/threonine-protein k...2050.00001     52.4     28     44GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
157Q63651    564   RK_RAT Rhodopsin kinase OS=Rattus norvegicus ...1160.00001     52.8     26     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:InterPro.::GO:0050254; F:rhodopsin kinase activity; IDA:RGD.
GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0022400; P:regulation of rhodopsin mediated signaling pathway; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009586; P:rhodopsin mediated phototransduction; TAS:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.
158O49839    426   APK2A_ARATH Protein kinase 2A, chloroplastic ...2270.00001     52.4     23     43GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009536; C:plastid; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
159Q00771    414   KCC1_EMENI Calcium/calmodulin-dependent prote...2200.00001     52     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
160Q750A9    447   HOG1_ASHGO Mitogen-activated protein kinase H...1860.00001     52     27     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
161O15530    556   PDPK1_HUMAN 3-phosphoinositide-dependent prot...2060.00001     52.4     23     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
162Q15746    1914   MYLK_HUMAN Myosin light chain kinase, smooth ...2370.00001     52.8     20     43GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IDA:UniProtKB.
GO:0060414; P:aorta smooth muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0032060; P:bleb assembly; IMP:UniProtKB.::GO:0071476; P:cellular hypotonic response; IDA:UniProtKB.::GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0090303; P:positive regulation of wound healing; IDA:UniProtKB.::GO:0014820; P:tonic smooth muscle contraction; ISS:UniProtKB.
163Q6FIU2    447   HOG1_CANGA Mitogen-activated protein kinase H...1860.00001     52     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
164O14299    1401   WIS4_SCHPO MAP kinase kinase kinase wis4 OS=S...1810.00002     52.4     26     45GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; NAS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0051403; P:stress-activated MAPK cascade; NAS:PomBase.
165Q9C8M9    719   SRF6_ARATH Protein STRUBBELIG-RECEPTOR FAMILY...1830.00002     52     27     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
166Q7M6U3    1450   TEX14_MOUSE Inactive serine/threonine-protein...1750.00002     52.4     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045171; C:intercellular bridge; IDA:UniProtKB.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0030496; C:midbody; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0008608; P:attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0043063; P:intercellular bridge organization; IDA:UniProtKB.::GO:0007140; P:male meiosis; IMP:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.::GO:0051306; P:mitotic sister chromatid separation; IMP:UniProtKB.::GO:0032466; P:negative regulation of cytokinesis; IDA:MGI.::GO:0032091; P:negative regulation of protein binding; IDA:MGI.
167P21709    976   EPHA1_HUMAN Ephrin type-A receptor 1 OS=Homo ...1910.00002     52.4     27     48GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005005; F:transmembrane-ephrin receptor activity; IDA:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; IDA:UniProtKB.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IDA:UniProtKB.
168Q2RBF0    434   CIPKF_ORYSJ CBL-interacting protein kinase 15...2260.00002     51.6     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
169O65554    441   CIPK6_ARATH CBL-interacting serine/threonine-...2540.00002     51.6     21     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0042538; P:hyperosmotic salinity response; IDA:TAIR.::GO:0007275; P:multicellular organismal development; IMP:TAIR.::GO:0009414; P:response to water deprivation; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.
170Q8C0X8    640   SMKX_MOUSE Sperm motility kinase X OS=Mus mus...1870.00002     52     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
171P29294    1147   MYLK_RABIT Myosin light chain kinase, smooth ...2250.00002     52     20     43GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
172O70293    576   GRK6_MOUSE G protein-coupled receptor kinase ...1800.00002     51.6     23     44GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IEA:EC.
GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
173P97711    576   GRK6_RAT G protein-coupled receptor kinase 6 ...1800.00002     51.6     25     43GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IDA:RGD.
GO:0002029; P:desensitization of G-protein coupled receptor protein signaling pathway; IDA:RGD.::GO:0010360; P:negative regulation of anion channel activity; IMP:RGD.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
174Q0CIC7    370   MPKC_ASPTN Mitogen-activated protein kinase m...1860.00002     51.2     26     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
175Q9WTK7    436   STK11_MOUSE Serine/threonine-protein kinase S...1780.00002     51.2     25     43GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030275; F:LRR domain binding; IPI:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030010; P:establishment of cell polarity; IMP:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:0060770; P:negative regulation of epithelial cell proliferation involved in prostate gland development; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IGI:MGI.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:MGI.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:MGI.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0007286; P:spermatid development; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI.::GO:0001944; P:vasculature development; IMP:UniProtKB.
176Q8SRF5    265   Y823_ENCCU Probable cell division protein kin...2360.00002     50.4     24     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
177Q15831    433   STK11_HUMAN Serine/threonine-protein kinase S...1780.00002     51.2     25     42GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0030295; F:protein kinase activator activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0043276; P:anoikis; IMP:BHF-UCL.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042304; P:regulation of fatty acid biosynthetic process; TAS:Reactome.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0001944; P:vasculature development; ISS:UniProtKB.
178Q3TZA2    342   CDKL4_MOUSE Cyclin-dependent kinase-like 4 OS...1820.00002     50.8     25     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
179Q2QYM3    439   CIPKE_ORYSJ CBL-interacting protein kinase 14...2260.00003     51.2     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
180O88445    282   AURKC_MOUSE Aurora kinase C OS=Mus musculus (...1880.00003     50.4     25     43GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
181Q6PDN3    1941   MYLK_MOUSE Myosin light chain kinase, smooth ...2480.00003     51.6     19     42GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0014820; P:tonic smooth muscle contraction; IMP:UniProtKB.
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