UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL073W

Length:

833

Number of sequences:

5887

Description:

YGL073W HSF1 SGDID:S000003041, Chr VII from 368753-371254, Genome Release 64-1-1, Verified ORF, "Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P10961	833	HSF_YEAST Heat shock factor protein OS=Saccha...	833	0	1686	100	100	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:SGD.
									GO:0032007; P:negative regulation of TOR signaling cascade; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0009408; P:response to heat; IMP:SGD.::GO:0030474; P:spindle pole body duplication; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2	P22121	677	HSF_KLULA Heat shock factor protein OS=1267 /...	399	2e-73	259	40	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3	Q02953	609	HSF_SCHPO Heat shock factor protein OS=Schizo...	237	8e-38	153	37	52	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:PomBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0033554; P:cellular response to stress; IDA:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4	P38530	564	HSF2_CHICK Heat shock factor protein 2 OS=Gal...	232	1e-32	137	32	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5	P38532	525	HSF1_MOUSE Heat shock factor protein 1 OS=Mus...	232	9e-32	134	31	50	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0043234; C:protein complex; IPI:MGI.
									GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:MGI.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.::GO:0009408; P:response to heat; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0007283; P:spermatogenesis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6	P41154	451	HSF_XENLA Heat shock factor protein OS=Xenopu...	232	2e-31	132	31	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7	Q00613	529	HSF1_HUMAN Heat shock factor protein 1 OS=Hom...	232	2e-31	132	31	50	GO:0005737; C:cytoplasm; IDA:HPA.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8	Q08DJ8	525	HSF1_BOVIN Heat shock factor protein 1 OS=Bos...	232	4e-31	132	31	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9	P38529	491	HSF1_CHICK Heat shock factor protein 1 OS=Gal...	231	4e-30	129	31	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10	P38533	535	HSF2_MOUSE Heat shock factor protein 2 OS=Mus...	232	6e-30	129	31	50	GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
									GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11	Q03933	536	HSF2_HUMAN Heat shock factor protein 2 OS=Hom...	232	2e-29	127	30	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
12	Q9R0L1	492	HSF4_MOUSE Heat shock factor protein 4 OS=Mus...	228	3e-29	126	29	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0048468; P:cell development; IMP:MGI.::GO:0033169; P:histone H3-K9 demethylation; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0045597; P:positive regulation of cell differentiation; IMP:MGI.::GO:0008284; P:positive regulation of cell proliferation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0070207; P:protein homotrimerization; IDA:MGI.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13	Q9ULV5	492	HSF4_HUMAN Heat shock factor protein 4 OS=Hom...	228	3e-29	126	30	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14	Q1HGE8	492	HSF4_CANFA Heat shock factor protein 4 OS=Can...	59	0.17	38.9	27	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15	P22813	691	HSF_DROME Heat shock factor protein OS=Drosop...	232	3e-24	112	30	50	GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005700; C:polytene chromosome; IDA:FlyBase.
									GO:0005515; F:protein binding; IPI:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:FlyBase.
									GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0009408; P:response to heat; IDA:FlyBase.::GO:0031427; P:response to methotrexate; IEP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16	P22335	301	HSF24_SOLPE Heat shock factor protein HSF24 O...	147	1e-22	103	37	57	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
17	O81821	481	HFA1B_ARATH Heat stress transcription factor ...	108	2e-21	102	44	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:TAIR.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IMP:TAIR.
									GO:0009408; P:response to heat; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18	Q9SCW4	299	HFB2A_ARATH Heat stress transcription factor ...	202	5e-21	99	32	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0010200; P:response to chitin; IEP:TAIR.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19	Q94J16	440	HFA4B_ORYSJ Heat stress transcription factor ...	119	6e-21	100	40	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20	Q84T61	506	HSFA1_ORYSJ Heat stress transcription factor ...	109	6e-21	100	43	61	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21	Q9SCW5	468	HFA1E_ARATH Heat stress transcription factor ...	106	8e-21	100	43	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22	Q9LQM7	485	HFA1D_ARATH Heat stress transcription factor ...	237	1e-20	99.8	30	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:TAIR.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0009408; P:response to heat; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23	Q6F388	357	HFA2E_ORYSJ Heat stress transcription factor ...	259	2e-20	97.8	29	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
24	Q40152	527	HSF8_SOLLC Heat shock factor protein HSF8 OS=...	119	4e-20	98.6	41	59	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
25	P38531	467	HSF3_CHICK Heat shock factor protein 3 OS=Gal...	113	0.0004	47.8	26	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26	Q9S7U5	374	HSFA8_ARATH Heat stress transcription factor ...	111	7e-20	95.9	40	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27	Q942D6	250	HFC1B_ORYSJ Heat stress transcription factor ...	102	1e-19	94	42	62	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28	Q7XRX3	305	HFB2A_ORYSJ Heat stress transcription factor ...	104	1e-19	94.4	43	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29	Q96320	284	HSFB1_ARATH Heat stress transcription factor ...	110	2e-19	93.6	42	63	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30	P41153	527	HSF8_SOLPE Heat shock factor protein HSF8 OS=...	102	2e-19	96.3	44	64	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31	Q9T0D3	377	HFB2B_ARATH Heat stress transcription factor ...	112	2e-19	94.4	45	59	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
									GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.

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