Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL062W
Length:
1178
Number of sequences:
5887
Description:
YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
841P22102    1010   PUR2_HUMAN Trifunctional purine biosynthetic ...1261.3     37     25     38GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.::GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IEA:EC.::GO:0004644; F:phosphoribosylglycinamide formyltransferase activity; TAS:ProtInc.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.
842Q3SHE7    511   LEU1_THIDA 2-isopropylmalate synthase OS=Thio...1041.4     36.6     21     46
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
843Q9WZ22    538   LY41_THEMA Uncharacterized AIPM/Hcit synthase...1131.4     36.6     23     44
GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
844P48575    531   LEU1_NOSS1 2-isopropylmalate synthase OS=Nost...1001.4     36.6     21     44
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
845B9DMJ6    510   LEU1_STACT 2-isopropylmalate synthase OS=Stap...891.4     36.6     27     51
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
846Q9Z701    809   MUDD_CHLPN Bifunctional enzyme MurC/Ddl OS=Ch...2151.4     37     20     41GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008763; F:UDP-N-acetylmuramate-L-alanine ligase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
847C1DN55    350   HOA3_AZOVD 4-hydroxy-2-oxovalerate aldolase 3...961.4     36.2     28     45
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
848B8E2W9    503   LEU1_DICTD 2-isopropylmalate synthase OS=Dict...1201.4     36.6     24     47
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
849Q9FDL5    417   PUR2_ZYMMO Phosphoribosylamine--glycine ligas...1431.5     36.6     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
850B8DM91    514   LEU1_DESVM 2-isopropylmalate synthase OS=Desu...1521.5     36.6     22     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
851P48570    428   HOSC_YEAST Homocitrate synthase, cytosolic is...751.5     36.6     28     49GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004410; F:homocitrate synthase activity; IDA:SGD.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IGI:SGD.
852B8G187    333   HOA_DESHD 4-hydroxy-2-oxovalerate aldolase OS...2811.5     36.2     22     43
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
853Q44290    377   NIFV1_NOSS1 Homocitrate synthase 1 OS=Nostoc ...1201.6     36.2     23     44
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
854B6JB87    519   LEU1_OLICO 2-isopropylmalate synthase OS=Olig...1131.6     36.6     23     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
855Q8CT26    413   PUR2_STAES Phosphoribosylamine--glycine ligas...1141.6     36.2     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
856Q5HQ96    413   PUR2_STAEQ Phosphoribosylamine--glycine ligas...1141.6     36.2     25     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
857A2BRG6    391   PURT_PROMS Phosphoribosylglycinamide formyltr...1911.6     36.2     21     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
858B3R259    401   PURT_CUPTR Phosphoribosylglycinamide formyltr...2981.7     36.2     20     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
859C4XPA8    513   LEU1_DESMR 2-isopropylmalate synthase OS=Desu...1171.7     36.2     26     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
860Q9HUV8    429   PUR2_PSEAE Phosphoribosylamine--glycine ligas...1471.7     36.2     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
861Q8TJJ1    483   CIMA_METAC Putative (R)-citramalate synthase ...781.7     36.2     35     46
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
862B0BQ46    393   PURT_ACTPJ Phosphoribosylglycinamide formyltr...2101.7     36.2     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
863B5YEF4    503   LEU1_DICT6 2-isopropylmalate synthase OS=Dict...1201.7     36.2     26     46
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
864P48576    533   LEU1_SYNY3 2-isopropylmalate synthase OS=Syne...1001.7     36.2     24     42
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
865Q9CCH9    71   BTB7_MYCLE Biotinylated protein TB7.3 homolog...641.8     33.5     33     59
866B0TCR1    512   LEU1_HELMI 2-isopropylmalate synthase OS=Heli...1481.8     36.2     25     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
867Q0IBI3    540   LEU1_SYNS3 2-isopropylmalate synthase OS=Syne...1001.8     36.2     22     42
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
868P15640    429   PUR2_ECOLI Phosphoribosylamine--glycine ligas...1141.9     36.2     29     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IDA:EcoCyc.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
869B7VIF2    515   LEU1_VIBSL 2-isopropylmalate synthase OS=Vibr...851.9     36.2     28     45
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
870A0RBL2    506   LEU1_BACAH 2-isopropylmalate synthase OS=Baci...1391.9     36.2     25     39
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
871A5EP79    523   LEU1_BRASB 2-isopropylmalate synthase OS=Brad...921.9     36.2     26     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
records
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