Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL062W
Length:
1178
Number of sequences:
5887
Description:
YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
811Q59098    553   ODP2_CUPNH Dihydrolipoyllysine-residue acetyl...590.97     37.4     36     53GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
812P57829    429   PUR2_PASMU Phosphoribosylamine--glycine ligas...1140.99     37     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
813A5IJM2    513   LEU1_THEP1 2-isopropylmalate synthase OS=Ther...1150.99     37     25     43
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
814Q7ME85    331   DDL_VIBVY D-alanine--D-alanine ligase OS=Vibr...2321     37     22     41GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
815Q8EN67    515   LEU1_OCEIH 2-isopropylmalate synthase OS=HTE8...841     37     25     46
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
816Q1LMC7    400   PURT_RALME Phosphoribosylglycinamide formyltr...2981     37     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
817O29108    470   PUR2_ARCFU Phosphoribosylamine--glycine ligas...1711     37     29     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
818Q9UY71    438   PUR2_PYRAB Phosphoribosylamine--glycine ligas...1131     37     26     46
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0000287; F:magnesium ion binding; IEA:HAMAP.::GO:0030145; F:manganese ion binding; IEA:HAMAP.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:HAMAP.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:HAMAP.
819Q87VR8    431   PUR2_PSESM Phosphoribosylamine--glycine ligas...1081.1     37     30     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
820P71559    387   SUCC_MYCTU Succinyl-CoA ligase [ADP-forming] ...491.1     37     45     55GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005829; C:cytosol; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
821A5U0Z1    387   SUCC_MYCTA Succinyl-CoA ligase [ADP-forming] ...491.1     37     45     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
822Q8ZAR2    428   PUR2_YERPE Phosphoribosylamine--glycine ligas...1141.1     37     29     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
823C1ALT7    387   SUCC_MYCBT Succinyl-CoA ligase [ADP-forming] ...491.1     37     45     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
824A1KH85    387   SUCC_MYCBP Succinyl-CoA ligase [ADP-forming] ...491.1     37     45     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
825Q7U0Z1    387   SUCC_MYCBO Succinyl-CoA ligase [ADP-forming] ...491.1     37     45     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:EC.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
826Q4L7U0    510   LEU1_STAHJ 2-isopropylmalate synthase OS=Stap...1661.1     37     27     41
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
827Q2SZW6    404   PURT_BURTA Phosphoribosylglycinamide formyltr...1111.1     37     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
828Q12122    440   HOSM_YEAST Homocitrate synthase, mitochondria...751.1     37     28     49GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004410; F:homocitrate synthase activity; IEA:EC.
GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IMP:SGD.
829Q3MBA3    531   LEU1_ANAVT 2-isopropylmalate synthase OS=Anab...1001.1     37     21     44
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
830Q2KUD7    405   PURT_BORA1 Phosphoribosylglycinamide formyltr...1081.1     37     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
831Q8D2R3    392   PURT_WIGBR Phosphoribosylglycinamide formyltr...1471.2     36.6     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
832Q9CQB2    160   F195A_MOUSE Protein FAM195A OS=Mus musculus (...1301.2     35.4     25     38
GO:0005515; F:protein binding; IPI:MGI.
833Q0I600    389   PURT_SYNS3 Phosphoribosylglycinamide formyltr...2631.2     36.6     22     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
834P10802    638   ODP2_AZOVI Dihydrolipoyllysine-residue acetyl...611.2     37     36     54GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
835A6VIB2    388   PURT_METM7 Phosphoribosylglycinamide formyltr...1601.2     36.6     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
836C5D5M0    515   LEU1_GEOSW 2-isopropylmalate synthase OS=Geob...1261.2     37     23     42
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
837A1VFP6    393   PURT_DESVV Phosphoribosylglycinamide formyltr...1091.3     36.6     30     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
838Q72E56    393   PURT_DESVH Phosphoribosylglycinamide formyltr...1091.3     36.6     30     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
839O19918    152   BCCP_CYACA Biotin carboxyl carrier protein of...851.3     35.4     27     52GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.::GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
840A8M6W8    348   HOA2_SALAI 4-hydroxy-2-oxovalerate aldolase 2...1651.3     36.6     25     42
GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
841P22102    1010   PUR2_HUMAN Trifunctional purine biosynthetic ...1261.3     37     25     38GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.::GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IEA:EC.::GO:0004644; F:phosphoribosylglycinamide formyltransferase activity; TAS:ProtInc.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.::GO:0009113; P:purine base biosynthetic process; IEA:InterPro.
records
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