UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL062W

Length:

1178

Number of sequences:

5887

Description:

YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
781	Q8D781	331	DDL_VIBVU D-alanine--D-alanine ligase OS=Vibr...	233	0.62	37.4	22	42	GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
782	C3LR32	516	LEU1_VIBCM 2-isopropylmalate synthase OS=Vibr...	85	0.63	37.7	29	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
783	Q9KP83	516	LEU1_VIBCH 2-isopropylmalate synthase OS=Vibr...	85	0.63	37.7	29	46
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
784	Q06881	182	BCCP_NOSS1 Biotin carboxyl carrier protein of...	65	0.65	36.6	37	57	GO:0009317; C:acetyl-CoA carboxylase complex; IEA:InterPro.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
785	B4SI67	528	LEU1_STRM5 2-isopropylmalate synthase OS=Sten...	91	0.65	37.7	24	42
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
786	A4J5G8	312	DDL_DESRM D-alanine--D-alanine ligase OS=Desu...	156	0.68	37.4	24	44	GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
787	A1TE53	400	PURT_MYCVP Phosphoribosylglycinamide formyltr...	211	0.68	37.4	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
788	A1K4Y1	393	PURT_AZOSB Phosphoribosylglycinamide formyltr...	102	0.71	37.4	30	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
789	Q0I203	393	PURT_HAES1 Phosphoribosylglycinamide formyltr...	223	0.72	37.4	22	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
790	A2BX52	546	LEU1_PROM5 2-isopropylmalate synthase OS=Proc...	100	0.72	37.7	25	43
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
791	Q9JUK6	517	LEU1_NEIMA 2-isopropylmalate synthase OS=Neis...	122	0.74	37.7	22	42
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
792	Q92AP4	420	PUR2_LISIN Phosphoribosylamine--glycine ligas...	176	0.74	37.4	26	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
									GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
793	B0USF6	517	LEU1_HAES2 2-isopropylmalate synthase OS=Haem...	296	0.74	37.4	21	38
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
794	A1KTV6	517	LEU1_NEIMF 2-isopropylmalate synthase OS=FAM1...	122	0.76	37.4	22	42
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
795	Q9FN52	503	MAM3_ARATH Methylthioalkylmalate synthase 3, ...	137	0.77	37.4	22	44	GO:0009507; C:chloroplast; IDA:TAIR.
									GO:0010177; F:2-(2'-methylthio)ethylmalate synthase activity; IDA:TAIR.::GO:0003852; F:2-isopropylmalate synthase activity; NAS:TAIR.
									GO:0019761; P:glucosinolate biosynthetic process; IDA:TAIR.::GO:0009098; P:leucine biosynthetic process; TAS:TAIR.
796	Q39QR8	392	PURT_GEOMG Phosphoribosylglycinamide formyltr...	304	0.77	37.4	22	38
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
797	Q12SE7	522	LEU1_SHEDO 2-isopropylmalate synthase OS=Shew...	147	0.78	37.4	27	44
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
798	Q2N8K3	390	PURT_ERYLH Phosphoribosylglycinamide formyltr...	252	0.79	37.4	23	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
799	Q5WQ01	516	LEU1_BUCCC 2-isopropylmalate synthase OS=Buch...	282	0.79	37.4	21	41
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
800	Q7V121	546	LEU1_PROMP 2-isopropylmalate synthase OS=Proc...	100	0.81	37.4	25	43
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
801	Q6D796	343	HOA_ERWCT 4-hydroxy-2-oxovalerate aldolase OS...	173	0.82	37	25	40
									GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
802	Q8TKQ6	405	AKSA_METAC Putative homocitrate synthase AksA...	80	0.83	37.4	26	44
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
803	A2SQ86	430	PUR2_METLZ Phosphoribosylamine--glycine ligas...	139	0.84	37.4	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
									GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
804	Q9Y823	418	HOSM_SCHPO Homocitrate synthase, mitochondria...	95	0.86	37.4	31	47	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005739; C:mitochondrion; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
									GO:0004410; F:homocitrate synthase activity; IMP:PomBase.
									GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0019878; P:lysine biosynthetic process via aminoadipic acid; IMP:PomBase.
805	Q87Q53	391	PURT_VIBPA Phosphoribosylglycinamide formyltr...	211	0.91	37	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
806	B1L8U2	513	LEU1_THESQ 2-isopropylmalate synthase OS=Ther...	83	0.92	37.4	28	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
807	Q9WZ23	513	LEU1_THEMA 2-isopropylmalate synthase OS=Ther...	83	0.92	37.4	28	47
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
808	A4YZ76	525	LEU1_BRASO 2-isopropylmalate synthase OS=Brad...	92	0.95	37.4	26	40
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
809	Q2T7S9	347	HOA_BURTA 4-hydroxy-2-oxovalerate aldolase OS...	161	0.97	37	26	42
									GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
810	Q479E5	354	HOA5_DECAR 4-hydroxy-2-oxovalerate aldolase 5...	96	0.97	37	28	45
									GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
811	Q59098	553	ODP2_CUPNH Dihydrolipoyllysine-residue acetyl...	59	0.97	37.4	36	53	GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.

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