UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL062W

Length:

1178

Number of sequences:

5887

Description:

YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	A6ZMR9	2273	HFA1_YEAS7 Acetyl-CoA carboxylase, mitochondr...	75	2.5	36.2	29	51	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
62	P11497	2345	ACACA_RAT Acetyl-CoA carboxylase 1 OS=Rattus ...	496	7e-61	233	32	50	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0003989; F:acetyl-CoA carboxylase activity; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0019900; F:kinase binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006084; P:acetyl-CoA metabolic process; IDA:RGD.::GO:0006633; P:fatty acid biosynthetic process; IDA:RGD.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IMP:RGD.
63	C8ZF72	2273	HFA1_YEAS8 Acetyl-CoA carboxylase, mitochondr...	75	2.3	36.2	29	51	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
64	P32874	2273	HFA1_YEAST Acetyl-CoA carboxylase, mitochondr...	75	2.6	36.2	29	51	GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0003989; F:acetyl-CoA carboxylase activity; IGI:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IGI:SGD.
65	C7GRE4	2273	HFA1_YEAS2 Acetyl-CoA carboxylase, mitochondr...	75	2.7	36.2	29	51	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
66	B3LM95	2273	HFA1_YEAS1 Acetyl-CoA carboxylase, mitochondr...	75	2.7	36.2	29	51	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
67	Q54J08	2282	ACAC_DICDI Acetyl-CoA carboxylase OS=Dictyost...	55	4.4	35.4	36	49	GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005789; C:endoplasmic reticulum membrane; ISS:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005739; C:mitochondrion; ISS:dictyBase.
									GO:0003989; F:acetyl-CoA carboxylase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; ISS:dictyBase.::GO:0006998; P:nuclear envelope organization; ISS:dictyBase.::GO:0006606; P:protein import into nucleus; ISS:dictyBase.
68	Q00955	2233	ACAC_YEAST Acetyl-CoA carboxylase OS=Saccharo...	101	0.023	42.7	29	49	GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0003989; F:acetyl-CoA carboxylase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IMP:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0006998; P:nuclear envelope organization; TAS:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.
69	O00763	2458	ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo ...	514	9e-60	229	31	49	GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
									GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006853; P:carnitine shuttle; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0046320; P:regulation of fatty acid oxidation; TAS:Reactome.
70	P78820	2280	ACAC_SCHPO Acetyl-CoA carboxylase OS=Schizosa...	71	0.36	38.9	32	52	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.
									GO:0003989; F:acetyl-CoA carboxylase activity; ISS:PomBase.::GO:0005524; F:ATP binding; ISS:PomBase.::GO:0004075; F:biotin carboxylase activity; ISS:PomBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0042759; P:long-chain fatty acid biosynthetic process; IMP:PomBase.::GO:0007088; P:regulation of mitosis; IMP:PomBase.
71	Q8S6N5	2267	ACC1_ORYSJ Acetyl-CoA carboxylase 1 OS=Oryza ...	538	4e-59	227	29	47	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
72	B9FK36	2327	ACC2_ORYSJ Acetyl-CoA carboxylase 2 OS=Oryza ...	80	6.4	34.7	30	49	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
73	F4I1L3	2355	ACC2_ARATH Acetyl-CoA carboxylase 2 OS=Arabid...	556	9e-58	223	29	47	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
74	Q38970	2254	ACC1_ARATH Acetyl-CoA carboxylase 1 OS=Arabid...	539	9e-58	223	30	47	GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0030497; P:fatty acid elongation; IMP:TAIR.::GO:0010072; P:primary shoot apical meristem specification; IMP:TAIR.::GO:0009735; P:response to cytokinin stimulus; IMP:TAIR.::GO:0048364; P:root development; IMP:TAIR.
75	Q97FT3	1065	CARB_CLOAB Carbamoyl-phosphate synthase large...	330	0.00000000004	71.2	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
76	A2BJL3	1073	CARB_HYPBU Carbamoyl-phosphate synthase large...	226	0.004	45.1	20	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
77	Q1WVA9	1061	CARB_LACS1 Carbamoyl-phosphate synthase large...	188	0.0007	47.8	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
78	Q03HB0	1057	CARB_PEDPA Carbamoyl-phosphate synthase large...	353	0.000000007	63.9	22	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
79	Q8U085	1056	CARB_PYRFU Carbamoyl-phosphate synthase large...	224	0.003	45.4	20	39
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
80	C4ZEK2	1068	CARB_EUBR3 Carbamoyl-phosphate synthase large...	237	0.00000000008	70.5	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
81	Q67Q54	1084	CARB_SYMTH Carbamoyl-phosphate synthase large...	310	0.00000000005	70.9	22	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
82	Q8Z9L7	1075	CARB_SALTI Carbamoyl-phosphate synthase large...	234	0.000000003	65.5	25	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
83	Q87SF3	1077	CARB_VIBPA Carbamoyl-phosphate synthase large...	242	0.000001	57	23	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
84	P14846	1075	CARB_SALTY Carbamoyl-phosphate synthase large...	234	0.000000003	65.5	25	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
85	Q8ZIL4	1077	CARB_YERPE Carbamoyl-phosphate synthase large...	234	0.00000002	62.8	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
86	Q4J8E8	1052	CARB_SULAC Carbamoyl-phosphate synthase large...	251	0.001	46.6	19	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
87	C1EPQ0	1072	CARB_BACC3 Carbamoyl-phosphate synthase large...	349	0.00000006	60.8	21	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
88	A0RHQ8	1072	CARB_BACAH Carbamoyl-phosphate synthase large...	349	0.00000006	60.8	21	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
89	Q81WF2	1072	CARB_BACAN Carbamoyl-phosphate synthase large...	353	0.00000004	61.6	21	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
90	C3L740	1072	CARB_BACAC Carbamoyl-phosphate synthase large...	353	0.00000004	61.6	21	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
91	C3P656	1072	CARB_BACAA Carbamoyl-phosphate synthase large...	353	0.00000004	61.6	21	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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