UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGL062W

Length:

1178

Number of sequences:

5887

Description:

YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
451	P35915	298	HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase O...	79	0.005	43.9	27	53	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
									GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
452	B8I1T7	508	LEU1_CLOCE 2-isopropylmalate synthase OS=H10)...	215	0.005	44.3	20	41
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
453	Q764S0	337	HOA_BACPJ 4-hydroxy-2-oxovalerate aldolase OS...	192	0.005	43.9	26	45
									GO:0008701; F:4-hydroxy-2-oxovalerate aldolase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
454	A4IVS8	386	PURT_FRATW Phosphoribosylglycinamide formyltr...	300	0.005	44.3	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
455	Q1I5Y3	393	PURT_PSEE4 Phosphoribosylglycinamide formyltr...	194	0.006	44.3	25	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
456	A0R2Y2	400	PURT_MYCS2 Phosphoribosylglycinamide formyltr...	211	0.006	43.9	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
457	Q0AGN5	510	LEU1_NITEC 2-isopropylmalate synthase OS=Nitr...	88	0.006	44.3	30	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
458	Q0BP50	386	PURT_FRATO Phosphoribosylglycinamide formyltr...	300	0.006	43.9	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
459	Q2A5V8	386	PURT_FRATH Phosphoribosylglycinamide formyltr...	300	0.006	43.9	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
460	A7N9C6	386	PURT_FRATF Phosphoribosylglycinamide formyltr...	300	0.006	43.9	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
461	Q3A5Q4	393	PURT_PELCD Phosphoribosylglycinamide formyltr...	332	0.007	43.9	22	38
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
462	Q8RC54	417	PUR2_THETN Phosphoribosylamine--glycine ligas...	94	0.007	43.9	32	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
									GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
463	Q8UDE9	1162	CARB_AGRT5 Carbamoyl-phosphate synthase large...	197	0.011	43.9	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
464	B3DX88	506	LEU1_METI4 2-isopropylmalate synthase OS=(str...	167	0.007	43.9	25	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
465	P05342	385	NIFV_AZOVI Homocitrate synthase OS=Azotobacte...	135	0.007	43.9	22	44
									GO:0004410; F:homocitrate synthase activity; IEA:EC.
									GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.::GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
466	Q3BW63	400	PURT_XANC5 Phosphoribosylglycinamide formyltr...	117	0.008	43.9	30	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
467	Q056L2	387	PURT_LEPBL Phosphoribosylglycinamide formyltr...	299	0.008	43.9	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
468	Q04P21	387	PURT_LEPBJ Phosphoribosylglycinamide formyltr...	299	0.008	43.9	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
469	A1RMT4	391	PURT_SHESW Phosphoribosylglycinamide formyltr...	196	0.008	43.9	27	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
470	B2VDA7	522	LEU1_ERWT9 2-isopropylmalate synthase OS=Erwi...	126	0.008	43.9	24	44
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
471	Q5NE84	386	PURT_FRATT Phosphoribosylglycinamide formyltr...	300	0.008	43.5	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
472	Q14FN7	386	PURT_FRAT1 Phosphoribosylglycinamide formyltr...	300	0.008	43.5	24	41
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
473	A5F083	329	DDL_VIBC3 D-alanine--D-alanine ligase OS=Vibr...	267	0.008	43.5	22	41	GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
474	A6LHW2	393	PURT_PARD8 Phosphoribosylglycinamide formyltr...	305	0.008	43.5	25	37
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
475	Q64UB2	388	PURT_BACFR Phosphoribosylglycinamide formyltr...	370	0.009	43.5	22	40
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
476	Q5SH23	280	LYSX_THET8 Alpha-aminoadipate--LysW ligase Ly...	108	0.009	43.1	31	48
									GO:0016881; F:acid-amino acid ligase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0009085; P:lysine biosynthetic process; IEA:UniProtKB-KW.::GO:0006464; P:protein modification process; IEA:InterPro.
477	B1I3W6	306	DDL_DESAP D-alanine--D-alanine ligase OS=Desu...	216	0.009	43.1	22	40	GO:0005618; C:cell wall; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008716; F:D-alanine-D-alanine ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
478	Q5E4R4	391	PURT_VIBF1 Phosphoribosylglycinamide formyltr...	307	0.009	43.5	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
									GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
479	A9KY13	522	LEU1_SHEB9 2-isopropylmalate synthase OS=Shew...	284	0.009	43.9	24	39
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
480	Q974X3	386	LEU1_SULTO Probable 2-isopropylmalate synthas...	108	0.009	43.5	25	45
									GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
									GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
481	Q8UHN3	423	PUR2_AGRT5 Phosphoribosylamine--glycine ligas...	145	0.009	43.5	30	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004637; F:phosphoribosylamine-glycine ligase activity; IEA:EC.
									GO:0009113; P:purine base biosynthetic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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