Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL062W
Length:
1178
Number of sequences:
5887
Description:
YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q8NX94    374   PURK_STAAW N5-carboxyaminoimidazole ribonucle...2210.0001     49.3     23     40
GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
362Q6GAE8    374   PURK_STAAS N5-carboxyaminoimidazole ribonucle...2210.0001     49.3     23     40
GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
363A1SRG8    519   LEU1_PSYIN 2-isopropylmalate synthase OS=Psyc...2540.0001     49.7     23     40
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
364B8GEA3    1056   CARB_METPE Carbamoyl-phosphate synthase large...2270.028     42.4     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
365Q8TB92    370   HMGC2_HUMAN Probable 3-hydroxymethyl-3-methyl...1150.0001     49.3     26     51
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
366A7Z0Z2    384   PURT_BACA2 Phosphoribosylglycinamide formyltr...3380.0002     48.9     22     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
367A2BWY5    390   PURT_PROM5 Phosphoribosylglycinamide formyltr...2150.0002     48.9     25     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
368A8FFW5    517   LEU11_BACP2 2-isopropylmalate synthase 1 OS=B...1040.0002     49.3     24     47
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
369Q58881    389   PURT_METJA Phosphoribosylglycinamide formyltr...2110.0002     48.9     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
370Q29448    325   HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, ...1220.0002     48.5     25     48GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.
371Q8YIC2    1162   CARB_BRUME Carbamoyl-phosphate synthase large...2500.1     40.8     20     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
372P13258    398   CARB_METBA Carbamoyl-phosphate synthase large...2550.0002     48.5     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
373Q8FZJ3    1162   CARB_BRUSU Carbamoyl-phosphate synthase large...2610.087     40.8     20     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
374Q2LWJ3    516   LEU1_SYNAS 2-isopropylmalate synthase OS=Synt...1170.0003     48.5     29     44
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
375A4J181    505   LEU1_DESRM 2-isopropylmalate synthase OS=Desu...1630.0003     48.5     28     44
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
376Q8XXP1    513   LEU11_RALSO 2-isopropylmalate synthase 1 OS=R...1270.0003     48.5     25     46
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
377Q8PN36    400   PURT_XANAC Phosphoribosylglycinamide formyltr...1950.0003     48.1     26     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
378Q8RCF9    384   LEU12_THETN 2-isopropylmalate synthase 2 OS=1...2100.0003     48.1     24     43
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.::GO:0004410; F:homocitrate synthase activity; IEA:InterPro.
GO:0051188; P:cofactor biosynthetic process; IEA:InterPro.::GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
379O34873    299   HMGCL_BACSU Hydroxymethylglutaryl-CoA lyase y...930.0003     47.8     27     48
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
380O66682    528   LY41_AQUAE Uncharacterized AIPM/Hcit synthase...1400.0003     48.5     24     47
GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
381O27525    505   LEU1_METTH Probable 2-isopropylmalate synthas...1770.0004     48.1     26     42
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
382C6BV99    393   PURT_DESAD Phosphoribosylglycinamide formyltr...2220.0004     47.8     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
383Q2FLD9    1056   CARB_METHJ Carbamoyl-phosphate synthase large...2230.026     42.4     20     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
384Q9HK17    1047   CARB_THEAC Carbamoyl-phosphate synthase large...2910.0004     48.5     23     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
385A6WCC6    1104   CARB_KINRD Carbamoyl-phosphate synthase large...2380.0008     47.4     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
386Q31DQ3    393   PURT_THICR Phosphoribosylglycinamide formyltr...3050.0004     47.8     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
387Q98I87    1167   CARB_RHILO Carbamoyl-phosphate synthase large...1900.001     47     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
388Q971S5    460   HOSA_SULTO Putative homocitrate synthase OS=S...890.0005     47.8     26     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
389Q5R9E1    325   HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, ...1220.0005     47.4     25     47GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
390Q8HXZ6    325   HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, ...2090.0005     47.4     25     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; ISS:UniProtKB.
391C3NDV7    461   HOSA_SULIY Putative homocitrate synthase OS=S...1510.0006     47.8     23     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0004410; F:homocitrate synthase activity; IEA:EC.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
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