Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL062W
Length:
1178
Number of sequences:
5887
Description:
YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P46392    598   BCCA_MYCLE Acetyl-/propionyl-coenzyme A carbo...630.057     41.2     35     54
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
32Q54KE6    699   MCCA_DICDI Methylcrotonoyl-CoA carboxylase su...640.00001     53.1     41     64GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; ISS:dictyBase.
GO:0006552; P:leucine catabolic process; ISS:dictyBase.
33Q99MR8    717   MCCA_MOUSE Methylcrotonoyl-CoA carboxylase su...670.000003     55.5     42     60GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
34P24182    449   ACCC_ECOLI Biotin carboxylase OS=Escherichia ...4407e-105     344     46     63
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:EcoCyc.
GO:0006633; P:fatty acid biosynthetic process; IMP:EcoCyc.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; IMP:EcoliWiki.
35Q91ZA3    724   PCCA_MOUSE Propionyl-CoA carboxylase alpha ch...670.00002     52.8     40     61GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IMP:MGI.
36Q8X9B6    449   ACCC_ECO57 Biotin carboxylase OS=Escherichia ...4401e-104     343     46     63
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
37P05165    728   PCCA_HUMAN Propionyl-CoA carboxylase alpha ch...650.00002     52.4     42     58GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:ProtInc.
GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.::GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome.
38P0A508    654   BCCA_MYCTU Acetyl-/propionyl-coenzyme A carbo...710.0002     49.3     38     58GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
39P0A509    654   BCCA_MYCBO Acetyl-/propionyl-coenzyme A carbo...710.0002     49.3     38     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
40Q2QMG2    737   MCCA_ORYSJ Methylcrotonoyl-CoA carboxylase su...810.0000003     58.5     36     63GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
41P14882    737   PCCA_RAT Propionyl-CoA carboxylase alpha chai...650.0001     49.7     40     60GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:RGD.
GO:0009063; P:cellular amino acid catabolic process; TAS:RGD.::GO:0009062; P:fatty acid catabolic process; TAS:RGD.
42O52058    449   ACCC_ALLVD Biotin carboxylase OS=(Chromatium ...4395e-101     333     45     60
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
43Q42777    731   MCCA_SOYBN Methylcrotonoyl-CoA carboxylase su...670.0000002     58.9     43     66GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC.
44Q612F5    738   PCCA_CAEBR Propionyl-CoA carboxylase alpha ch...1210.00004     51.6     34     51GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IEA:EC.
45Q19842    724   PCCA_CAEEL Propionyl-CoA carboxylase alpha ch...1860.000006     54.3     30     44GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IEA:EC.
46Q58628    567   PYCB_METJA Pyruvate carboxylase subunit B OS=...6135e-95     321     33     55
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:InterPro.
47P38095    1241   LAMA_EMENI Putative urea carboxylase OS=194 /...934.6     35     27     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IEA:EC.
GO:0006457; P:protein folding; IEA:InterPro.
48D3DJ41    652   2OCL_HYDTT 2-oxoglutarate carboxylase large s...6356e-85     295     31     51
GO:0034029; F:2-oxoglutarate carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
49P13187    596   DCOA_KLEPN Oxaloacetate decarboxylase alpha c...6327e-85     293     32     50
GO:0008948; F:oxaloacetate decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
50P32528    1835   DUR1_YEAST Urea amidolyase OS=Saccharomyces c...510.002     46.6     39     71GO:0005737; C:cytoplasm; IDA:SGD.
GO:0004039; F:allophanate hydrolase activity; IMP:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IMP:SGD.
GO:0000256; P:allantoin catabolic process; TAS:SGD.::GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0043419; P:urea catabolic process; IMP:SGD.
51Q03030    591   DCOA_SALTY Oxaloacetate decarboxylase alpha c...6292e-83     289     32     50
GO:0008948; F:oxaloacetate decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
52O27179    568   PYCB_METTH Pyruvate carboxylase subunit B OS=...6212e-83     288     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:InterPro.
53Q8XGX8    591   DCOA_SALTI Oxaloacetate decarboxylase alpha c...6332e-83     288     32     50
GO:0008948; F:oxaloacetate decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
54A5H0J2    1830   DUR1_LACKL Urea amidolyase OS=Lachancea kluyv...970.02     43.1     26     53
GO:0004039; F:allophanate hydrolase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0016884; F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:InterPro.::GO:0004847; F:urea carboxylase activity; IEA:EC.
GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:InterPro.
55Q70AC7    505   5S_PROFR Methylmalonyl-CoA carboxyltransferas...4584e-63     228     33     54
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0047154; F:methylmalonyl-CoA carboxytransferase activity; IEA:EC.
56Q13085    2346   ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo ...5931e-62     239     31     49GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.
57Q5SWU9    2345   ACACA_MOUSE Acetyl-CoA carboxylase 1 OS=Mus m...4966e-62     236     32     50GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0003989; F:acetyl-CoA carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006084; P:acetyl-CoA metabolic process; IDA:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IDA:UniProtKB.::GO:0055088; P:lipid homeostasis; IMP:MGI.::GO:0044268; P:multicellular organismal protein metabolic process; IMP:MGI.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0001894; P:tissue homeostasis; IMP:MGI.
58Q9TTS3    2346   ACACA_BOVIN Acetyl-CoA carboxylase 1 OS=Bos t...5071e-61     236     32     50GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
59Q28559    2346   ACACA_SHEEP Acetyl-CoA carboxylase 1 OS=Ovis ...4961e-61     235     32     50GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0003989; F:acetyl-CoA carboxylase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006084; P:acetyl-CoA metabolic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.
60P11029    2324   ACAC_CHICK Acetyl-CoA carboxylase OS=Gallus g...5932e-61     235     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
61A6ZMR9    2273   HFA1_YEAS7 Acetyl-CoA carboxylase, mitochondr...752.5     36.2     29     51GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
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