Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL062W
Length:
1178
Number of sequences:
5887
Description:
YGL062W PYC1 SGDID:S000003030, Chr VII from 385196-388732, Genome Release 64-1-1, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q09794    2244   PYR1_SCHPO Protein ura1 OS=Schizosaccharomyce...3420.001     47     18     40GO:0005829; C:cytosol; IDA:PomBase.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IGI:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0004151; F:dihydroorotase activity; IGI:PomBase.::GO:0003922; F:GMP synthase (glutamine-hydrolyzing) activity; IGI:PomBase.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IGI:PomBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000050; P:urea cycle; IC:PomBase.
302Q8TYB1    499   LEU1_METKA Probable 2-isopropylmalate synthas...1770.0000007     57     28     45
GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC.
GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
303P39771    384   PURT_BACSU Phosphoribosylglycinamide formyltr...2950.0000007     56.6     24     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
304Q9A4D6    1099   CARB_CAUCR Carbamoyl-phosphate synthase large...2530.001     46.6     21     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
305P03965    1118   CARB_YEAST Carbamoyl-phosphate synthase argin...1850.043     42     21     42GO:0005951; C:carbamoyl-phosphate synthase complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IMP:SGD.
306Q8C196    1500   CPSM_MOUSE Carbamoyl-phosphate synthase [ammo...3080.00004     52     20     38
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IMP:MGI.
GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0000050; P:urea cycle; IC:MGI.
307P07756    1500   CPSM_RAT Carbamoyl-phosphate synthase [ammoni...3080.00004     52     20     38GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0005509; F:calcium ion binding; IPI:RGD.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IDA:RGD.::GO:0004175; F:endopeptidase activity; IMP:RGD.::GO:0016595; F:glutamate binding; IPI:RGD.::GO:0005543; F:phospholipid binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.
GO:0055081; P:anion homeostasis; IDA:RGD.::GO:0071320; P:cellular response to cAMP; IEP:RGD.::GO:0044344; P:cellular response to fibroblast growth factor stimulus; IEP:RGD.::GO:0071377; P:cellular response to glucagon stimulus; IEP:RGD.::GO:0071400; P:cellular response to oleic acid; IEP:RGD.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0070365; P:hepatocyte differentiation; IEP:RGD.::GO:0007494; P:midgut development; IEP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032094; P:response to food; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0010043; P:response to zinc ion; IEP:RGD.::GO:0000050; P:urea cycle; IDA:RGD.
308C1F1S6    1093   CARB_ACIC5 Carbamoyl-phosphate synthase large...2450.000003     55.5     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
309B8H8U5    1109   CARB_ARTCA Carbamoyl-phosphate synthase large...2390.000002     56.2     24     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
310O67869    557   CARB1_AQUAE Carbamoyl-phosphate synthase larg...2110.000001     55.8     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
311P31327    1500   CPSM_HUMAN Carbamoyl-phosphate synthase [ammo...3080.005     45.1     19     37GO:0042645; C:mitochondrial nucleoid; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004087; F:carbamoyl-phosphate synthase (ammonia) activity; IMP:BHF-UCL.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.
GO:0070409; P:carbamoyl phosphate biosynthetic process; IMP:UniProtKB.::GO:0019240; P:citrulline biosynthetic process; NAS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0005980; P:glycogen catabolic process; IMP:BHF-UCL.::GO:0050667; P:homocysteine metabolic process; IDA:UniProtKB.::GO:0046209; P:nitric oxide metabolic process; IMP:BHF-UCL.::GO:0045909; P:positive regulation of vasodilation; IMP:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IDA:UniProtKB.::GO:0019433; P:triglyceride catabolic process; IMP:BHF-UCL.::GO:0000050; P:urea cycle; NAS:BHF-UCL.
312B0REV9    1096   CARB_CLAMS Carbamoyl-phosphate synthase large...1960.00006     51.2     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
313P02904    123   BCCP_PROFR Methylmalonyl-CoA carboxyltransfer...640.000002     52.8     42     66
GO:0047154; F:methylmalonyl-CoA carboxytransferase activity; IEA:EC.
314A0JX72    1099   CARB_ARTS2 Carbamoyl-phosphate synthase large...1950.00001     53.5     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
315Q8TYM1    509   CIMA_METKA Putative (R)-citramalate synthase ...1240.000002     55.5     31     47
GO:0043714; F:(R)-citramalate synthase activity; IEA:InterPro.::GO:0003852; F:2-isopropylmalate synthase activity; IEA:InterPro.
GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0009098; P:leucine biosynthetic process; IEA:InterPro.
316Q8EYF0    387   PURT_LEPIN Phosphoribosylglycinamide formyltr...3000.000003     54.7     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
317Q72LY0    387   PURT_LEPIC Phosphoribosylglycinamide formyltr...3000.000003     54.7     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
318A9WSA8    1106   CARB_RENSM Carbamoyl-phosphate synthase large...1950.001     47.4     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
319B8DTW3    1136   CARB_BIFA0 Carbamoyl-phosphate synthase large...2610.0008     47.4     22     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
320C4LDC0    394   PURT_TOLAT Phosphoribosylglycinamide formyltr...1840.000004     54.3     30     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016742; F:hydroxymethyl-, formyl- and related transferase activity; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:InterPro.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0009152; P:purine ribonucleotide biosynthetic process; IEA:InterPro.
321A0B8K9    1074   CARB_METTP Carbamoyl-phosphate synthase large...2251.3     37     20     37
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
322P20054    2225   PYR1_DICDI Protein PYR1-3 OS=Dictyostelium di...1880.046     42     22     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:dictyBase.::GO:0004151; F:dihydroorotase activity; IDA:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:dictyBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
323Q9ZAA7    145   GCDC_ACIFV Glutaconyl-CoA decarboxylase subun...680.000005     51.6     40     62
GO:0018801; F:glutaconyl-CoA decarboxylase activity; IEA:EC.
GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
324A5CRX5    1096   CARB_CLAM3 Carbamoyl-phosphate synthase large...1960.0001     50.1     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
325Q8RSS3    1076   CARB_HALER Carbamoyl-phosphate synthase large...3090.00007     50.8     19     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
326P05115    70   BCCP_SOLLC Biotin carboxyl carrier protein of...660.000006     50.4     41     64GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
327A1R6Z3    1102   CARB_ARTAT Carbamoyl-phosphate synthase large...2390.000006     54.7     24     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
328B7GPW2    1127   CARB_BIFLS Carbamoyl-phosphate synthase large...3180.003     45.4     20     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
329P59448    1076   CARB_BUCBP Carbamoyl-phosphate synthase large...2440.00007     50.8     19     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
330B2GI87    1106   CARB_KOCRD Carbamoyl-phosphate synthase large...3490.0002     49.3     21     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW.
331Q49WI9    375   PURK_STAS1 N5-carboxyaminoimidazole ribonucle...2660.000009     53.1     21     39
GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro.
GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
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