rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q9WZ27 | 1099 | CARB_THEMA Carbamoyl-phosphate synthase large... | 307 | 0.0000004 | 58.2 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 242 | P27708 | 2225 | PYR1_HUMAN CAD protein OS=Homo sapiens (Human... | 194 | 2 | 36.6 | 20 | 37 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0043195; C:terminal button; ISS:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; ISS:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.::GO:0005524; F:ATP binding; ISS:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.::GO:0004151; F:dihydroorotase activity; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0017144; P:drug metabolic process; ISS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 243 | C1CXR4 | 1029 | CARB_DEIDV Carbamoyl-phosphate synthase large... | 232 | 0.00006 | 51.2 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 244 | P08955 | 2225 | PYR1_MESAU CAD protein OS=Mesocricetus auratu... | 194 | 0.41 | 38.9 | 21 | 38 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; IDA:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:BHF-UCL.::GO:0004151; F:dihydroorotase activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IDA:BHF-UCL.::GO:0002134; F:UTP binding; IDA:MGI. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 245 | O93937 | 2275 | PYR1_EMENI Protein pyrABCN OS=194 / M139) (As... | 311 | 0.0003 | 48.9 | 19 | 38 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; TAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; TAS:UniProtKB.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 246 | Q7VP67 | 1075 | CARB_HAEDU Carbamoyl-phosphate synthase large... | 238 | 0.000005 | 54.7 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 247 | Q1IPK2 | 1102 | CARB_KORVE Carbamoyl-phosphate synthase large... | 236 | 0.000001 | 56.6 | 22 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 248 | Q469Z7 | 1071 | CARB_METBF Carbamoyl-phosphate synthase large... | 240 | 0.0003 | 48.9 | 24 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 249 | Q87WP4 | 1073 | CARB_PSESM Carbamoyl-phosphate synthase large... | 236 | 0.000001 | 57 | 23 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 250 | Q5HQA5 | 375 | PURK_STAEQ N5-carboxyaminoimidazole ribonucle... | 246 | 0.00000002 | 61.6 | 23 | 42 | | | | | | | | | | | GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro. | | | | | | | | | | GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro. | 251 | A3CNI5 | 1059 | CARB_STRSV Carbamoyl-phosphate synthase large... | 349 | 0.000004 | 55.1 | 21 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 252 | Q58773 | 482 | CARB1_METJA Carbamoyl-phosphate synthase larg... | 235 | 0.00000002 | 62 | 24 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 253 | A6LPD9 | 1069 | CARB_CLOB8 Carbamoyl-phosphate synthase large... | 339 | 0.00000004 | 61.6 | 20 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 254 | B9KB91 | 1099 | CARB_THENN Carbamoyl-phosphate synthase large... | 281 | 0.0000004 | 58.2 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 255 | P05990 | 2224 | PYR1_DROME CAD protein OS=Drosophila melanoga... | 320 | 0.00000002 | 62.4 | 21 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:FlyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:FlyBase.::GO:0004151; F:dihydroorotase activity; IDA:FlyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IMP:FlyBase.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 256 | Q91437 | 2242 | PYR1_SQUAC CAD protein OS=Squalus acanthias (... | 190 | 5.4 | 35 | 19 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 257 | O25577 | 1085 | CARB_HELPY Carbamoyl-phosphate synthase large... | 318 | 0.0000002 | 59.7 | 21 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 258 | Q55756 | 1081 | CARB_SYNY3 Carbamoyl-phosphate synthase large... | 329 | 0.012 | 43.5 | 20 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 259 | P57244 | 1079 | CARB_BUCAI Carbamoyl-phosphate synthase large... | 237 | 0.00000008 | 60.5 | 22 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 260 | A8AB61 | 399 | LEU1_IGNH4 Probable 2-isopropylmalate synthas... | 184 | 0.00000003 | 60.8 | 30 | 46 | | | | | | | | | | | GO:0003852; F:2-isopropylmalate synthase activity; IEA:EC. | | | | | | | | | | GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW. | 261 | B1HQC1 | 1065 | CARB_LYSSC Carbamoyl-phosphate synthase large... | 349 | 0.00000005 | 61.2 | 23 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 262 | B1L8T8 | 1099 | CARB_THESQ Carbamoyl-phosphate synthase large... | 307 | 0.0000005 | 58.2 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 263 | Q1B9F9 | 1112 | CARB_MYCSS Carbamoyl-phosphate synthase large... | 250 | 0.00009 | 50.4 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 264 | A1UFK4 | 1112 | CARB_MYCSK Carbamoyl-phosphate synthase large... | 250 | 0.00009 | 50.4 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 265 | A3PZ65 | 1112 | CARB_MYCSJ Carbamoyl-phosphate synthase large... | 250 | 0.00009 | 50.4 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 266 | B0KBW4 | 1072 | CARB_THEP3 Carbamoyl-phosphate synthase large... | 317 | 0.000002 | 55.8 | 20 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 267 | O28994 | 1076 | CARB_ARCFU Carbamoyl-phosphate synthase large... | 310 | 0.00002 | 53.1 | 22 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 268 | Q9CCR2 | 1121 | CARB_MYCLE Carbamoyl-phosphate synthase large... | 236 | 0.000003 | 55.8 | 23 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 269 | Q8TNY4 | 1070 | CARB_METAC Carbamoyl-phosphate synthase large... | 237 | 0.03 | 42.4 | 21 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 270 | C1A4I5 | 1094 | CARB_GEMAT Carbamoyl-phosphate synthase large... | 195 | 0.0000009 | 57 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 271 | Q8CPP2 | 375 | PURK_STAES N5-carboxyaminoimidazole ribonucle... | 246 | 0.00000005 | 60.1 | 23 | 42 | | | | | | | | | | | GO:0034028; F:5-(carboxyamino)imidazole ribonucleotide synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0004638; F:phosphoribosylaminoimidazole carboxylase activity; IEA:InterPro. | | | | | | | | | | GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro. |