Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL058W
Length:
172
Number of sequences:
5887
Description:
YGL058W RAD6 SGDID:S000003026, Chr VII from 393986-394504, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (as a heterodimer with Rad18p), DSBR and checkpoint control (as a heterodimer with Bre1p), ubiquitin-mediated N-end rule protein degradation (as a heterodimer with Ubr1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P52492    156   UBC11_YEAST Ubiquitin-conjugating enzyme E2-1...1423e-32     118     42     59GO:0005737; C:cytoplasm; IC:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.
92P35128    151   UBE2N_DROME Ubiquitin-conjugating enzyme E2 N...1418e-32     117     35     67
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0007625; P:grooming behavior; IMP:FlyBase.::GO:0007630; P:jump response; IMP:FlyBase.::GO:0008594; P:photoreceptor cell morphogenesis; IMP:FlyBase.::GO:0072347; P:response to anesthetic; IMP:FlyBase.
93P34477    164   UBC7_CAEEL Probable ubiquitin-conjugating enz...1649e-32     117     37     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
94Q4R4I1    152   UBE2N_MACFA Ubiquitin-conjugating enzyme E2 N...1361e-31     117     38     65GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
95O00103    176   UBC11_SCHPO Ubiquitin-conjugating enzyme E2-2...1421e-31     117     42     61GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IGI:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IMP:PomBase.
96Q9W6H5    158   UBC9A_DANRE SUMO-conjugating enzyme UBC9-A OS...1542e-31     116     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IMP:ZFIN.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:ZFIN.::GO:0007088; P:regulation of mitosis; IMP:ZFIN.
97P56616    179   UBE2C_XENLA Ubiquitin-conjugating enzyme E2 C...1442e-31     117     42     59GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
98Q42541    166   UBC13_ARATH Ubiquitin-conjugating enzyme E2 1...1323e-31     116     42     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
99Q9EQX9    152   UBE2N_RAT Ubiquitin-conjugating enzyme E2 N O...1363e-31     115     38     65GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD.
100Q5R7J6    152   UBE2N_PONAB Ubiquitin-conjugating enzyme E2 N...1364e-31     115     38     65GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
101P61089    152   UBE2N_MOUSE Ubiquitin-conjugating enzyme E2 N...1364e-31     115     38     65GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0031372; C:UBC13-MMS2 complex; ISS:HGNC.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0000729; P:DNA double-strand break processing; ISS:HGNC.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:HGNC.::GO:0016574; P:histone ubiquitination; ISS:HGNC.::GO:0045739; P:positive regulation of DNA repair; ISS:HGNC.::GO:0031058; P:positive regulation of histone modification; ISS:HGNC.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:HGNC.::GO:0006301; P:postreplication repair; ISS:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0033182; P:regulation of histone ubiquitination; ISS:HGNC.::GO:0050852; P:T cell receptor signaling pathway; ISS:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
102P61088    152   UBE2N_HUMAN Ubiquitin-conjugating enzyme E2 N...1364e-31     115     38     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0031372; C:UBC13-MMS2 complex; IDA:HGNC.::GO:0035370; C:UBC13-UEV1A complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; IDA:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0000729; P:DNA double-strand break processing; IMP:HGNC.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:HGNC.::GO:0016574; P:histone ubiquitination; IMP:HGNC.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0045739; P:positive regulation of DNA repair; IMP:HGNC.::GO:0031058; P:positive regulation of histone modification; IMP:HGNC.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:HGNC.::GO:0006301; P:postreplication repair; IMP:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0033182; P:regulation of histone ubiquitination; IMP:HGNC.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
103Q0P5K3    152   UBE2N_BOVIN Ubiquitin-conjugating enzyme E2 N...1364e-31     115     38     65GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
104Q28CQ4    158   UBC9_XENTR SUMO-conjugating enzyme UBC9 OS=Xe...1547e-31     115     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
105P63282    158   UBC9_XENLA SUMO-conjugating enzyme UBC9 OS=Xe...1547e-31     115     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
106Q2EF73    158   UBC9_SPETR SUMO-conjugating enzyme UBC9 OS=(I...1547e-31     115     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
107P63281    158   UBC9_RAT SUMO-conjugating enzyme UBC9 OS=Ratt...1547e-31     115     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:RGD.::GO:0001650; C:fibrillar center; IDA:RGD.::GO:0045202; C:synapse; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0019789; F:SUMO ligase activity; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033145; P:positive regulation of intracellular steroid hormone receptor signaling pathway; IDA:RGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:RGD.::GO:0016925; P:protein sumoylation; IDA:RGD.::GO:0010469; P:regulation of receptor activity; IDA:RGD.
108P63280    158   UBC9_MOUSE SUMO-conjugating enzyme UBC9 OS=Mu...1547e-31     115     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043398; F:HLH domain binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
109P63279    158   UBC9_HUMAN SUMO-conjugating enzyme UBC9 OS=Ho...1547e-31     115     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:BHF-UCL.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0016925; P:protein sumoylation; IDA:BHF-UCL.
110P63283    158   UBC9_CHICK SUMO-conjugating enzyme UBC9 OS=Ga...1547e-31     115     40     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
111Q9DDJ0    157   UBC9B_DANRE SUMO-conjugating enzyme UBC9-B OS...1547e-31     115     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
112Q86K32    154   UBE2N_DICDI Probable ubiquitin-conjugating en...1379e-31     114     36     64
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
113Q42551    160   SCE1_ARATH SUMO-conjugating enzyme SCE1 OS=Ar...1451e-30     114     43     53GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:TAIR.
GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0016925; P:protein sumoylation; IDA:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.
114P25868    168   UBC7_WHEAT Ubiquitin-conjugating enzyme E2 7 ...1322e-30     114     42     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
115Q6Y1Z4    158   UBC9_PAGMA SUMO-conjugating enzyme UBC9 OS=Pa...1545e-30     113     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
116B3NWW9    209   UBE2S_DROER Ubiquitin-conjugating enzyme E2 S...1605e-30     114     36     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
117O13685    148   UBC13_SCHPO Ubiquitin-conjugating enzyme E2 1...1418e-30     112     35     61GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
118Q8LGF7    157   PEX4_ARATH Protein PEROXIN-4 OS=Arabidopsis t...1318e-30     112     40     62GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR.
119P52483    207   UB2E3_MOUSE Ubiquitin-conjugating enzyme E2 E...1371e-29     113     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
120Q969T4    207   UB2E3_HUMAN Ubiquitin-conjugating enzyme E2 E...1371e-29     113     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
121Q2T9X7    207   UB2E3_BOVIN Ubiquitin-conjugating enzyme E2 E...1371e-29     113     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
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