Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGL048C
Length:
405
Number of sequences:
5887
Description:
YGL048C RPT6 SGDID:S000003016, Chr VII from 411286-410069, Genome Release 64-1-1, reverse complement, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P48601    439   PRS4_DROME 26S protease regulatory subunit 4 ...3561e-113     346     49     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0004175; F:endopeptidase activity; IDA:FlyBase.
GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.
32Q0W257    417   PAN_UNCMA Proteasome-activating nucleotidase ...4003e-113     344     45     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
33P62193    440   PRS4_RAT 26S protease regulatory subunit 4 OS...3243e-113     345     51     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:RGD.
GO:0030163; P:protein catabolic process; IEA:InterPro.
34P62192    440   PRS4_MOUSE 26S protease regulatory subunit 4 ...3243e-113     345     51     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
35P62191    440   PRS4_HUMAN 26S protease regulatory subunit 4 ...3243e-113     345     51     70GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; NAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
36Q5R8D7    433   PRS7_PONAB 26S protease regulatory subunit 7 ...3354e-113     345     51     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
37P46471    433   PRS7_MOUSE 26S protease regulatory subunit 7 ...3359e-113     343     51     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
38Q4R4R0    433   PRS7_MACFA 26S protease regulatory subunit 7 ...3351e-112     343     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
39P35998    433   PRS7_HUMAN 26S protease regulatory subunit 7 ...3351e-112     343     51     68GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
40Q5E9F9    433   PRS7_BOVIN 26S protease regulatory subunit 7 ...3351e-112     343     51     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
41Q6LWR0    407   PAN_METMP Proteasome-activating nucleotidase ...3861e-112     342     45     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
42P46472    433   PRS7_XENLA 26S protease regulatory subunit 7 ...3351e-112     343     51     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
43O16368    443   PRS4_CAEEL Probable 26S protease regulatory s...3262e-112     343     50     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
44A9A916    407   PAN_METM6 Proteasome-activating nucleotidase ...3863e-112     342     45     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
45A6VHR1    407   PAN_METM7 Proteasome-activating nucleotidase ...3864e-112     341     45     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
46B8GGN4    412   PAN_METPE Proteasome-activating nucleotidase ...3697e-112     341     44     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
47Q2FQ56    412   PAN_METHJ Proteasome-activating nucleotidase ...3667e-112     340     48     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
48A4G0S4    407   PAN_METM5 Proteasome-activating nucleotidase ...3869e-112     340     45     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
49Q63347    433   PRS7_RAT 26S protease regulatory subunit 7 OS...3352e-111     340     51     68GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
50Q55BV5    439   PRS4_DICDI 26S protease regulatory subunit 4 ...3197e-111     339     50     71GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
51Q90732    440   PRS4_CHICK 26S protease regulatory subunit 4 ...3241e-110     338     50     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
52A7I8B8    436   PAN_METB6 Proteasome-activating nucleotidase ...3672e-110     338     46     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
53Q9SSB4    464   PRS7B_ARATH 26S protease regulatory subunit 7...3904e-110     338     46     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
54P40327    437   PRS4_YEAST 26S protease regulatory subunit 4 ...3266e-110     337     50     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043171; P:peptide catabolic process; IMP:SGD.::GO:0045732; P:positive regulation of protein catabolic process; IDA:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
55Q9SZD4    443   PRS4A_ARATH 26S proteasome regulatory subunit...3247e-110     337     50     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:TAIR.::GO:0005634; C:nucleus; TAS:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009965; P:leaf morphogenesis; IMP:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0035266; P:meristem growth; IMP:TAIR.::GO:0009933; P:meristem structural organization; IMP:TAIR.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:TAIR.::GO:0043248; P:proteasome assembly; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0051788; P:response to misfolded protein; IMP:TAIR.::GO:0048829; P:root cap development; IMP:TAIR.::GO:0090351; P:seedling development; IMP:TAIR.
56P46466    448   PRS4_ORYSJ 26S protease regulatory subunit 4 ...3248e-110     337     50     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
57Q9SL67    443   PRS4B_ARATH 26S proteasome regulatory subunit...3241e-109     336     50     71GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000502; C:proteasome complex; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007292; P:female gamete generation; IGI:TAIR.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0048232; P:male gamete generation; IGI:TAIR.::GO:0030163; P:protein catabolic process; IEA:InterPro.
58A6UQT3    407   PAN_METVS Proteasome-activating nucleotidase ...3721e-109     335     46     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
59O17071    406   PRS10_CAEEL Probable 26S protease regulatory ...3561e-108     332     48     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.
60Q86JA1    428   PRS7_DICDI 26S protease regulatory subunit 7 ...3823e-108     332     46     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0000502; C:proteasome complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
61A3CV35    412   PAN_METMJ Proteasome-activating nucleotidase ...3674e-108     331     45     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
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